Comparison of hematological adverse reactions in patients with epilepsy on monotherapy versus polytherapy [0.03%]
单药与多药治疗癫痫患者的血液学不良反应比较分析
Ogunjimi Luqman,Ogunjimi Olabisi,Kasali Adeola et al.
Ogunjimi Luqman et al.
BackgroundThis study compared the effects of anti-seizure medication (ASM) monotherapy and polytherapy on hematological parameters in patients with epilepsy (PWE).ObjectiveTo compare hematological parameters and derived inflammatory indices...
Drug-induced methemoglobinemia in a child with comorbidity and polypragmasia: Case report [0.03%]
合并多种疾病和多种药物治疗的儿童药物所致高铁血红蛋白血症1例报告
Alina B Strok,Maria N Kostyleva,Anna V Kostina
Alina B Strok
Background: The article describes a case of methemoglobinemia in a 4-year-old child with nephrotic syndrome with simultaneous use of therapeutic doses of three drugs that cause methemoglobinemia: lidocaine (topically), benzocaine (topically...
Neuropsychiatric adverse events associated with lorlatinib in ALK-positive NSCLC [0.03%]
lorlatinib治疗阳性NSCLC的精神神经不良事件
Eleonora Castellana,Maria Rachele Chiappetta
Eleonora Castellana
BackgroundLorlatinib, a third-generation ALK/ROS1 inhibitor, is highly effective in ALK-positive non-small-cell lung cancer (NSCLC), particularly for intracranial disease. It is associated with a distinctive neuropsychiatric toxicity profil...
Stephen J Taylor
Stephen J Taylor
National guidance advises post-procedure pH or X-ray checks to prevent use of tubes misplaced in the respiratory tract; this occurs in 0.017% of placements. However, post-procedure checks cannot prevent the in-procedure pneumothorax in 0.43...
Chronic venlafaxine ingestion inducing bluish oral hyperpigmentation with dysgeusia and dysphagia: A case report [0.03%]
长期服用文拉法辛引起口腔蓝灰色色素沉着伴味觉异常和吞咽困难的病例报告
Yamini Ajmera,Karandeep Paul,Prasun Chatterjee
Yamini Ajmera
BackgroundMedication-induced oral hyperpigmentation represents an adverse drug reaction characterized by variable latency and unclear mechanism. Diagnosis is particularly challenging in older adults due to non-specific symptoms, multiple co...
How I contributed to Cochrane Crowd and why it matters for evidence synthesis [0.03%]
我如何参与Cochrane Crowd以及它为何对证据综合重要
Vladimir Kataev
Vladimir Kataev
Robust evidence depends on disciplined methods rather than slogans. This commentary draws on my experience with Cochrane Crowd to show how brief, well-structured micro-tasks can strengthen the evidence pipeline. Two features are central: th...
Clinical profile of healthcare employees with needlestick and sharps injuries and infectious body fluid exposure in tertiary care hospitals in southern India [0.03%]
印度南部三级医院医务人员针刺和锐器伤及接触感染性体液的职业暴露临床特征
Nitin Joseph,Jithin Surendran,Ayandeep Baruah et al.
Nitin Joseph et al.
BackgroundNeedle-stick and sharps injuries (NSSIs) are major occupational hazards faced by healthcare employees (HCEs) worldwide.ObjectivesThis study aimed to assess trends of NSSIs among HCEs and their exposure to other infected body fluid...
Role of pathological autopsy in determining the cause of death in cases of unexpected clinical deterioration or medical incidents [0.03%]
病理尸检在病情突然恶化或医疗意外死因认定中的作用
Sachi Miyashita,Tadashi Kamio,Hiroshi Koyama et al.
Sachi Miyashita et al.
BackgroundThe extent to which autopsies are conducted and their role in determining the cause of death has not been sufficiently examined. We aimed to evaluate the contribution of autopsy in determining the cause of death in cases of unexpe...
Proactive risk analysis in chemotherapy nursing processes: A systematic review of FMEA/FMECA applications [0.03%]
化疗护理过程中的主动风险管理：关于FMEA/FMECA应用的系统综述
Gennaro Laus,Giuseppe Bertozzi,Aldo Di Fazio et al.
Gennaro Laus et al.
BackgroundChemotherapy management is a high-risk process, especially in oncology nursing, where errors can have serious consequences. Proactive risk analysis tools such as Failure Mode and Effects Analysis (FMEA) and its variant with Critic...
Strengthening pharmacovigilance for herbal medicines in Nigeria: An urgent health systems challenge [0.03%]
尼日利亚草药药品的强化警戒：亟待解决的卫生系统挑战
David Ololade Atanda,Oluwabukunmi Deborah Ayoola,Esther Oluwasemipe Adegunloye et al.
David Ololade Atanda et al.