Integrated testing strategies can be optimal for chemical risk classification [0.03%]
集成测试策略可适用于化学品风险分类
Marko Raseta,Jon Pitchford,James Cussens et al.
Marko Raseta et al.
There is an urgent need to refine strategies for testing the safety of chemical compounds. This need arises both from the financial and ethical costs of animal tests, but also from the opportunities presented by new in-vitro and in-silico a...
Control aspects of the human cardiovascular-respiratory system under a nonconstant workload [0.03%]
非恒定负荷下人体心血管呼吸系统的控制方面
Pio Gabrielle B Calderon,Mustafa Habib,Franz Kappel et al.
Pio Gabrielle B Calderon et al.
The human cardiovascular system (CVS) and respiratory system (RS) work together in order to supply oxygen (O2) and other substrates needed for metabolism and to remove carbon dioxide (CO2). Global and local control mechanisms act on the CVS...
Dynamics analysis of a delayed reaction-diffusion predator-prey system with non-continuous threshold harvesting [0.03%]
具有非连续阈值收获的时滞反应扩散系统的动力学分析
Xuebing Zhang,Hongyong Zhao
Xuebing Zhang
This paper deals with a delayed reaction-diffusion predator-prey model with non-continuous threshold harvesting. Sufficient conditions for the local stability of the regular equilibrium, the existence of Hopf bifurcation and Turing bifurcat...
Pattern formation in a nonlocal mathematical model for the multiple roles of the TGF-β pathway in tumour dynamics [0.03%]
非局部数学模型中TGF-β通路在肿瘤动力学中的多重作用的图案形成
Raluca Eftimie,Matthieu Perez,Pietro-Luciano Buono
Raluca Eftimie
The growth and invasion of cancer cells are very complex processes, which can be regulated by the cross-talk between various signalling pathways, or by single signalling pathways that can control multiple aspects of cell behaviour. TGF-β i...
Selection of discriminant mid-infrared wavenumbers by combining a naïve Bayesian classifier and a genetic algorithm: Application to the evaluation of lignocellulosic biomass biodegradation [0.03%]
基于贝叶斯分类器和遗传算法组合选择判别中红外波数及其在评价木质纤维素生物质生物降解中的应用
Abbas Rammal,Eric Perrin,Valeriu Vrabie et al.
Abbas Rammal et al.
Infrared spectroscopy provides useful information on the molecular compositions of biological systems related to molecular vibrations, overtones, and combinations of fundamental vibrations. Mid-infrared (MIR) spectroscopy is sensitive to or...
A stochastic vector-borne epidemic model: Quasi-stationarity and extinction [0.03%]
随机媒介流行病学模型及其灭绝和亚稳态行为
Tom Britton,Ali Traoré
Tom Britton
We consider a stochastic model describing the spread of a vector borne disease in a community where individuals (hosts and vectors) die and new individuals (hosts and vectors) are born. The time to extinction of the disease, TQ, starting in...
Asymptotic tracking and disturbance rejection of the blood glucose regulation system [0.03%]
血糖调节系统的渐近跟踪与扰动抑制
Brandon Ashley,Weijiu Liu
Brandon Ashley
Type 1 diabetes patients need external insulin to maintain blood glucose within a narrow range from 65 to 108 mg/dl (3.6 to 6.0 mmol/l). A mathematical model for the blood glucose regulation is required for integrating a glucose monitoring ...
Ying Chen,Brendan C Fry,Anita T Layton
Ying Chen
The metabolism of glucose provides most of the ATP required for energy-dependent transport processes. In the inner medulla of the mammalian kidney, limited blood flow and O2 supply yield low oxygen tension; therefore, a substantial fraction...
Quantifying the role of immunotherapeutic drug T11 target structure in progression of malignant gliomas: Mathematical modeling and dynamical perspective [0.03%]
免疫治疗药物T11靶向结构在恶性胶质瘤进程中的作用量化：数学建模与动力学视角
Subhas Khajanchi,Sandip Banerjee
Subhas Khajanchi
The paper describes a mathematical model with synergistic interaction between the malignant glioma cells and the immune system, namely, macrophages, activated Cytotoxic T-Lymphocytes (CTLs), the immunosuppressive cytokine Transforming Growt...
Calcium dynamics in cardiac excitatory and non-excitatory cells and the role of gap junction [0.03%]
钙在心脏兴奋和非兴奋细胞中的动态变化及缝隙连接的作用
Phonindra Nath Das,Parul Mehrotra,Aseem Mishra et al.
Phonindra Nath Das et al.
Calcium ions aid in the generation of action potential in myocytes and are responsible for the excitation-contraction coupling of heart. The heart muscle has specialized patches of cells, called excitatory cells (EC) such as the Sino-atrial...