Bacterial genome structural variation: prevalence, mechanisms, and consequences [0.03%]
细菌基因组结构变异：流行率、机制和影响
Emma V Waters,Sarah K Cameron,Gemma C Langridge et al.
Emma V Waters et al.
A vast number of bacterial genome sequences are publicly available. However, the majority were generated using short-read sequencing, producing fragmented assemblies. Long-read sequencing can generate closed assemblies, and they reveal that...
Terence K Tutumlu,Cédric Dollé,Katharina Kusejko et al.
Terence K Tutumlu et al.
Mycobacteria have coevolved with humans over millennia, leaving profound imprints on our immune systems. Beyond active disease, their exposure may exert immunomodulatory effects, including allergy modulation and heterologous protection agai...
The microbiota shapes the life trajectory of mucosal-associated invariant T cells [0.03%]
菌群塑造粘膜相关不变T细胞的生命历程
Yan-Ruide Li,Xinyuan Shen,Yichen Zhu et al.
Yan-Ruide Li et al.
Mucosal-associated invariant T (MAIT) cells are innate-like T cells predominantly located in barrier tissues such as the lung, liver, skin, and colon. These cells recognize metabolites derived from the riboflavin biosynthetic pathway, which...
9th International Conference on Clinical Metagenomics (ICCMg9): meeting report [0.03%]
第九届国际临床元基因组学会议(ICCMg9) 报道会
Etienne Ruppé,Vladimir Lazarevic,Jacques Schrenzel
Etienne Ruppé
Bacteriophages as important considerations for mycorrhizal symbioses in our changing world [0.03%]
噬菌体作为根际中重要影响子囊菌共生关系的因素之一在变化中的世界扮演着重要的角色
Louis Berrios
Louis Berrios
Bacteriophages, bacteria, and mycorrhizal fungi are key members of plant microbiomes, yet connections among them remain unexplored. This forum article highlights the potential importance of bacteriophage knock-on effects in mycorrhizal ecol...
Strengthening arbovirus surveillance: bridging gaps for global health preparedness [0.03%]
加强虫媒病毒监测：弥合差距 促进全球卫生准备
Eleonora Cella,Mónica V Cunha,Luiz Carlos Junior Alcantara et al.
Eleonora Cella et al.
Despite significant advancements in arbovirus research, contributions remain disproportionately focused on regions with reported major outbreaks of diseases such as dengue, Zika, and chikungunya. This bias risks neglecting potentially criti...
Benjamin H Good,Ami S Bhatt,Michael J McDonald
Benjamin H Good
Research on horizontal gene transfer (HGT) has surged over the past two decades, revealing its critical role in accelerating evolutionary rates, facilitating adaptive innovations, and shaping pangenomes. Recent experimental and theoretical ...
How hepatitis E virus invades hepatocytes: the mystery of viral entry [0.03%]
戊型肝炎病毒如何侵入肝细胞：揭秘病毒入侵机制
Yannick Brüggemann,Nicola Frericks,Emely Richter et al.
Yannick Brüggemann et al.
Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis globally. HEV infections can progress to chronic disease in immunocompromised individuals and may also cause extrahepatic complications. By contrast to other hepatitis vi...
Brajesh K Singh,Gaofei Jiang,Zhong Wei et al.
Brajesh K Singh et al.
Healthy soil is vital for ecosystem sustainability and global food security. However, anthropogenic activities that promote intensive agriculture, landscape and biodiversity homogenization, and climate change disrupt soil health. The soil m...
Yanjun Kou,Naweed I Naqvi,Zeng Tao
Yanjun Kou
RNA modifications have been revealed by epitranscriptomics to play crucial roles in diverse biological processes. Nevertheless, data regarding RNA modifications during plant-pathogen interaction remain scarce. Recently, several studies have...