The Human Microbiome and Child Growth - First 1000 Days and Beyond [0.03%]
人类微生态与儿童生长发育——从生命的头1000天到未来
Ruairi C Robertson,Amee R Manges,B Brett Finlay et al.
Ruairi C Robertson et al.
The assembly of microbial communities within the gastrointestinal tract during early life plays a critical role in immune, endocrine, metabolic, and other host developmental pathways. Environmental insults during this period, such as food i...
David G Welkie,Benjamin E Rubin,Spencer Diamond et al.
David G Welkie et al.
Cyanobacteria are photosynthetic prokaryotes that are influential in global geochemistry and are promising candidates for industrial applications. Because the livelihood of cyanobacteria is directly dependent upon light, a comprehensive und...
Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection [0.03%]
真菌病原体中的记忆促进免疫逃避、定殖和感染
Alistair J P Brown,Neil A R Gow,Adilia Warris et al.
Alistair J P Brown et al.
By analogy with Pavlov's dogs, certain pathogens have evolved anticipatory behaviours that exploit specific signals in the human host to prepare themselves against imminent host challenges. This adaptive prediction, a type of history-depend...
Jimmy T Trinh,Lanying Zeng
Jimmy T Trinh
There are many strategies by which cell fates are decided. In one intriguing case, viruses communicate via the quorum-sensing-like 'arbitrium' system to bias infection outcomes. Through elucidating the detailed molecular mechanisms of such ...
Helene Botella,Julien Vaubourgeix
Helene Botella
Fluorescent amino acid analogs have proven to be useful tools for studying the dynamics of peptidoglycan metabolism. García-Heredia and colleagues showed that their route of incorporation differs depending on the adjunct fluorophore and ap...
Contamination in Low Microbial Biomass Microbiome Studies: Issues and Recommendations [0.03%]
低微生物群研究中的污染问题及建议措施
Raphael Eisenhofer,Jeremiah J Minich,Clarisse Marotz et al.
Raphael Eisenhofer et al.
Next-generation sequencing approaches in microbiome research have allowed surveys of microbial communities, their genomes, and their functions with higher sensitivity than ever before. However, this sensitivity is a double-edged sword becau...
MicroRNAs at the Host-Bacteria Interface: Host Defense or Bacterial Offense [0.03%]
宿主-细菌界面的微小RNA：对抗入侵还是防御感染？
Carmen Aguilar,Miguel Mano,Ana Eulalio
Carmen Aguilar
MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional regulators of gene expression. They are currently recognized for their important role in the intricate interaction between host and bacterial pathogens, ei...
Stanton B Gelvin
Stanton B Gelvin
Agrobacterium transfers T-DNA and several virulence effector proteins to plant cells. It is not known how and where T-complexes containing these components are assembled. A new study suggests that T-complexes form on the plant plasma membra...
Xu Zhang,Tingting Luo,Yongyi Shen
Xu Zhang
The H7N9 virus has caused five waves of human infections since 2013. However, human infections have almost disappeared in the past year. In a recent study, Shi et al. revealed that the usage of a bivalent H5/H7 vaccine successfully prevente...
Vladimír Hampl,Ivan Čepička,Marek Eliáš
Vladimír Hampl
Arguments based on cell energetics favour the view that a mitochondrion capable of oxidative phosphorylation was a prerequisite for the evolution of other features of the eukaryotic cell, including increased volume, genome size and, eventua...