Mark D McDonald,Carlos Owusu-Ansah,Jared B Ellenbogen et al.
Mark D McDonald et al.
Life can be stressful. One way to deal with stress is to simply wait it out. Microbes do this by entering a state of reduced activity and increased resistance commonly called 'dormancy'. But what is dormancy? Different scientific discipline...
Jonathan P Zehr,Douglas G Capone
Jonathan P Zehr
Biological nitrogen (N2) fixation is critical in global biogeochemical cycles and in sustaining the productivity of the oceans. There remain many unanswered questions, unresolved hypotheses, and unchallenged paradigms. The fundamental balan...
Metagenomics and metabolomics approaches in the study of Candida albicans colonization of host niches: a framework for finding microbiome-based antifungal strategies [0.03%]
基因组学和代谢组学在研究白色念珠菌定植宿主生态位中的作用:寻找基于微生物群的抗真菌策略框架
Margot Delavy,Natacha Sertour,Christophe dEnfert et al.
Margot Delavy et al.
In silico and experimental approaches have allowed an ever-growing understanding of the interactions within the microbiota. For instance, recently acquired data have increased knowledge of the mechanisms that support, in the gut and vaginal...
Why do hosts malfunction without microbes? Missing benefits versus evolutionary addiction [0.03%]
无微生物情况下宿主发生故障的原因:利益缺失还是进化上瘾?
Tobin J Hammer
Tobin J Hammer
Microbes are widely recognized to be vital to host health. This new consensus rests, in part, on experiments showing how hosts malfunction when microbes are removed. More and more microbial dependencies are being discovered, even in fundame...
Kara R Eichelberger,Saikat Paul,Brian M Peters et al.
Kara R Eichelberger et al.
While the fungus Candida albicans is a common colonizer of healthy humans, it is also responsible for mucosal infections and severe invasive disease. Understanding the mechanisms that allow C. albicans to exist as both a benign commensal an...
Burkholderia pseudomallei [0.03%]
巴氏疏假单胞菌
Erica D Phillips,Erin C Garcia
Erica D Phillips
Burkholderia pseudomallei is a Gram negative, facultative intracellular bacterium that resides in the rhizosphere of tropical soils. B. pseudomallei causes melioidosis, which is transmitted by cutaneous entry, ingestion, or inhalation of co...
The role of microbial biofilms in range shifts of marine habitat-forming organisms [0.03%]
微生物生物膜在海洋建底栖生物群落分布变化中的作用
Christopher Cooney,Brigitte Sommer,Ezequiel M Marzinelli et al.
Christopher Cooney et al.
Marine species, such as corals and kelp, are responding to climate change by altering their distributions. Microbial biofilms underpin key processes that affect the establishment, maintenance, and function of these dominant habitat-formers....
Programming therapeutic probiotics by self-tunable sense-and-respond genetic circuits [0.03%]
利用可自调的感应与反应基因线路编程治疗用益生菌
Yuxin Liu,Zhengming Zhu,Ling Jiang
Yuxin Liu
Probiotics can be programmed to sense and respond to intracellular disease signals to deliver the desired therapeutic effectors. The sense-and-respond genetic circuits, especially self-tunable ones, hold promise in improving the precision, ...
Exploiting root exudates to manage soil-borne disease complexes in a changing climate [0.03%]
利用根系分泌物在气候变化下管理土传病害复合体
Jay Ram Lamichhane,Martin J Barbetti,Martin I Chilvers et al.
Jay Ram Lamichhane et al.
Ongoing climate change will both profoundly impact land-use (e.g., changes in crop species or cultivar and cropping practices) and abiotic factors (e.g., moisture and temperature), which will in turn alter plant-microorganism interactions i...
Beyond butyrate: microbial fiber metabolism supporting colonic epithelial homeostasis [0.03%]
超越丁酸:微生物纤维代谢支持结肠上皮稳态
Raphael R Fagundes,Saskia C Belt,Barbara M Bakker et al.
Raphael R Fagundes et al.
Human gut bacteria produce metabolites that support energy and carbon metabolism of colonic epithelial cells. While butyrate is commonly considered the primary fuel, it alone cannot meet all the carbon requirements for cellular synthetic fu...