Retrorsine-Induced Hepatotoxicity is Mediated by Inhibition of the EGFR/AKT/c-Jun Axis and Disruption of Calcium Homeostasis in Primary Hepatocytes [0.03%]
逆转录病毒诱导的肝毒性通过抑制EGFR/AKT/c-Jun轴和破坏钙稳态在原代肝细胞中介导
Congcheng Zhang,Qin Zhang,Pan Wang et al.
Congcheng Zhang et al.
Pyrrolizidine alkaloids (PAs) occur in approximately 3%-5% of flowering plants and are common natural toxins; retrorsine is among the most hepatotoxic. Ingestion of PA-containing products is a major cause of hepatic sinusoidal obstruction s...
Detriment of mycotoxin contamination in feed and nutrition-based prevention and control strategies: A review [0.03%]
饲料和营养-based防控策略在防治霉菌毒素污染中的作用及局限性——综述文章
Shijie Fan,Kunru Teng,Jiefeng Li et al.
Shijie Fan et al.
The health of humans and livestock is significantly compromised by the pervasive and serious issue of mycotoxin contamination in crops. Exploring ways to eliminate mycotoxin contamination is a global concern. In vivo biological prevention a...
Transcriptome based functional atlas of venomous spines: A first report on Dwarf lionfish [0.03%]
基于转录组的毒刺功能图谱：矮狮子鱼首次报告
Parthkumar Prajapati,Ketankumar Panchal,Prakash Koringa et al.
Parthkumar Prajapati et al.
Fish venoms constitute highly specialized biochemical systems, yet their molecular composition and gene-expression architecture remain poorly resolved in many venomous teleosts. In lionfishes, venom is delivered through fin-associated spine...
INFLUENCE OF THE ABO SYSTEM ON THE HEMOLYTIC ACTIVITY OF MEDICALLY RELEVANT LOXOSCELES VENOMS IN BRAZIL [0.03%]
巴西洛沃斯奇蜘蛛毒液的溶血活性与ABO系统的影响关系研究
Martina Beltramino,Isabella Gizzi Jiacomini,Bianca Prado-Costa et al.
Martina Beltramino et al.
Envenomation by Loxosceles spiders is an important public health issue, frequently associated with hemolysis. Although the ABO blood group system influences various diseases, its role in loxoscelism is poorly understood. This study evaluate...
AFM1 binding by Lactobacillus acidophilus, Lactobacillus rhamnosus and Enterococcus faecalis in human breast milk under different incubation conditions [0.03%]
三种益生菌在不同条件下结合人乳中的黄曲霉毒素M1
Gülcan Çelik,Aydın Vural,Berna Duman Aydın
Gülcan Çelik
This study investigated the ability of selected probiotic strains to bind aflatoxin M1 (AFM1), a hydroxylated metabolite of aflatoxin B1 classified as a Group 2B carcinogen by the International Agency for Research on Cancer (IARC). Human br...
Assessment of acute dermal toxicity of Croton pulegiodorus Baill. leaf essential oil in mice [0.03%]
评估巴油香蕾芹属植物叶片精油对小鼠的急性皮肤毒性大小
Patryck Érmerson Monteiro Dos Santos,Matheus Cavalcanti de Barros,Thaís Paes de Freitas et al.
Patryck Érmerson Monteiro Dos Santos et al.
Croton pulegiodorus Baill. leaf essential oil (CPLEO) has demonstrated insecticidal activity and is a promising candidate for the development of formulations aimed at controlling insect pests, as well as for use as a repellent. This study i...
Primary photosensitization in horses associated with ingestion of Malachra fasciata Jacq. (Malvaceae) in the Northeast of Brazil [0.03%]
巴西东北部马利克ra fasciata Jacq. (锦葵科) 饲喂与马来鞍背斑叶敏感反应的关系
Lourdes Fernández Riquelme,Valber Onofre de Araújo,Thatyana Kelly Ferreira da Silva et al.
Lourdes Fernández Riquelme et al.
Malachra fasciata Jacq. (Malvaceae) is an invasive plant widely found in Northeastern Brazil and has been experimentally demonstrated to cause severe dermatitis in sheep. However, its toxic effects in horses have not previously been documen...
Study on the venom of Bothrops ammodytoides from La Pampa (Argentina) and some toxicological, biochemical and immunological characteristics [0.03%]
阿根廷拉潘帕地区的Bothropsammodytoides蛇毒的研究及一些毒理学、生化和免疫学特性分析
M Bruni,L Lanari,J Van Grootheest et al.
M Bruni et al.
Bothrops (B.) ammodytoides is the southernmost viper species in the world and is endemic to Argentina, where it is distributed from the northwest to southern Patagonia. In La Pampa, northern Patagonia where it inhabits, snakebite incidents ...
Safety assessment of Scabiosa ucranica L.: Elemental analysis and acute oral toxicity in rats [0.03%]
Scabiosa ucrainica L.的安全评估：元素分析和急性经口毒性研究
Pshtiwan A Masum,Fuad O Abdullah
Pshtiwan A Masum
Scabiosa ucranica L. is lacking in thorough phytochemical and toxicological assessment. The scientific evaluation of medicinal plants is essential for safety. This research studied the safety profile of S. ucranica using elemental compositi...
Bothrops mattogrossensis Snake Venom: how age and sex shape the chemistry of the envenoming [0.03%]
伯霍普斯毒蛇 venom：年龄和性别对中毒化学成分的影响
Gisele Akemi Tsuboi-Sato,Lídia Jorge Tasima,Eduardo Oliveira Venancio de Lima et al.
Gisele Akemi Tsuboi-Sato et al.
In Brazil, the genus Bothrops is the main responsible for snakebite envenomation. Compositional variations in venoms can occur intra and interspecifically, influenced by age, sex, geographic distribution, seasonality and diet. This study bi...