Region-wise stacking ensembles for estimating brain-age using structural MRI [0.03%]
基于结构磁共振图像的脑年龄估计的区域堆叠集成方法
Georgios Antonopoulos,Shammi More,Simon B Eickhoff et al.
Georgios Antonopoulos et al.
Predictive modeling using structural magnetic resonance imaging (MRI) data is a prominent approach to study brain-aging. Machine learning frameworks have been employed to improve predictions and explore healthy and accelerated aging due to ...
Nuclear segmentation in four-dimensional label-free microscopy images for predicting live birth potential of mouse embryos [0.03%]
基于四维无标记显微图像的核分割以预测小鼠胚胎的活产潜能
Taichi Kanazawa,Tatsuma Yao,Sora Takeshita et al.
Taichi Kanazawa et al.
Assisted reproductive technology (ART), including in vitro fertilization, is one of the most common treatments for infertility. Assessment of embryo quality is an important step in selecting embryos with high birth potential in ART. However...
Optimized design of lower limb exoskeleton based on human biomechanical analysis [0.03%]
基于人体生物力学分析的下肢外骨骼优化设计
Lizhen Zhang,Mengxiang Zhu,Bo Jiang
Lizhen Zhang
To address the current issue in exoskeleton research and development, where studies on the impact of exoskeletons on human muscles and bones are often overlooked prior to prototype manufacturing, leading to prolonged design cycles and high ...
Evaluating generalization of arm movement identification using machine learning: From structured to semi-structured environments [0.03%]
基于机器学习的臂运动识别在结构化和半结构化环境中的泛化评估
Sahel Akbari,Herwin L D Horemans,Johannes B J Bussmann et al.
Sahel Akbari et al.
Home-based rehabilitation is essential for stroke survivors, facilitating motor recovery and improving activities-of-daily-life performance. Recent advances in wearable technologies and machine learning promise to revolutionize home-based a...
Repurposing piroxicam as an SLC7A5 antagonist to ameliorate prothrombotic state in Diane-35-treated polycystic ovary syndrome patients [0.03%]
重新定位吡罗昔康作为SLC7A5拮抗剂以改善Diane-35治疗的多囊卵巢综合征患者的促血栓形成状态
Shan Jiang,Yutong Li,Xiufeng Lin et al.
Shan Jiang et al.
This multidisciplinary investigation employed an integrated clinical-translational framework to comprehensively evaluate the efficacy and treatment-emergent thrombotic risk of Diane-35 in polycystic ovary syndrome (PCOS). In a prospective s...
Enhanced LLM-supported instructions for medication use through retrieval-augmented generation [0.03%]
通过检索增强生成改进的LLM支持的药物使用指令
Davi Dos Reis de Jesus,Antônio Pereira de Souza Júnior,Elisa Tuler de Albergaria et al.
Davi Dos Reis de Jesus et al.
Prescription systems support medication treatment by standardizing content, enhancing legibility and promoting correct dispensation. Challenges remain to personalize use instructions with sufficient clarity to meet patients' needs. Large La...
Disruption of histidine biosynthesis in Acinetobacter baumannii by Tubuloside B from Cistanche tubulosa [0.03%]
肉苁蓉中的筒叶花斛素通过破坏鲍曼不动杆菌组氨酸合成途径而发挥抗菌活性
Anamika Singh,Surabhi Pandit,Tej P Singh et al.
Anamika Singh et al.
The alarming rise of multidrug-resistant Acinetobacter baumannii, a WHO priority pathogen causing hospital-acquired infections, demands innovative antibacterial strategies beyond traditional antibiotics. With stalled antibiotic development ...
CBVLM: Training-free explainable concept-based Large Vision Language Models for medical image classification [0.03%]
CBVLM：训练免费的基于概念的大型视觉语言模型在医学图像分类中的解释性研究
Cristiano Patrício,Isabel Rio-Torto,Jaime S Cardoso et al.
Cristiano Patrício et al.
The main challenges limiting the adoption of deep learning-based solutions in medical workflows are the availability of annotated data and the lack of interpretability of such systems. Concept Bottleneck Models (CBMs) tackle the latter by c...
The integrated multiple event representation framework (IMERF): a case study on critically-ill patients [0.03%]
集成多事件表达框架（IMERF）：危重病人的病例研究
Ivan Olier,Sandra Ortega-Martorell,George Margereson et al.
Ivan Olier et al.
This study introduces the Integrated Multiple Event Representation Framework (IMERF), a novel methodological approach for developing risk prediction models for multiple clinical events. Using a two-stage process involving multi-task learnin...
TargetRX Atlas: a database of experimentally supported mRNAs and drug targets in disease [0.03%]
目标药物图集：一种实验支持的疾病mRNA和药物靶标数据库
Yuxiang Liu,Fan Xu,Tao Wang et al.
Yuxiang Liu et al.
The role of mRNAs in the occurrence, development, and treatment of diseases has been extensively studied in recent years. For basic researchers, the vast amount of disease-related data is becoming increasingly complex and difficult to integ...