Boyang Song,Wencheng Shi,Dingjiacheng Jia
Boyang Song
Beyond the commonly considered factor of diet, small-molecule drugs have been identified as effectors of microbiota composition. Recently, two studies (Grießhammer et al. and Kumar et al.) reported that non-antibiotics, like antibiotics, c...
RNA modifications in plant pathogenic fungi: from epitranscriptomics to antifungal strategies [0.03%]
植物病原真菌中的RNA修饰：从表观转录组学到抗真菌策略
Hong Hu,Yinan Li,Ziwei Lv et al.
Hong Hu et al.
Traditional antifungal agents such as polyene, azole, and echinocandin antifungals are restricted because of antifungal resistance and off-target effects. Given these limitations, there is an urgent need to explore novel antifungal strategi...
Tobias Baril,Daniel Croll
Tobias Baril
Recent research on human and crop fungal pathogens has highlighted a set of unexpected and seemingly unrelated mechanisms fuelling adaptation to drugs and the host immune system. These mechanisms include the loss of RNA interference (RNAi) ...
Luna Eresta Jaya,Ilana L Brito
Luna Eresta Jaya
Antibiotic use can significantly alter the gut microbiome, impacting health outcomes across diverse regions. Geographic differences in baseline microbiome composition, antibiotic-resistance gene (ARG) carriage, antibiotic usage patterns, an...
Geographic diversity in inflammatory bowel disease genetics and microbiome [0.03%]
炎症性肠病遗传学及微生物群的地域差异性
Fangjia Hao,Wenyi Zhu,Jiaying Zheng et al.
Fangjia Hao et al.
Inflammatory bowel disease (IBD) is characterized by dysregulation of the immune response to gut microbiota, a phenomenon that intertwines with environmental influences and manifests as intestinal inflammation in genetically susceptible hos...
Jinal N Bhiman,Jennifer Serwanga,Chinedu A Ugwu et al.
Jinal N Bhiman et al.
The Global Immunology and Immune Sequencing for Epidemic Response (GIISER) network, established in 2021, exemplifies the power of South-South collaboration in pandemic preparedness and response. Emerging from the COVID-19 crisis, GIISER int...
Francisco Rodriguez-Valera,Carmen Molina-Pardines
Francisco Rodriguez-Valera
The prokaryotic pangenome, the full complement of genes within a species, is strikingly large. To understand how ecological forces shape this diversity, it is useful to examine the variable gene pool within a single population, defined as c...
Guofan Zhu,Francisco Dini-Andreote,Shungui Zhou et al.
Guofan Zhu et al.
Soils are highly heterogeneous ecosystems hosting multiple organisms engaged in trophic interactions. We introduce the economic spectrum of soil food webs - a trait-based framework spanning a fast-to-slow continuum - that offers a more inte...
Decoding mosquito-virus interactions: from classical genetics to multi-omics [0.03%]
蚊虫病毒互作的解析——从经典遗传学到多组学研究
Elodie Couderc,Louis Lambrechts,Sarah H Merkling
Elodie Couderc
Arbovirus transmission by mosquitoes remains a major global health concern. A clearer understanding of the molecular mechanisms enabling mosquitoes to acquire and transmit these pathogens (i.e., their vector competence) is crucial for devel...
Tatsuya Nobori
Tatsuya Nobori