Structure-activity relationship of a potent anti-FXase and antithrombotic chondroitin sulfate-dermatan sulfate hybrid bearing 2,3-O-sulfated motifs from Anthenoides laevigatus [0.03%]
安田海参中抗FXa和抗血栓的透明质衍生物状素的构效关系研究(含有2,3-O-硫酸盐结构)
Xiang Shi,Minghao Shi,Jiewen Fu et al.
Xiang Shi et al.
This study isolated a homogeneous polysaccharide ALHX-2M from the body wall of the starfish Anthenoides laevigatus (South China Sea). Structural characterization identified it as a chondroitin sulfate-dermatan sulfate (CS-DS) hybrid chain w...
Dynamic boronate ester crosslinked hyaluronic acid hydrogel patch enabling fast dissolution and rapid oral mucosal delivery of amorphous sumatriptan [0.03%]
动态交联的透明质酸水凝胶贴片促进无定形舒马曲坦的快速溶解和口腔黏膜递送
Zhuohao Gu,Jiafeng Wang,Xinglei Shi et al.
Zhuohao Gu et al.
Developing mucoadhesive and fast-dissolving drug delivery systems for oral mucosal applications remains a clinical challenge. Here, we report a pH-responsive phenylboronic acid-modified hyaluronic acid (HA-PBA) hydrogel film for efficient t...
Prebiotic low methoxyl pectin-alginate for colon-targeted Companilactobacillus crustorum MN047 delivery in alleviating ulcerative colitis: Synergy and comparative analysis [0.03%]
低甲氧基果胶-海藻酸钠前体药物递送乳酸菌Companilactobacillus crustorum MN047用于治疗溃疡性结肠炎:协同效应与比较分析
Fan Zhang,Hanxiang Wang,Beisenbayeva Kamila et al.
Fan Zhang et al.
Probiotics and prebiotics show promise in alleviating ulcerative colitis (UC). This study compared pectin-based and alginate-based probiotic polysaccharide composite hydrogel beads (PPHB) with or without Companilactobacillus crustorum MN047...
Comparative Study
Carbohydrate polymers. 2026 Mar 1:375:124750. DOI:10.1016/j.carbpol.2025.124750 2026
GH28 polygalacturonase of human gut Bacteroides spp. confers the degradation of a novel branched galacturonan isolated from Jasminum nudiflorum [0.03%]
人类肠道细菌拟杆菌属的GH28半乳糖醛酸聚糖酶可降解梅花探春中的一种新型支链半乳糖醛酸聚糖
Yun Li,Tingmei Hu,Meixia Li et al.
Yun Li et al.
The specific enzymes responsible for metabolizing distinct pectin structures have not been fully elucidated due to the structural diversity of pectin. Thus, we hypothesize that there may be other enzymes to target pectin. Here, a novel pect...
Pulsed electric field-driven electrokinetic removal of starch granule-channel proteins for enhanced starch modification [0.03%]
用于增强淀粉改性的脉冲电场驱动的静电动力学淀粉颗粒通道蛋白去除法
Xindong Xu,Yongxin Teng,Kaiyang Shi et al.
Xindong Xu et al.
Efficient, eco-friendly removal of starch granule-channel proteins (SGCP) to enhance modifier penetration has been challenging. Current methods using chemical/biological reagents (denaturants, alkalis, proteases) suffer from toxicity, long ...
Starch-unsaturated fatty acid complexes with antioxidant protection and slow-digesting properties: Effects of complexing time [0.03%]
淀粉不饱和脂肪酸复合物的抗氧化和缓慢消化性能:形成时间的影响分析
Yiming Zhang,Changhui Shao,Jinglin Yu et al.
Yiming Zhang et al.
Starch-unsaturated fatty acid (UFA) complexes have been shown to present additional functionalities compared to starch-saturated FA complexes. However, little information is available regarding the effects of complexing time on the formatio...
Gellan gum electrohydrodynamic microencapsulation of probiotics for intestine-targeted delivery [0.03%]
用于肠道靶向递送益生菌的gellean gum电水动力微胶囊化技术
Lorenzo Zavagna,Alberto Alfano,Marta Bianchi et al.
Lorenzo Zavagna et al.
Microencapsulation is a promising strategy to improve time-stability, viability and targeted delivery of probiotics, thus enhancing their beneficial roles in the intestine. However, areas of improvement persist, including optimal viability ...
Amylose content of sorghum starches measured by four different methods in relation to molecular structures of sorghum amylose and amylopectin [0.03%]
四种不同方法测定的高梁直链淀粉含量与其直链淀粉和支链淀粉分子结构关系的研究
Dongxing Li,Xiaorong Wu,Scott R Bean et al.
Dongxing Li et al.
Amylose content plays an important role in functional and nutritional properties of starches and flours, yet different amylose contents are often reported from different analytical methods for the same sample. The objectives of this study w...
pH-controlled complex coacervation of OSA-modified starch and chitosan with enhanced oxidative stability of flaxseed oil [0.03%]
用于强化亚麻籽油氧化稳定性的OSA改性淀粉和壳聚糖的pH控制复杂共聚集体系研究
Weiming Chen,Yirong Yuan,Bin Zhang et al.
Weiming Chen et al.
Understanding the effect of pH on complex coacervation is essential for designing functional oil delivery systems. This study investigated the physicochemical properties, structural characteristics, and oil-water interfacial behavior of com...
Chitosan and chito-oligosaccharides as multifunctional therapeutics for metabolic dysfunction-associated steatotic liver disease (MASLD) [0.03%]
壳多糖和低聚壳寡糖作为代谢功能紊乱相关性脂肪肝病的多功能治疗剂
Gaoli Zhou,Ronge Xing,Zongji Wang et al.
Gaoli Zhou et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously called metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic fatty liver disease (NAFLD), has emerged as a leading cause of chronic liver ...