Allyson N X Choi,Duane J Gubler,Eng Eong Ooi
Allyson N X Choi
Dengue is an acute mosquito-borne viral disease widespread throughout tropical regions. Cyclical epidemics on top of high endemic dengue incidence strain many healthcare systems. While low population immunity to the four dengue viruses (DEN...
Amir Fromm,Talia S Shaler,Frank O Aylward et al.
Amir Fromm et al.
Viral infections of marine microbes greatly impact ecological and biogeochemical processes. Typically, these host-virus interactions are studied at the population level using bulk transcriptomics, which presents a population-averaged perspe...
Josie Elliott,Anne Chevallereau
Josie Elliott
In nature, phages frequently coinfect bacteria, leading to inter-species competition. Furthermore, phage therapy often involves using a cocktail of different species to circumvent bacterial resistance. Bürkle et al. investigated the compet...
Zhong Wei,Shaohua Gu,Vera Vollenweider et al.
Zhong Wei et al.
One Health is an integrative concept striving for healthy environments, animals, and humans. Microbes play a fundamental role for this concept as they are key drivers of ecosystem stability and host health. A central microbial feature acros...
Fungal cell walls: the rising importance of carbohydrate-active enzymes [0.03%]
真菌细胞壁：碳水化合物活性酶的重要性日益凸显
Roseline Assiah Yao,Jean-Guy Berrin,Lauren S McKee et al.
Roseline Assiah Yao et al.
As the interface between the fungal cell and its surroundings, the fungal cell wall (FCW) plays an essential physiological role in a myriad of biological processes. It provides support, protection, and enables material exchange with the env...
New genes on the block: additional open reading frames in the genomes of geminiviruses [0.03%]
基因新秀：弹状病毒基因组中的附加开放阅读框
Huang Tan,Fangfang Li,Xueping Zhou et al.
Huang Tan et al.
In their DNA genomes, the devastating plant-infecting geminiviruses contain partially overlapping genes which encode multifunctional proteins. For decades, geminiviral genomes were believed to contain four to eight open-reading frames (ORFs...
Frédérique Reverchon,Blondy Canto-Canché,Jorge Rocha et al.
Frédérique Reverchon et al.
The low science budget combined with the increase in the number of researchers creates challenging conditions for Mexican scientists to fund their research. Although these difficulties are shared by scientists from many other countries, doi...
Ruggero La Rosa,Søren Molin,Helle Krogh Johansen
Ruggero La Rosa
The persistence of Pseudomonas aeruginosa in chronic infections extends beyond the issue of antibiotic resistance. A critical, yet unresolved question is why antibiotics fail to eradicate all infecting bacteria, despite P. aeruginosa often ...
Abhirupa Ghosh,Charmie K Vang,Evan P Brenner et al.
Abhirupa Ghosh et al.
The global antimicrobial resistance (AMR) emergency is driven by complex and evolving molecular mechanisms. Cutting-edge machine learning methods and multiomics technologies can help to combat this crisis by predicting novel AMR biomarkers ...
Dimie Ogoina
Dimie Ogoina
Microbiology R&D is shaped by profit, interest, and noise, often to the detriment of public health in low-income countries. This article examines these inequities and proposes reforms to balance profit motives with public needs, align globa...