Safer supply deprescribing during a toxic drug poisoning crisis in Vancouver, Canada [0.03%]
加拿大温哥华有毒药物中毒危机期间更安全的供应链停止使用药物政策
Alexa Norton,Kanna Hayashi,Eric C Sayre et al.
Alexa Norton et al.
Background: Since 2016, more than 53,000 Canadians have died from exposure to the toxic unregulated drug supply. In 2020, the British Columbia government implemented a program in which pharmaceutical alternatives to toxic...
Perinatal smoking in mothers and fathers: Longitudinal associations with infant birth outcomes in the Triple B Pregnancy Cohort Study [0.03%]
母亲和父亲围产期吸烟与三联B孕期队列研究中的婴儿出生结局的纵向相关性分析
Emmelyn Weller,Stephanie R Aarsman,Samantha Teague et al.
Emmelyn Weller et al.
Background and aims: Maternal smoking in pregnancy is a risk factor for poorer infant health outcomes, yet knowledge on impacts of smoking in the preconception and periconception periods is limited, particularly in father...
Thanh T Lu,Johanna Catherine Maclean,Arnie Aldridge et al.
Thanh T Lu et al.
Aims: Climate change poses many threats, such as increased risks of hot or cold weather events to the health and well-being of Americans. Previous studies examined relationships between temperature exposure and physical o...
Buprenorphine initiation by a street medicine program is associated with reduced opioid-related emergency department utilization among people experiencing homelessness [0.03%]
街头医疗项目启动丁丙诺啡与减少无家可归者的阿片类药物相关急诊就诊有关
Cecilia R Wallace,Jasmine King,Timothy Nichols et al.
Cecilia R Wallace et al.
Objectives: People experiencing homelessness (PEH) are at increased risk for addiction, with substance use both a cause and response to homelessness. Street Medicine (SM) programs provide decentralized, low-barrier care t...
Co-use of alcohol and e-cigarettes and the role of social influences during drinking events among young adults: A day-level study [0.03%]
酒精与电子烟的共用及社交影响在饮酒活动中的作用：一项关于年轻人的日界研究
Siobhan N Perks,Suzanne M Colby,Melissa A Clark et al.
Siobhan N Perks et al.
Background: Alcohol and e-cigarettes are commonly used among young adults (YAs), and many co-use both substances. Social influences strongly predict the individual use of alcohol and e-cigarettes, but their role in co-use...
Youth's perception of parental limitation of youth screen time is associated with lower odds of nicotine vaping among US youth: Results from the 2024 National Survey on Drug Use and Health (NSDUH) [0.03%]
美国青年对家长限制屏幕时间看法与较低的尼古丁雾化几率有关：来自2024年《国家药物使用和健康调查》的结果
Juhan Lee,Delvon T Mattingly
Juhan Lee
Background: Youth media exposure is associated with vaping, while parental limitation of youth screen time may be associated with lower odds of youth vaping. Using nationally representative survey data, this study examine...
A pilot randomized feasibility clinical trial of intranasal vs. intravenous naloxone in pediatric opioid poisoning [0.03%]
儿科阿片类中毒患者鼻用纳洛酮与静脉注射纳洛酮疗效的试点随机可行性临床试验
Narges Gholami,Arne Kristian Skulberg,Fariba Farnaghi et al.
Narges Gholami et al.
Background: The opioid epidemic also affects children, yet treatment options for opioid poisoning in this population remain underexplored. This study evaluated the feasibility of a randomized trial comparing intranasal (I...
Assessing measurement bias in substance withdrawal symptoms attributable to childhood adversity and genetic liability [0.03%]
评估童年逆境和遗传易感性所致物质戒断症状的测量偏差
Angela Han,Jackson Soohoo,Joel Gelernter et al.
Angela Han et al.
Background: Substance withdrawal results from the abrupt cessation or reduction of substance use in physically dependent individuals. Diagnosis of withdrawal requires endorsing multiple substance-specific symptoms, implic...
Cannabinoid (CB) 1 receptor antagonists block fentanyl conditioned place preference but not fentanyl antinociception [0.03%]
cannabinoid (cb) 1受体拮抗剂可阻断喷他佐辛条件位置偏爱但不影响镇痛作用
Devin Morrisson,Evan C Smith,Dalal Alkhelb et al.
Devin Morrisson et al.
Background: Preclinical studies have found the cannabinoid (CB) 1 receptor inverse agonist/antagonist rimonabant and CB1 neutral antagonists (AM4113, AM6527) to attenuate the addiction-related behavioral effects of opioid...
Opioid use disorder and hospital readmission in the United States from 2010 to 2022: Primary reasons and the complex interplay of comorbid conditions [0.03%]
美国2010年至2022年阿片类药物使用障碍和住院再入院的主要原因及合并症的复杂相互作用
Fares Qeadan,Rose Thornquist,Ashlie McCunn et al.
Fares Qeadan et al.
Background: The opioid epidemic in the United States (U.S.) is a critical public health issue that has led to a sharp increase in opioid-related deaths, as well as significant implications for healthcare systems, includin...