Quantified calcification in rat aortic valves isolated with the sinus of Valsalva coordinates with calciprotein particles formation [0.03%]
包含窦管无残基的分离主动脉瓣中钙化定量与钙结合蛋白颗粒形成相协调
Shota Morikane,Koichi Ishida,Naoki Ashizawa et al.
Shota Morikane et al.
Background: Aortic valve sclerosis, in which calcification is a major pathogenesis, is a serious complication of chronic kidney disease. In small animal experiments, it is difficult to evaluate aortic valve calcification ...
Variable regional histomorphology of the ascending aorta: Implications for disease classification [0.03%]
升主动脉区域组织形态学的变异性和疾病分类的意义
Collin S Pryma,Md Shahrier Amin,Charles Leduc et al.
Collin S Pryma et al.
Regional differences in the normal histology of the ascending aorta have not been systematically studied, possibly resulting in diagnostic misinterpretation. This study aims to characterize the normal histologic spectrum of the aortic sinus...
Pathological capillary analysis of ischemia with non-obstructive coronary arteries in a Fabry disease patient receiving enzyme replacement therapy [0.03%]
一名接受酶替代治疗的法布雷病患者的非冠状动脉阻塞性缺血的病理毛细血管分析
Hiromitsu Kanamori,Genki Naruse,Shingo Minatoguchi et al.
Hiromitsu Kanamori et al.
Fabry disease is a lysosomal disorder caused by an a-galactosidase A deficiency, which often causes angina in the absence of epicardial coronary artery stenosis. It is conceivable that epicardial and microvascular coronary dysfunction due t...
Thoracic aortic diseases: Identification of diagnostic biomarkers using proteomic analysis [0.03%]
胸部主动脉疾病：利用蛋白质组分析鉴定诊断生物标志物
Nico Arndt,Thomas Mair,Maria Riedner et al.
Nico Arndt et al.
Introduction: Thoracic aortic aneurysms frequently go undetected until serious complications like acute dissections or ruptures arise. Therefore, this study aims to identify potential blood circulating biomarkers enabling...
The orphan receptor GPRC5B promotes macrophage infiltration and an inflammatory plaque phenotype in atherosclerosis [0.03%]
孤儿受体GPRC5B通过促进巨噬细胞浸润在动脉粥样硬化中发挥促炎作用
Greta Verena Freundt,Friedrich Alexander von Samson-Himmelstjerna,Jan-Thorge Nitz et al.
Greta Verena Freundt et al.
Background and aims: Atherosclerosis is driven by chronic inflammation of the vascular wall, in which macrophages play a central role. The orphan G protein-coupled receptor GPRC5B is expressed in vascular cells and macrop...
Clinical Significance of C4d Positivity Within the First Month after Heart Transplantation in Detecting Antibody-Mediated Rejection on Endomyocardial Biopsies [0.03%]
心脏移植术后1个月内C4d阳性对心内膜活检标本抗体介导排斥的诊断价值及临床意义
Mengxue Zhang,Yan Zhou,Chrystalle Katte Carreon et al.
Mengxue Zhang et al.
Background: The pathologic definition for antibody-mediated rejection (AMR) includes both histopathological and immunopathological components. C4d is the most validated diagnostic marker for immunopathologic AMR; however,...
Giovanni Maria Lancisi (1654-1720) and the First Historical Investigation on Pathology of Sudden Death [0.03%]
Giovanni Maria Lancisi（1654-1720）与猝死病理学的首次历史调查
Daniela Marrone,Cristina Basso,Gaetano Thiene
Daniela Marrone
Between 1705 and 1706, Rome experienced a series of sudden deaths, prompting Pope Clement XI to set up a commission to investigate the causes. Giovanni Maria Lancisi, a prominent physician, oversaw forensic autopsies and wrote "De subitanei...
Aortic valve morphology rather than aortic valve function, aortic dilatation, and age interferes with ascending aortic structural and biomechanical properties [0.03%]
主动脉瓣形态而非主动脉瓣功能、主动脉扩张和年龄影响升主动脉的结构和生物力学性质
Jan M Federspiel,Jan-Christian Reil,Peter H Schmidt et al.
Jan M Federspiel et al.
Aortic valve (AV) malformation and AV malfunction have been linked to aortic wall degeneration. Studies concomitantly assessing AV morphology, AV function, age, ascending aortic dilatation, and aortic biomechanical properties are lacking. T...
"Aortic Regurgitation as a Cause of Sudden Cardiac Death with Aortic and Left Ventricular Remodelling - The Role of the Bicuspid Valve." [0.03%]
"主动脉反流作为突发性心脏死亡的原因并伴有主动脉和左心室重塑-双叶瓣的作用。"
Lauren Moran,Joseph Westaby,Mary N Sheppard
Lauren Moran
Background and objective: Aortic regurgitation (AR) results in blood flow from the aorta back into the left ventricle, which leads to left ventricular hypertrophy and dilation which, in a clinical setting, leads to heart ...
Prevalence of amyloid deposition in patients undergoing surgical myectomy for presumed hypertrophic cardiomyopathy [0.03%]
疑似肥厚型心肌病外科手术患者的心脏淀粉样变患病率
David S Katzianer,Deborah H Kwon,Maran Thamilarasan et al.
David S Katzianer et al.
Background: Cardiac amyloidosis (CA) and hypertrophic cardiomyopathy (HCM) share the phenotypic characteristic of increased left ventricular wall thickness and, while more common with HCM, both conditions can result in dy...