Vibrio cholerae [0.03%]
霍乱弧菌
Soo Hun Yoon,Christopher M Waters
Soo Hun Yoon
CRISPR-Directed Microbiome Manipulation across the Food Supply Chain [0.03%]
食品供应链中 CRISPR 指导的微生物组操控技术
Rodolphe Barrangou,Richard A Notebaart
Rodolphe Barrangou
The advent of CRISPR-based technologies has revolutionized genetics over the past decade, and genome editing is now widely implemented for diverse medical and agricultural applications, such as correcting genetic disorders and improving cro...
Mira Laajala,Varpu Marjomäki
Mira Laajala
It has remained a puzzle why infants, during the first weeks of life, are especially prone to enterovirus infections. New work (Proc. Natl. Acad. Sci. U. S. A. 2019;116: 3758-3763) shines light on this matter by showing that the neonatal Fc...
Bacillus subtilis [0.03%]
枯草芽孢杆菌
Ákos T Kovács
Ákos T Kovács
Joshua Ladau,Emiley A Eloe-Fadrosh
Joshua Ladau
Microbial communities play a major role in disease, biogeochemical cycling, agriculture, and bioremediation. However, identifying the ecological processes that govern microbial community assembly and disentangling the relative impacts of th...
Mobilization of Microbiota Commensals and Their Bacteriocins for Therapeutics [0.03%]
调动共生微生物及其细菌素用于治疗
Pascal Hols,Laura Ledesma-García,Philippe Gabant et al.
Pascal Hols et al.
With the specter of resurgence of pathogens due to the propagation of antibiotic-resistance genes, innovative antimicrobial strategies are needed. In this review, we summarize the beneficial aspects of bacteriocins, a set of miscellaneous p...
Nutrient Availability and Metabolism Affect the Stability of Coral-Symbiodiniaceae Symbioses [0.03%]
养分的可获得性和代谢影响珊瑚-粘体藻共生关系的稳定性
Luke A Morris,Christian R Voolstra,Kate M Quigley et al.
Luke A Morris et al.
Coral reefs rely upon the highly optimized coral-Symbiodiniaceae symbiosis, making them sensitive to environmental change and susceptible to anthropogenic stress. Coral bleaching is predominantly attributed to photo-oxidative stress, yet nu...
The Promise of Long-Acting Antiretroviral Therapies: From Need to Manufacture [0.03%]
长效抗逆转录病毒疗法：从需求到生产
Howard E Gendelman,JoEllyn McMillan,Aditya N Bade et al.
Howard E Gendelman et al.
Antiretroviral therapy has transformed human immunodeficiency virus infections from certain death to a manageable chronic disease. Achieving strict adherence to drug regimens that limit toxicities and viral resistance is an achievable goal....
Feng Wen,Xiu-Feng Wan
Feng Wen
Influenza virus neuraminidase cleaves sialic acid groups from cell glycoproteins, enabling release of the virus from host cells. Neuraminidase also contributes to virus binding to the sialic acid groups of cell glycoproteins, which could co...
Experimental Evolution as a Tool to Investigate Natural Processes and Molecular Functions [0.03%]
实验进化研究在探究自然过程和分子功能方面的应用与挑战
Philippe Remigi,Catherine Masson-Boivin,Eduardo P C Rocha
Philippe Remigi
The experimental evolution (EE) of microbes has allowed evolutionary biologists to examine adaptive processes in real time, generating novel insights into fundamental laws of evolution. Less appreciated is the potential of this approach to ...