Herbert H Lipowsky,Gerard Nash
Herbert H Lipowsky
Using cell monolayer rheology to probe average single cell mechanical properties [0.03%]
利用细胞单层流变学探测平均单细胞机械性能
Mathias Sander,Julia Flesch,Albrecht Ott
Mathias Sander
The cell monolayer rheology technique consists of a commercial rotational rheometer that probes the mechanical properties of a monolayer of isolated cells. So far we have described properties of an entire monolayer. In this short communicat...
Hemodynamics of the renal artery ostia with implications for their structural development and efficiency of flow [0.03%]
肾动脉开口的血流动力学及其对结构发育和流动效率的影响
William H McIntosh,Mesude Ozturk,Linden A Down et al.
William H McIntosh et al.
Background: Energy losses at tube or blood vessel orifices depend on the extent of flare as measured by the dimensionless ratio of the fillet radius of curvature to diameter (r/D). ...
Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force [0.03%]
心房利钠肽通过减少细胞变形和抗脱落力来下调中性粒细胞在炎症内皮上的募集作用
Vasilios A Morikis,Chris Radecke,Yanyan Jiang et al.
Vasilios A Morikis et al.
Background: Recombinant atrial natriuretic peptide (ANP) is administered in patients with acute heart failure in Japan to improve renal function and hemodynamics, but its anti-inflammatory effect on activated leukocytes m...
In microfluidico: Recreating in vivo hemodynamics using miniaturized devices [0.03%]
微流体中的仿生血管流动的微型装置研究进展
Shu Zhu,Bradley A Herbig,Ruizhi Li et al.
Shu Zhu et al.
Microfluidic devices create precisely controlled reactive blood flows and typically involve: (i) validated anticoagulation/pharmacology protocols, (ii) defined reactive surfaces, (iii) defined flow-transport regimes, and (iv) optical imagin...
Regulation of L-selectin-dependent hydrodynamic shear thresholding by leukocyte deformability and shear dependent bond number [0.03%]
白细胞变形性和剪切应力依赖性结合数对L-选择素介导的流体剪切应力阈值作用的调节机制研究
Christopher D Paschall,Alexander L Klibanov,Michael B Lawrence
Christopher D Paschall
Background: During inflammation leukocyte attachment to the blood vessel wall is augmented by capture of near-wall flowing leukocytes by previously adherent leukocytes. Adhesive interactions between flowing and adherent l...
Role of matrix metalloproteases in the kinetics of leukocyte-endothelial adhesion in post-capillary venules [0.03%]
基质金属蛋白酶在微静脉中白细胞内皮粘附动力学中的作用
Herbert H Lipowsky,Anne Lescanic,Rachna Sah
Herbert H Lipowsky
Background: The endothelial glycocalyx serves as a barrier to leukocyte (WBC)-endothelium (EC) adhesion. Shedding of glycans, by matrix metalloproteases (MMPs) exposes EC integrin receptors to facilitate firm adhesion. Ho...
Role of fluid shear stress in regulating VWF structure, function and related blood disorders [0.03%]
流体剪切应力在调节vWF结构、功能及相关血液紊乱方面的角色
Shobhit Gogia,Sriram Neelamegham
Shobhit Gogia
Von Willebrand factor (VWF) is the largest glycoprotein in blood. It plays a crucial role in primary hemostasis via its binding interaction with platelet and endothelial cell surface receptors, other blood proteins and extra-cellular matrix...
Proteolytic receptor cleavage in the pathogenesis of blood rheology and co-morbidities in metabolic syndrome. Early forms of autodigestion [0.03%]
代谢综合征血流变学及并发症发病中的蛋白酶受体切割作用早期自身消化的形式
Rafi Mazor,Geert W Schmid-Schönbein
Rafi Mazor
Abnormal blood rheological properties seldom occur in isolation and instead are accompanied by other complications, often designated as co-morbidities. In the metabolic syndrome with complications like hypertension, diabetes and lack of nor...
Marc Herant,Micah Dembo
Marc Herant
Background: The processes of cell spreading and crawling are frequently associated with mysterious waves and ruffling cycles of the leading edge. Objectiv...