Under pressure: mapping the distribution of medically important Tityus Koch, 1836 (Buthidae) scorpions in Brazil using a century of Instituto Butantan records [0.03%]
受压之下：利用一个世纪的布坦扬研究所记录绘制巴西药用重要科赫蜈蚣(Tityus)(Buthidae)的分布图
Paulo A M Goldoni,Antonio D Brescovit,Rodrigo A Castro-Souza et al.
Paulo A M Goldoni et al.
The buthid scorpions Tityus serrulatus, T. bahiensis, T. obscurus, and T. stigmurus are considered the most medically significant species in Brazil. Since the early 1900s, their identification and distribution have been central to the zoolo...
In vitro inhibition of snake venom toxins by varespladib, marimastat, nafamostat and dimercaprol [0.03%]
用生物化学方法研究几种化合物对毒蛇毒素的体外抑制作用
Anandie le Roux,Stephanus J Cloete,Jacobus P Petzer et al.
Anandie le Roux et al.
Snakebite envenoming causes more than 130,000 deaths and more than 400,000 disabilities per year and has been classified as a priority Neglected Tropical Disease by the World Health Organization (WHO). While antivenom therapy remains the ma...
Occurrence of nodularin in South African waters by high-performance liquid chromatography [0.03%]
高效液相色谱法检测南非水域中的微囊藻毒素LR
Zama Mthembu,Hogantharanni Govender,Bhekumuzi Gumbi
Zama Mthembu
Nodularins are hepatotoxic cyclic pentapeptides produced by the cyanobacterium Nodularia spumigena, which is frequently associated with harmful algal blooms in brackish and freshwater environments. These cyanotoxins pose serious environment...
Comparative analysis of the applicability of prediction software to microcystin toxicity evaluation [0.03%]
预测软件微囊藻毒素毒性的适用性分析比较
Cristiane Gonçalves da Silva,Cristina Viana Niero,Marcelo Dutra Duque et al.
Cristiane Gonçalves da Silva et al.
Application of software for toxicity analysis of cyanobacterial toxin remains poorly explored compared to such approach in other areas. Predictive software has been extensively used in the discovery of new drugs and assessment of cosmetics ...
First description of envenomation by a probable Atractaspis dahomeyensis Bocage, 1887 in Togo (Serpentes, Atractaspididae) [0.03%]
记述多哥一种拟夜蛇属(Atractaspis)蛇的致伤病例（爬行纲，夜蛇科）
Christian Marty,Idab Akakpo,Nwelab Koffi et al.
Christian Marty et al.
We report the first case of a probable Atractaspis dahomeyensis envenomation in Togo, West Africa. To our knowledge, this is the first description of an Atractaspis envenomation in this country. The clinical and biological aspects of the en...
Emerging Mycotoxic Syndromes in France: Epidemiological Trends and Public Health Implications (2015-2022) [0.03%]
法国的新型霉毒综合征：2015-2022年的流行病学趋势与公共卫生影响
Chloé Bruneau,Manon Poilane,Jérémy Lecot;French PCC research group;Anne Landreau et al.
Chloé Bruneau et al.
Mushroom poisoning is a common cause of toxic exposure, and several "new mycotoxic syndromes" have been recognized since the 1990s. We conducted a retrospective multicenter study using the French Poison Control Centers cases database to des...
Fatal Bothrops atrox snakebite with thrombotic microangiopathy, hemorrhagic stroke and acute kidney injury [0.03%]
致死型Bothrops atrox蛇咬伤合并血栓性微血管病、出血性中风和急性肾损伤
Larissa Rocha Alípio Duarte,Érica Carvalho,Tigran Francis Chehuan Melo et al.
Larissa Rocha Alípio Duarte et al.
Bothrops atrox is responsible for most snakebite envenomations in the Amazon region. Its venom induces systemic hemostatic disturbances and local tissue damage, potentially leading to severe complications. This report describes a fatal case...
Four-Year Surveillance of Mycotoxins in Feed and Raw Materials (2021-2024): Occurrence, Co-Contamination, and Risk Implications [0.03%]
2021-2024年饲料及原料中霉菌毒素四年监测：污染状况、共存特征及风险评估
Paweł Skrzydlewski,Robert Kosicki,Jan Grajewski et al.
Paweł Skrzydlewski et al.
Mycotoxins are secondary metabolites produced by molds, primarily by species of Penicillium, Fusarium, and Aspergillus genera. They are widespread contaminants of foods, feeds and various feed materials. This study aimed to evaluate the lev...
Antinociceptive and neuromodulatory effects of the scorpion venom tetrapeptide tetrascorpin-1 in a long-lasting pain hypersensitivity model in mice [0.03%]
四肽tetrascorpin-1的镇痛和神经调节作用及其在小鼠长时间疼痛过敏模型中的效果研究
Salvatore Pagano,Rebecca Limongelli,Wassim Moslah et al.
Salvatore Pagano et al.
We evaluated the effects of Tetrascorpin-1 from Androctonus australis (AaTs-1), a tetrapeptide obtained from scorpion venom, previously hypothesized to bind the formyl peptide receptor like-1 (FPRL-1) known as formyl peptide receptor-2 (FPR...
Venom gland transcriptomics of the Black Judaicus scorpion (Hottentotta judaicus) reveals its toxin arsenal and potential bioeconomic value [0.03%]
黑犹地卡斯corpopsis venom腺转录组揭示其毒素库及潜在生物经济价值
Tim Lüddecke,Josephine Dresler,Sabine Hurka et al.
Tim Lüddecke et al.
Scorpion venoms are likewise a medical burden as well as a source of novel bioresources. Despite their important dual role, the venoms of most scorpion species remain under- or unstudied. Among these is the venom of the Black Judaicus scorp...