Associations of endocannabinoid serum concentrations with behavioral impulsivity and substance use in late childhood to early adolescence [0.03%]
内源大麻素浓度与晚童年期至少年期的行为冲动和物质使用的关系
Chase A Shankula,Ryan M Sullivan,Elizabeth A Stinson et al.
Chase A Shankula et al.
Objective: Adolescence is characterized by rapid neurobehavioral development. The endocannabinoid (eCB) system modulates several co-developing neurotransmitter systems and is well-implicated in preclinical substance use (...
Sex-based effectiveness in buprenorphine/naloxone and methadone treatment for opioid use disorder: Findings from the OPTIMA trial [0.03%]
基于性别的丁丙诺啡/纳洛酮和美沙酮治疗阿片类药物使用障碍有效性的研究：OPTIMA试验的结果
Christina McAnulty,Gabriel Bastien,Cédric Pek et al.
Christina McAnulty et al.
Introduction: Opioid use disorder (OUD) is a public health challenge globally. Few studies examine sex differences in opioid agonist therapy outcomes, especially in contexts of high potency opioid consumption. Clarifying ...
Impact of schedule V controlled substance classification of gabapentin on adult gabapentin-involved overdose rates, West Virginia, 2016-2019: A controlled time series analysis [0.03%]
加巴喷丁成人药物过量率在西弗吉尼亚州被列为五类受控物质的的影响：一项受控时间序列分析（2016-2019年）
Katherine Gora Combs,Juan M Hincapie-Castillo,Nabarun Dasgupta et al.
Katherine Gora Combs et al.
Objective: Assess the association between West Virginia's classification of gabapentin as a schedule V controlled substance and fatal overdoses involving gabapentin, relative to a control state. ...
Cigarette smoking, history of major depression and PTSD diagnosis are associated with metabolite levels in the left dorsolateral prefrontal cortex in those in treatment for alcohol use disorder [0.03%]
吸烟史、重度抑郁发作和创伤后应激障碍诊断与正在接受酒精使用障碍治疗的人在左背外侧前额叶皮层的代谢物水平有关
Timothy C Durazzo,Riley E Carolan,Lauren H Beauregard et al.
Timothy C Durazzo et al.
Background: Despite the known systemic health risks associated with cigarette smoking, research investigating the neurobiological consequences of smoking in those with alcohol use disorder (AUD) is minimal. This study com...
Dose and age matter: Xylazine prevents age-dependent fentanyl lethality in rats [0.03%]
剂量和年龄很重要：戊二醇胶黄素能预防大鼠年龄依赖性盐酸芬太尼致死
Julio D Zuarth-Gonzalez,Elmira Zolali,Yash Mehta et al.
Julio D Zuarth-Gonzalez et al.
Background: Xylazine, a veterinary sedative not approved for human use, has emerged as a common adulterant in North America's illicit opioid supply, e.g., detected in over 90% of Philadelphia's street samples. Preclinical...
Associations between daily pain severity and concurrent alcohol craving among women in early recovery following alcohol treatment [0.03%]
女性酒精戒断早期恢复期间每日疼痛严重程度与同时出现的酒精渴求之间的关联
Erin Ferguson,Jiwon Min,Cynthia L Battle et al.
Erin Ferguson et al.
Background: Rates of alcohol use disorder (AUD) for women are rising, and women remain more likely to experience serious alcohol-related harms and consequences compared to men. Pain may complicate AUD, as it often co-occu...
Factors associated with the development of systemic versus local infections in people who inject drugs [0.03%]
与注射毒品者发生全身感染和局部感染相关的因素
Reem Sabra,Hélène Donnadieu,Céline Eiden et al.
Reem Sabra et al.
Objectives: To describe bacterial infections among people who inject drugs (PWID) in France, identify factors associated with systemic infection and define patient groups based on demographic and consumption profiles. ...
Feasibility of continuous sleep and environmental monitoring in residential substance use recovery: Associations with mental health outcomes [0.03%]
连续睡眠和环境监测在住宅物质使用康复中的可行性：与心理健康结果的关联性研究
Kalina R Rossa,Shannon L Edmed,Dwayne L Mann et al.
Kalina R Rossa et al.
Introduction: Quality sleep is important for substance use recovery. Supporting and monitoring sleep during residential treatment poses challenges, but unobtrusive technologies like actigraphy or environmental sensors off...
Time-varying mediated effects of the nicotine patch on smoking before and after a quit attempt when it is added to varenicline and counseling [0.03%]
在伐尼克兰和咨询的基础上添加尼古丁贴片对尝试戒烟前后的吸烟者的时间变化中介效应
Nayoung Kim,Timothy B Baker,Donna L Coffman et al.
Nayoung Kim et al.
Background: Even with evidence-based treatment, most people who try to quit smoking return to regular smoking within weeks. Mediation analyses simultaneously test hypotheses about how treatments affect possible smoking de...
Measurement challenges in binge drinking research: Addressing sex and gender diversity in national surveys [0.03%]
关于滥饮酒研究中的测量问题：在国家级调查中解决性别多样性的方法
Sunday Azagba
Sunday Azagba
Background: Accurate measurement of binge drinking is essential for understanding population-level health disparities. However, national surveys commonly rely on binary sex-based thresholds, which may introduce classifica...