Features and algorithms: facilitating investigation of secreted effectors in Gram-negative bacteria [0.03%]
特征与算法——促进革兰氏阴性菌分泌效应蛋白的研究
Ziyi Zhao,Yixue Hu,Yueming Hu et al.
Ziyi Zhao et al.
Gram-negative bacteria deliver effector proteins through type III, IV, or VI secretion systems (T3SSs, T4SSs, and T6SSs) into host cells, causing infections and diseases. In general, effector proteins for each of these distinct secretion sy...
Junfei Ma,Shachinthaka D Dissanayaka Mudiyanselage,Jie Hao et al.
Junfei Ma et al.
Viroids are single-stranded circular noncoding RNAs that infect plants. According to the International Committee on Taxonomy of Viruses, there are 44 viroids known to date. Notably, more than 20 000 distinct viroid-like RNA sequences have r...
Piyoosh K Babele,Amit Srivastava,Jamey D Young
Piyoosh K Babele
Cyanobacteria generate energy from photosynthesis and produce various secondary metabolites with diverse commercial and pharmaceutical applications. Unique metabolic and regulatory pathways in cyanobacteria present new challenges for resear...
Avi I Flamholz,Akshit Goyal
Avi I Flamholz
Recent research has strengthened the notion that microbes allocate their biosynthetic capacity to maximize the growth rate, λ. Yet many microbes can grow substantially faster after laboratory evolution. Chure and Cremer advance a resource-...
Junhua Xie,Freddy Haesebrouck,Lien Van Hoecke et al.
Junhua Xie et al.
A growing body of research, especially in recent years, has shown that bacterial extracellular vesicles (bEVs) are one of the key underlying mechanisms behind the pathogenesis of various diseases like pulmonary fibrosis, sepsis, systemic bo...
Francisco Dini-Andreote,Gordon F Custer
Francisco Dini-Andreote
Fecal microbiota transplantation (FMT) is a procedure used to treat diseases related to microbiome imbalances. We discuss how ecological principles can inform the design of FMT clinical trials and contribute to data interpretation. This eff...
Stavros D Veresoglou,David Johnson
Stavros D Veresoglou
Symbioses involving microorganisms prevail in nature and are key to regulating numerous ecosystem processes and in driving evolution. A major concern in understanding the ecology of symbioses involving microorganisms arises in the effective...
Lu Luan,Francisco Dini-Andreote,Bo Sun et al.
Lu Luan et al.
Understanding the mechanisms structuring soil bacterial diversity has critical implications to advance the parametrization of species distribution models. This forum article discusses recent advances in the use of the metabolic theory of ec...
Kai Tang,Le Liu
Kai Tang
Bacteria are key players in the marine sulfur cycle, from the sunlit ocean surface to the dark abyssal depths. Here, we provide a brief overview of the interlinked metabolic processes of organosulfur compounds, an elusive sulfur cycling pro...
A framework for understanding and predicting orthohantavirus functional traits [0.03%]
正汉塔病毒功能特征的理解和预测框架
Nathaniel Mull,Stephanie N Seifert,Kristian M Forbes
Nathaniel Mull
Orthohantaviruses present a global public health threat; there are 58 distinct viruses currently recognized and case fatality of pathogenic orthohantaviruses ranges from