Barriers and facilitators for preventing adverse drug reactions of long latency: a qualitative study [0.03%]
长期药物不良反应预防障碍及促进因素的定性研究
Liron Caplan,Leah M Haverhals
Liron Caplan
Objective: To understand the practices medical care providers and health care staff utilize in managing and preventing Adverse Drug Reactions of Long Latency (ADRLLs) among their patients on medications such as glucocorti...
The rosiglitazone decision process at FDA and EMA. What should we learn? [0.03%]
罗格列酮在FDA和EMA的决策历程。我们应当吸取什么经验？
Koen B Pouwels,Kees van Grootheest
Koen B Pouwels
In September 2010 the EMA decided to suspend the market authorisation of rosiglitazone, while the FDA decided to restrict the use of rosiglitazone. These actions were taken approximately 10 years after the introduction of rosiglitazone, bec...
Pharmacovigilance amongst patent medicine vendors (PMVs) in Ekiti state, Nigeria [0.03%]
尼日利亚埃基蒂州专利药品经销商中的药物警戒行为
Olufunsho Awodele,Adeyinka Adeniran,Deborah F Awodele
Olufunsho Awodele
With the current population of Nigeria and the limited number of trained health care providers, PMVs are inevitable and highly needed especially in the rural areas for the supply of drugs in treating minor illnesses. Thus, pharmacovigilance...
Kenneth Hartigan-Go
Kenneth Hartigan-Go
The medical doctor is sometimes called upon to serve in the courts as expert witness. The work is challenging and has serious implications for the legal and justice system. The outcome of a case may adversely affect the lives of real people...
Graham Dukes
Graham Dukes
In writing an expert report for any court or tribunal, account must be taken of that body's needs and where necessary of its strengths and weaknesses. The essential elements are truth, clarity and conciseness. The expert should indicate the...
I Ralph Edwards
I Ralph Edwards
Causality has been a topic of debate by philosophers, scientists, lawyers and for centuries. It is essential to define as precisely as possible all steps in the logical chain of events, since each may strengthen or confound an argument. Alm...
Jerry Labadie
Jerry Labadie
Identification of harm in the form of adverse drug reactions that are caused by counterfeit or other substandard medicinal products by application of standard pharmacovigillance methods of registration, analysis and investigation could be f...
Nav Persaud,David Healy
Nav Persaud
Until recently epidemiological evidence was not regarded as helpful in determining cause and effect. It generated associations that then had to be explained in terms of bio-mechanisms and applied to individual patients. A series of legal ca...
Case histories as evidence [0.03%]
案例作为证据
Andrew Herxheimer,David Healy,David B Menkes
Andrew Herxheimer
In courts case histories play a central part when a crime may have resulted from an effect of a prescribed drug; in civil cases where a person may have suffered damage from a drug; and in coroners' enquiries into the cause of unexplained de...
R E Ferner
R E Ferner
Laboratory evidence of the presence and concentration of a drug in a person who has come to harm is often helpful in forensic pharmacology, and may be crucial. However, its value depends on two critical interpretations by the expert. First,...