On the emerging role of body culture and individualised exercise training for PPPM [0.03%]
身体文化在预防、治疗和康复中的新兴作用及个性化运动训练的发展趋势
Henning Boecker
Henning Boecker
Head and neck cancer: effective prevention in youth and predictive diagnostics for personalised treatment strategies according to biological differences [0.03%]
头颈肿瘤：青年时期有效的预防以及根据生物学差异进行个性化治疗策略的预测性诊断
Andreas Dietz,Gunnar Wichmann
Andreas Dietz
This article focuses on squamous cell carcinomas of the larynx, pharynx and oral cavity which count nearly 90% of the head and neck squamous cell carcinomas (HNSCC). Individual susceptibility depends on an individually given genetic backgro...
Personalised medicine in paediatrics: individualising treatment in children with rare neurological diseases [0.03%]
儿科的个性化医疗：针对罕见神经疾病的儿童个体化治疗
Maurizio Scarpa,Adriana Ceci,Rosella Tomanin et al.
Maurizio Scarpa et al.
The development of personalised medicine is of considerable importance for paediatric patient populations, and represents a move away from the use of treatment dosages based on experience with the same compounds in adults. Currently, howeve...
Pathophysiology of perinatal asphyxia: can we predict and improve individual outcomes? [0.03%]
围产期窒息的病理生理学：能否预测和改善个体结局？
Paola Morales,Diego Bustamante,Pablo Espina-Marchant et al.
Paola Morales et al.
Perinatal asphyxia occurs still with great incidence whenever delivery is prolonged, despite improvements in perinatal care. After asphyxia, infants can suffer from short- to long-term neurological sequelae, their severity depend upon the e...
Birth asphyxia as the major complication in newborns: moving towards improved individual outcomes by prediction, targeted prevention and tailored medical care [0.03%]
新生儿缺氧是主要并发症：通过预测、针对性预防和个性化医疗以改善个体预后
Olga Golubnitschaja,Kristina Yeghiazaryan,Melanie Cebioglu et al.
Olga Golubnitschaja et al.
Perinatal Asphyxia-oxygen deficit at delivery-can lead to severe hypoxic ischaemic organ damage in newborns followed by a fatal outcome or severe life-long pathologies. The severe insults often cause neurodegenerative diseases, mental retar...
Prediction, prevention and personalisation of medication for the prenatal period: genetic prenatal tests for both rare and common diseases [0.03%]
产前预测、预防及药物个性化：罕见病与常见病的产前基因检测
Munis Dundar,Asli Subasioglu Uzak,Murat Erdogan et al.
Munis Dundar et al.
Genetic testing usually helps physicians to determine possible genetic diseases in unborn babies, genetic disorders of patients and the carriers who might pass the mutant gene on to their children. They are performed on blood, tissues or ot...
Genetic testing: predictive value of genotyping for diagnosis and management of disease [0.03%]
基因检测：基因分型在疾病诊断和治疗中的预测价值
Meral Ozgüç
Meral Ozgüç
This article describes predictive, preventive value of genetic tests and the implication of the use of testing for personalized treatment. This year marks the 10th anniversity of publishing of the sequence of the human genome. One important...
Non-invasive prenatal diagnosis using cell-free fetal nucleic acids in maternal plasma: Progress overview beyond predictive and personalized diagnosis [0.03%]
无创产前诊断：母体血浆游离胎儿核糖核酸的非侵入性产前诊断技术及其在预测和个体化医学之外的应用进展概述
Georgia Tounta,Aggeliki Kolialexi,Nikolas Papantoniou et al.
Georgia Tounta et al.
The discovery of circulating cell-free fetal DNA (cffDNA) in maternal plasma allowed for the development of alternative methodologies that may facilitate safe non-invasive prenatal diagnosis (NIPD). The low concentration of cffDNA in matern...
Biomarker development for non-invasive prenatal diagnosis of fetal aneuploidies: predictive reliability and potential clinical application [0.03%]
无创产前诊断胎儿非整倍体的生物标记物开发：预测可靠性与潜在临床应用
Aggeliki Kolialexi,Athanasios K Anagnostopoulos,Georgia Tounta et al.
Aggeliki Kolialexi et al.
Current non-invasive prenatal diagnosis for fetal aneuploidies is based on biochemical and ultrasound markers and needs to be improved in order to reduce the number of pregnant women subjected to invasive diagnostic procedures. Proteomic te...
Application of proteomics for the identification of biomarkers in amniotic fluid: are we ready to provide a reliable prediction? [0.03%]
蛋白质组学在羊水生物标志物鉴定中的应用：我们能提供可靠的预测吗？
George Th Tsangaris,Athanasios K Anagnostopoulos,Georgia Tounta et al.
George Th Tsangaris et al.
Proteomics-based identification of biomarkers for fetal abnormalities and pregnancy complications in amniotic fluid (AF) has made significant progress in the past 5 years. This is attributed mainly to advances in mass spectrometry-based pro...