The structure of the porcine uterine-conceptus interface is associated with gestational day, fetal size and sex [0.03%]
妊娠天数、胎儿大小和性别与猪子宫-概念株接口结构相关性研究
Tailine Rayane Lima Reis,João Vitor Lopes-Ferreira,Karen Beatriz Guerra et al.
Tailine Rayane Lima Reis et al.
This study aimed to characterize histological changes of the maternal-conceptus interface in feto-placental units associated with fetal weight and sex throughout pregnancy. Pregnant Large-White X Landrace gilts(n=18) were euthanized and hys...
Distribution and sequence analysis of the melanocortin 2 receptor in horses and ponies [0.03%]
马和矮马的促黑激素2受体的分布及序列分析
Christina M Cash,Melody A de Laat
Christina M Cash
The melanocortin 2 receptor (MC2R) has relevance to equine pituitary pars intermedia dysfunction (PPID), as it is the primary binding site for ACTH, which circulates at elevated concentrations in animals affected by PPID. Despite this, litt...
Short-term clinical and biochemical responses following treatment with dapagliflozin or ertugliflozin in horses with hyperinsulinemia: A retrospective case series [0.03%]
回顾性病例系列研究马匹高胰岛素血症接受达格列净或特哥列净治疗后的短期临床和生化反应
Tania Sundra,Edd Knowles,David Rendle et al.
Tania Sundra et al.
The metabolic and lipid profiles of horses treated with sodium-glucose cotransporter 2 inhibitors are not well understood. This retrospective study evaluated blood parameters in hyperinsulinemic horses treated with either ertugliflozin (0.0...
F Frers,J Delarocque,K Feige et al.
F Frers et al.
The underlying molecular mechanisms leading to insulin dysregulation are poorly understood in horses. Therefore, this study aimed to determine if insulin dysregulation is associated with an altered basal expression and extent of phosphoryla...
Effect of short-term dopamine reduction on insulin sensitivity and post-prandial insulin and glucose responses in Standardbred horses [0.03%]
短期多巴胺耗尽对标准马匹胰岛素敏感性及餐后血糖和胰岛素反应的影响
Nicolas C Galinelli,Nicholas J Bamford,Madison L Erdody et al.
Nicolas C Galinelli et al.
The role of dopamine in the regulation of insulin secretion in horses is poorly understood and requires further investigation. Pituitary pars intermedia dysfunction (PPID) is associated with decreased activity of dopaminergic neurons which ...
Effects of rumen metabolite butyric acid on bovine skeletal muscle satellite cells proliferation, apoptosis and transcriptional states during myogenic differentiation [0.03%]
丁酸对骨骼肌卫星细胞增殖、凋亡及成肌分化过程中转录状态的影响研究
Xiao-Wei Wang,Yan-Ling Ding,Cheng-Long Li et al.
Xiao-Wei Wang et al.
Butyric acid, a pivotal short-chain fatty acid in rumen digestion, profoundly influences animal digestive and locomotor systems. Extensive research indicates its direct or indirect involvement in the growth and development of muscle and fat...
Physiological and metabolic effects of short-term dopamine reduction in healthy horses using a tyrosine hydroxylase inhibitor (alpha-methyl-para-tyrosine) [0.03%]
α-甲基-对酪胺(酪氨酸羟化酶抑制剂)短期减少健康马多巴胺的生理和代谢效应
Nicolas C Galinelli,Nicholas J Bamford,Madison L Erdody et al.
Nicolas C Galinelli et al.
Alpha-methyl-para-tyrosine (AMPT) is a reversible inhibitor of tyrosine hydroxylase, the rate-limiting enzyme in catecholamine synthesis. This study aimed to determine whether AMPT could reduce dopamine concentrations in horses. Six healthy...
Improving survival and growth of caprine preantral follicles cultured in medium commonly used for MSC: Role of oxidative stress regulation and epigenetic changes [0.03%]
用于间充质干细胞的培养基中山羊前囊泡的存活和生长的改善:氧化应激调节和表观遗传学改变的作用
Ana F B Silva,Laritza F Lima,Anna C A Ferreira et al.
Ana F B Silva et al.
This study evaluated the efficiency of in vitro culture of preantral follicles (PAF) in a commonly used medium for mesenchymal stem cell (MSC) culture. Parameters assessed included follicle survival, growth, stromal cell density, levels of ...
Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO4 in porcine ovarian granulosa cells [0.03%]
槲皮素对硫酸铜浓度过高诱导的猪卵泡颗粒细胞自噬和凋亡的影响
Nannan Qi,Binbin Wang,Wenwen Xing et al.
Nannan Qi et al.
Copper is a vital micronutrient necessary for the maintenance of physiological functions. However, excessive amounts can lead to organ damage. Porcine ovarian granulosa cells are damaged by a high concentration of CuSO4, which can reduce th...
Mio Kikuchi,Harutaka Murase,Kenichi Urata et al.
Mio Kikuchi et al.
Circulating microRNAs (miRNAs) are stable in body fluids and can serve as biomarkers for various diseases and physiological states. Although pregnancy-related miRNAs have been identified in various mammals, studies on parturition-related ci...