Yukun Liu,Shuguo Hou
Yukun Liu
Bacterial pathogens deliver effectors into host cells mostly to manipulate signaling and metabolic molecules, thereby subverting host immunity. A recent study by Nomura et al. demonstrates that certain effectors create membrane channels in ...
Xiaofei Cheng,Xiaoyun Wu,Rongxiang Fang
Xiaofei Cheng
It is widely accepted that the minus strands of positive single-strand RNA (+ssRNA) viruses function as replication templates only. Gong et al. revealed that the minus strand of two unrelated +ssRNA viruses encodes proteins. This textbook-c...
Abishek Balakumar,Douglas Bernstein,Shankar Thangamani
Abishek Balakumar
Candida auris is an emerging human fungal pathogen that can rapidly spread and cause outbreaks of invasive infections. Santana et al. discovered that a novel surface colonization factor (SCF1), and a conserved adhesin, Iff4109, mediates C. ...
Lu Zhang,Lingyun Guo,Zhongli Cui et al.
Lu Zhang et al.
Predatory bacteria have been increasingly known for their ubiquity in environments and great functional potentials in controlling unwanted microorganisms. Fundamental understanding of the predation mechanisms, population dynamics, and inter...
Traits-based approach: leveraging genome size in plant-microbe interactions [0.03%]
基于性状的方法：在植物-微生物互作中利用基因组大小
Haiyang Zhang,Hongwei Liu,Xingguo Han
Haiyang Zhang
Trait-based approaches have gained growing interest in studying plant-microbe interactions. However, current traits normally considered (e.g., morphological, physiological, or chemical traits) are biased towards those showing large intraspe...
Targeting wheat fusarium head blight with mycovirus-mediated VIGS [0.03%]
利用担子病毒介导的VIGS技术靶向小麦赤霉病的研究进展
Junqi Zhang,Xuetao Shi,Wende Liu
Junqi Zhang
Fusarium head blight (FHB) caused by Fusarium graminearum occurs in wheat (Triticum aestivum) and threatens food production worldwide. Wheat lacks broad, durable FHB resistance. However, Zhang et al. developed a mycovirus-based virus-induce...
Dmytro Kompaniiets,Dong Wang,Yang Yang et al.
Dmytro Kompaniiets et al.
Transcription activation is an important checkpoint of regulation of gene expression which occurs in response to different intracellular and extracellular signals. The key elements in this signal transduction process are transcription activ...
Rebekah A Jones,Ann E Jerse,Christoph M Tang
Rebekah A Jones
Neisseria gonorrhoeae is a human-specific pathogen responsible for the sexually transmitted infection, gonorrhoea. N. gonorrhoeae promotes its survival by manipulating both innate and adaptive immune responses. The most abundant gonococcal ...
Cellular rejuvenation to combat HIV-1-related neurocognitive impairment [0.03%]
细胞复苏对抗与HIV-1相关的神经认知障碍
Philipp N Ostermann,Teresa H Evering
Philipp N Ostermann
HIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies...
Ákos T Kovács
Ákos T Kovács
Plant-microbiome functioning depends on intricate signaling pathways including plant-derived excretions that induce microbial gene expression. Marc Ongena and his team (Boubsi et al.) dissect how the pectin backbone homogalacturonan promote...