Assessing the Potential for Staphylococcus aureus to Evolve Resistance to XF-73 [0.03%]
评估金黄色葡萄球菌进化出对XF-73耐药性的潜能
R Craig MacLean
R Craig MacLean
Nicholas S Sokol,Irene L G Newton
Nicholas S Sokol
Interactions between the eukaryotic host, microbiome members, and invading pathogens help to shape disease outcomes. Using the Drosophila model, Fast et al. identified that Vibrio cholerae acts to inhibit epithelial renewal through complex ...
Lucie Gallot-Lavallée,John M Archibald
Lucie Gallot-Lavallée
Phagocytosis - cell ingestion - is an important process confined to eukaryotes. Or is it? Shiratori et al. have discovered the existence of phagocytosis in a planctomycete bacterium, raising new questions about the significance of phagotrop...
J Claire Hoving,Gordon D Brown,Beatriz L Gómez et al.
J Claire Hoving et al.
Serious fungal infections continue to devastate people living with HIV and remain a leading cause of infection-related deaths in this population, second only to tuberculosis. The third AIDS-related mycoses workshop updated progress in the f...
Herpes Simplex Virus-1 in the Brain: The Dark Side of a Sneaky Infection [0.03%]
潜行感染的阴暗面——I型单纯疱疹病毒在脑中的危害
Maria Elena Marcocci,Giorgia Napoletani,Virginia Protto et al.
Maria Elena Marcocci et al.
Herpes simplex virus-1 (HSV-1) establishes latency preferentially in sensory neurons of peripheral ganglia. A variety of stresses can induce recurrent reactivations of the virus, which spreads and then actively replicates to the site of pri...
Erin E Price,Jeffrey M Boyd
Erin E Price
The acquisition of metal ions and the proper maturation of holo-metalloproteins are essential processes for all organisms. However, metal ion homeostasis is a double-edged sword. A cytosolic accumulation of metal ions can lead to mismetalla...
Lara Jochum,Bärbel Stecher
Lara Jochum
An increasing number of microorganisms are classified as 'pathobionts' (i.e., organisms that can cause harm under certain circumstances) but there exist no universally used criteria for this definition. In particular, the term is often used...
Michiel H In t Zandt,Susanne Liebner,Cornelia U Welte
Michiel H In t Zandt
Permafrost covers a quarter of the northern hemisphere land surface and contains twice the amount of carbon that is currently present in the atmosphere. Future climate change is expected to reduce its near-surface cover by over 90% by the e...
Parasexual and Sexual Reproduction in Arbuscular Mycorrhizal Fungi: Room for Both [0.03%]
丛枝菌根真菌的半卵式和有性繁殖:两者兼而有之的空间
Gökalp Yildirir,Mathu Malar C,Vasilis Kokkoris et al.
Gökalp Yildirir et al.
Arbuscular mycorrhizal fungi (AMF) harbor thousands of nuclei in a large syncytium at all times. Although mating processes have not been observed in AMF, their cells and genomes show many signatures of sexual reproduction. Here, we describe...
C J E Metcalf,A Wesolowski,A K Winter et al.
C J E Metcalf et al.
Measles vaccination is a public health 'best buy', with the highest cost of illness averted of any vaccine-preventable disease (Ozawa et al., Bull. WHO 2017;95:629). In recent decades, substantial reductions have been made in the number of ...