Missed opportunities for Hepatitis C Virus screening and care among persons hospitalized for injection-related infections [0.03%]
注射相关感染住院患者的丙型肝炎病毒感染筛查和治疗机会丢失分析
Keanan McGonigle,Jillian S Catalanotti,Sarah Kattakuzhy et al.
Keanan McGonigle et al.
Hospitalization provides an opportunity to improve the Hepatitis C Virus (HCV) cascade of care among people who inject drugs. Little is known about whether this potential opportunity is utilized. We conducted a retrospective chart review at...
Hippocampal volume alterations in opioid use disorder: Evidence for posterior vulnerability and heterogeneity [0.03%]
阿片类物质使用障碍中海马体积的改变：后部脆弱性和异质性的证据
Paul S Regier,Delaney McKinstry,Joel M Stein et al.
Paul S Regier et al.
Evidence is emerging that chronic exposure to opioids can impact brain structure, with preclinical studies demonstrating alterations in subcortical regions, including the hippocampus; however, corresponding evidence in humans remains limite...
Testing a social mechanism of recovery high schools: Peer affiliation as a mediator of substance use outcomes [0.03%]
恢复高中社交机制的检验：同伴认同感对物质使用结果的中介作用
Lauren M Berny,Emily A Hennessy,Andrew J Finch et al.
Lauren M Berny et al.
Purpose: Limited options for developmentally appropriate continuing care represent a critical barrier for youth in recovery. As one of the few options designed specifically for adolescents, recovery high schools (RHSs) wa...
Progress toward hepatitis C elimination among people who inject drugs in San Francisco, 2018 - 2024 [0.03%]
旧金山地区2018至2024年朝消除丙型肝炎目标迈进——注射毒品使用者群体的进展
Christopher J Hernandez,Bow Suprasert,Glenda Baguso et al.
Christopher J Hernandez et al.
Background: Hepatitis C virus (HCV) remains a major cause of liver-related morbidity and mortality, with people who inject drugs (PWID) disproportionately affected. San Francisco has implemented elimination efforts throug...
Dezocine-mediated reversal of sufentanil-induced respiratory depression and its mitigation of adverse reactions: A clinical investigation [0.03%]
Dezocine介导的苏芬太尼致呼吸抑制的逆转及其缓释副作用的临床研究
Yong-Kang Gui,Li-Fang Liu,Meng-Lei Shan et al.
Yong-Kang Gui et al.
Background: Respiratory depression (RD) is the most life-threatening adverse reaction associated with opioid drug use. However, previous studies have found that partial opioid receptor agonists can effectively reverse RD ...
Methcathinone self-administration decreases dopamine and serotonin transporter function in rats [0.03%]
美沙卡因自给减少大鼠多巴胺和血清素转运蛋白功能
Charlotte P Magee,Kathleen Nguyen,BaoMinh D Le et al.
Charlotte P Magee et al.
Objective: Methcathinone is a synthetic cathinone that has high misuse liability and produces its stimulant effects through acute actions on monoaminergic transporters, including the dopamine and serotonin transporters. W...
Estimating the daily milligrams of morphine equivalent of illicit fentanyl use in Los Angeles: Clinical and epidemiological implications [0.03%]
估算洛杉矶地区非法芬太尼使用的每日等量毫克吗啡用量：临床和流行病学意义
Morgan Godvin,Joseph R Friedman,Caitlin A Molina et al.
Morgan Godvin et al.
Introduction: The market shift from heroin to illicitly-manufactured-fentanyl in North America led to surging opioid mortality. However, limited information exists about the doses of illicit fentanyl regularly consumed. W...
Effects of virtual reality-based interventions on craving in substance use disorders: A systematic review and meta-analysis of randomized controlled trials [0.03%]
基于虚拟现实的干预措施对物质使用障碍患者渴望的影响：系统评价和meta分析
Jiayi Li,Feng Ding,Jiwei Chen et al.
Jiayi Li et al.
Objective: To systematically evaluate the efficacy of virtual reality-based interventions in reducing craving among individuals with substance use disorders. ...
Pilot randomized study of three digital models to train opioid use disorder counselors in community reinforcement and family training [0.03%]
社区强化和家庭培训治疗 opioid 使用障碍咨询师的三种数字模型训练模式的试点随机研究
Jane Macky,Calum Handley,Kimberly C Kirby et al.
Jane Macky et al.
Introduction: Community Reinforcement and Family Training (CRAFT) is an evidence-based approach that promotes family skills to encourage people with substance use disorders to seek treatment. To enhance scalable CRAFT imp...
Efficacy signals in a 12-week trial of clavulanic acid to decrease cocaine use [0.03%]
12周试验中使用克拉维酸降低可卡因成瘾有效性的信号反应
Joya Maser,Linda Callans,Daohai Yu et al.
Joya Maser et al.
Background: There is urgent need for effective medication to treat cocaine use disorder (CUD). Clavulanic acid (CLAV) is a clinical stage medication that has potential for treating CUD. ...