Behavior, nutrition and lifestyle in a comprehensive health and disease paradigm: skills and knowledge for a predictive, preventive and personalized medicine [0.03%]
行为、营养和生活方式在综合健康与疾病范式中的作用：预测性、预防性和个性化医学所需的技能和知识
Guglielmo M Trovato
Guglielmo M Trovato
Health and disease of individuals and of populations are the result of three groups of risk factors: genetics, environment and behavior. Assessment, interventions and tailored changes are possible with integrated approaches more effective i...
Methods for analysis of the cancer microenvironment and their potential for disease prediction, monitoring and personalized treatments [0.03%]
癌症微环境分析方法及其在疾病预测、监测和个性化治疗中的潜在应用
Carl-Magnus Clausson,Ida Grundberg,Irene Weibrecht et al.
Carl-Magnus Clausson et al.
A tumor does not consist of a homogenous population of cancer cells. Therefore, to understand cancer, the tumor microenvironment and the interplay between the different cell types present in the tumor has to be taken into account, and how t...
Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer [0.03%]
打开潘多拉的盒子：非小细胞肺癌的个性化治疗诱导癌细胞凋亡
Dean A Fennell,Charles Swanton
Dean A Fennell
Evasion of apoptosis is a hallmark of tumorigenesis and a recognised cause of multidrug resistance. Over the last decade, insights into how apoptosis might be exploited in non-small cell lung cancer (NSCLC) and how cancer therapeutics might...
Judita Kinkorová,Ondřej Topolčan
Judita Kinkorová
The healthcare system in the Czech Republic underwent and still is undergoing dramatic changes since the Velvet revolution in 1989. History of the Czech healthcare system, main healthcare laws, and the current status of healthcare documente...
Personalization of prostate cancer prevention and therapy: are clinically qualified biomarkers in the horizon? [0.03%]
前列腺癌的预防和治疗个性化：合格的临床生物标志物即将出现？
Timothy A Yap,Charles Swanton,Johann S de Bono
Timothy A Yap
Prostate cancer remains the most common malignancy among men and the second leading cause of male cancer-related mortality. Death from this disease is invariably due to resistance to androgen deprivation therapy. Our improved understanding ...
Exercise in multiple sclerosis -- an integral component of disease management [0.03%]
多发性硬化运动康复--疾病管理的重要环节
Andrea Döring,Caspar F Pfueller,Friedemann Paul et al.
Andrea Döring et al.
Multiple sclerosis (MS) is the most common chronic inflammatory disorder of the central nervous system (CNS) in young adults. The disease causes a wide range of symptoms depending on the localization and characteristics of the CNS pathology...
Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity [0.03%]
预防性、预测性和个性化的肾细胞癌医学递送的挑战：肿瘤异质性的问题
Rosalie Fisher,James Larkin,Charles Swanton
Rosalie Fisher
Recent years have seen major advances in the management of metastatic renal cell carcinoma (mRCC). The tyrosine kinase and mammalian target of rapamycin inhibitors have resulted in disease control and improved survival for many patients wit...