Bethany A Horsburgh,Sarah Palmer
Bethany A Horsburgh
New strategies to eliminate persistent HIV-1 during therapy will benefit from animal models, such as non-human primates infected with simian immunodeficiency viruses (SIV) or chimeras (SHIV). Understanding the genetic composition of SIV and...
Bacterial Amyloids: The Link between Bacterial Infections and Autoimmunity [0.03%]
细菌淀粉样蛋白：细菌感染与自身免疫之间的联系
Lauren Nicastro,Çagla Tükel
Lauren Nicastro
Molecular mimicry is a common mechanism used by many bacteria to evade immune responses. In recent years, it has become evident that bacteria also decorate the extracellular matrix (ECM) of their biofilms with molecules that resemble those ...
Cong Gao,Peng Xu,Chao Ye et al.
Cong Gao et al.
Rapid advances in DNA synthesis, genetic manipulation, and biosensors have greatly improved the ability to engineer microorganisms with complex functions. By accurately integrating quality biosensors and complex genetic circuits, recently e...
Maika S Deffieu,Raphael Gaudin
Maika S Deffieu
Although important breakthroughs in our understanding of the hepatitis B virus (HBV) life cycle have been made since the discovery of its main entry factor, the spatiotemporal dynamics of HBV-host interactions remains understudied. Here, we...
Dennis Claessen,Jeff Errington
Dennis Claessen
The cell wall is a surface layer located outside the cell membrane of almost all bacteria; it protects cells from environmental stresses and gives them their typical shape. The cell wall is highly conserved in bacteria and is the target for...
Stephanie Fulaz,Stefania Vitale,Laura Quinn et al.
Stephanie Fulaz et al.
The negative consequences of biofilms are widely reported. A defining feature of biofilms is the extracellular matrix, a complex mixture of biomacromolecules, termed EPS, which contributes to reduced antimicrobial susceptibility. EPS target...
Scedosporium apiospermum [0.03%]
斯卡多孢子菌苹果毛孢菌
Jean-Philippe Bouchara,Nicolas Papon
Jean-Philippe Bouchara
The MSCRAMM Family of Cell-Wall-Anchored Surface Proteins of Gram-Positive Cocci [0.03%]
革氏阳性球菌细胞壁结合型表面蛋白MSCRAMM家族
Timothy J Foster
Timothy J Foster
The microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) are a family of proteins that are defined by the presence of two adjacent IgG-like folded subdomains. These promote binding to ligands by mechanisms that invo...
Katelyn C Cook,Jorge A Moreno,Pierre M Jean Beltran et al.
Katelyn C Cook et al.
Peroxisomes are multifunctional organelles with roles in cellular metabolism, cytotoxicity, and signaling. The plastic nature of these organelles allows them to respond to diverse biological processes, such as virus infections, by remodelin...
Acid Fasting: Modulation of Mycobacterium tuberculosis Metabolism at Acidic pH [0.03%]
酸饥饿：酸性pH下调控结核分枝杆菌代谢
Jacob J Baker,Shelby J Dechow,Robert B Abramovitch
Jacob J Baker
Mycobacterium tuberculosis (Mtb) senses and adapts to acidic host environments during the course of pathogenesis. Mutants defective in acidic pH-dependent adaptations are often attenuated during macrophage or animal infections, supporting t...