Iron deficiency drives pathological cardiac remodeling and diastolic dysfunction associated with inhibition of AMPK-mTORC1 signaling [0.03%]
铁缺乏通过抑制AMPK-mTORC1信号通路驱动心脏重构和舒张功能障碍
Dehui Li,Haichu Wen,Bokang Qiao et al.
Dehui Li et al.
Background: Epidemiological evidence has established a strong association between iron deficiency (ID) and the exacerbation of heart failure (HF) and increased mortality. However, the molecular mechanisms by which iron de...
Pavitra Attanayake,Stephen Cohle,Ping Zhang
Pavitra Attanayake
Atrial fibrillation and sudden cardiac death, a nested case-control study looking at cardiac pathology [0.03%]
心房颤动和突发性心脏死亡的病例对照研究——对心脏病理学的研究
Isaac Chung,Mary Sheppard,Joseph Westaby
Isaac Chung
Atrial fibrillation (AF) is the most common heart rhythm disorder with an estimated prevalence of 2-4% in adults. AF is a recognised risk factor for sudden cardiac death (SCD) and has been associated with most cardiac diseases. As the atria...
At the intersection of endomyocardial biopsy and dd-cfDNA, where do we go? [0.03%]
心内膜活检与细胞-free循环DNA交叉领域:我们该何去何从?
Gregory A Fishbein,Marc K Halushka
Gregory A Fishbein
Cardiac allograft rejection has traditionally been assessed by endomyocardial biopsy (EMB). Blood-based assays such as donor-derived cell-free DNA (dd-cfDNA) are increasingly used, yet emerging data highlight discordance between these appro...
Letter to the editor [0.03%]
致编辑的信
Bjarke Jensen,Ionela-Simona Visoiu
Bjarke Jensen
Pericardial and interstitial alcianophilic gelatinous degeneration in anorexia nervosa [0.03%]
神经性厌食的心包和间质类黏液样胶原变性
Eleonora Nardi,Chiara Siodambro,Letizia Del Bello et al.
Eleonora Nardi et al.
Anorexia nervosa is associated with severe cardiovascular complications and an increased risk of sudden death. While cardiac atrophy is well recognized, unusual connective-tissue alterations of the heart are rarely described. A 28-year-old ...
Trichrome, Congo red, and Thioflavin S Stains are Comparable for the Diagnosis of Amyloid Deposits in Endomyocardial Biopsies [0.03%]
三色、刚果红和硫黄素S染色诊断心肌活检组织中淀粉样沉积物的价值相近
Justin Burk,Alexander N Wein,Michael M Binkley et al.
Justin Burk et al.
Introduction: Despite imaging advancements, proper management for cardiac amyloidosis hinges on accurate diagnosis and subtyping of amyloid in endomyocardial biopsies (EMBx). Nonetheless, the approach toward identifying a...
Usefulness of electron microscopy in the diagnosis of heterozygous Fabry disease with left ventricular outflow tract obstruction masquerading as hypertrophic cardiomyopathy [0.03%]
电镜在左室流出道梗阻型异染性脑白质营养不良(假性肥厚型心肌病)诊断中的应用价值评估
Hiromitsu Kanamori,Tamami Yoshida,Matsumoto Hideki et al.
Hiromitsu Kanamori et al.
Fabry disease, characterized by α-galactosidase A (GLA) deficiency, causes left ventricular hypertrophy (LVH) often mimicking hypertrophic cardiomyopathy (HCM). Differentiating Fabry disease from HCM is crucial, given their therapeutic and...
Corrigendum to "The mitochondrial uncoupler 2,4-dinitrophenol modulates inflammatory and oxidative responses in Trypanosoma cruzi -induced acute myocarditis in mice" [Cardiovascular Pathology 72 (2024) 107653] [0.03%]
关于“线粒体解偶联剂2,4-二硝基苯酚调节克鲁氏锥虫诱导的小鼠急性心肌炎的炎症和氧化反应”一文的勘误[心血管病理学72(2024)107653]
José Edson Caetano-da-Silva,Elda Gonçalves-Santos,Elisa L B C Domingues et al.
José Edson Caetano-da-Silva et al.
Genetic Mutations, Pathology, and Single-nucleus Transcriptomic Landscape in LVHT Patients Reveal Differential Progression to Heart Transplantation [0.03%]
遗传变异、病理和单细胞转录组景观揭示了LVHT患者向心脏移植发展的不同进程
Yifan Wang,Weiteng Wang,Han Mo et al.
Yifan Wang et al.
Background: Left ventricular hypertrabeculation/non-compaction (LVHT/LVNC) is characterized by a thinned myocardial wall, prominent trabeculations, and deep intertrabecular recesses. It presents with unique cardiac morpho...