Rethinking microbially driven methane formation in mangrove wetlands [0.03%]
重新思考红树林湿地中由微生物驱动的甲烷形成过程
Ruiwen Hu,Zhili He,Cheng Wang
Ruiwen Hu
Mangrove wetlands contribute to climate change mitigation through efficient carbon burial, yet microbial methanogenesis offsets these climate benefits. We review the diversity of methanogenic microorganisms in mangrove sediments, present th...
KAP1/TRIM28 - antiviral and proviral protagonist of herpesvirus biology [0.03%]
KAP1/TRIM28-疱疹病毒生物学中的抗病毒和利病毒的主角
Sumita Bhaduri-McIntosh,Beth A Rousseau
Sumita Bhaduri-McIntosh
Dysregulation of the constitutive heterochromatin machinery (HCM) that silences pericentromeric regions and endogenous retroviral elements in the human genome has consequences for aging and cancer. By recruiting epigenetic regulators, Krüp...
Biao Hu,Jianping Chen,Zongtao Sun
Biao Hu
The transmission of flaviviruses, such as dengue virus (DENV) and Zika virus (ZIKV), poses a significant threat to global public health. Zhang et al. recently showed that Rosenbergiella sp. YN46 (Rosenbergiella_YN46), a bacterium from the m...
The growing repertoire of phage anti-defence systems [0.03%]
噬菌体反防御系统的日益扩增(repertoire复数形式repertoires)
Khalimat Murtazalieva,Andre Mu,Aleksandra Petrovskaya et al.
Khalimat Murtazalieva et al.
The biological interplay between phages and bacteria has driven the evolution of phage anti-defence systems (ADSs), which evade bacterial defence mechanisms. These ADSs bind and inhibit host defence proteins, add covalent modifications and ...
Unraveling host regulation of gut microbiota through the epigenome-microbiome axis [0.03%]
表观基因组-微生物组轴与肠道菌群稳态及疾病的关系研究进展
Michael L Pepke,Søren B Hansen,Morten T Limborg
Michael L Pepke
Recent studies of dynamic interactions between epigenetic modifications of a host organism and the composition or activity of its associated gut microbiota suggest an opportunity for the host to shape its microbiome through epigenetic alter...
Inside the microbial black box: a redox-centric framework for deciphering microbial metabolism [0.03%]
透视微生物的“黑箱”：一个以氧化还原反应为中心的框架来解析微生物代谢
John A Bouranis,Malak M Tfaily
John A Bouranis
Microbial metabolism influences the global climate and human health and is governed by the balance between NADH and NAD+ through redox reactions. Historically, oxidative (i.e., catabolism) and reductive (i.e., fermentation) pathways have be...
Broadening the targetable space: engineering and discovery of PAM-flexible Cas proteins [0.03%]
扩展靶向空间：工程改造和发现PAM灵活的Cas蛋白
Zhenkun Cai,Weiyu Xie,Zehua Bao
Zhenkun Cai
The application of CRISPR-Cas systems has been hindered by their requirement for long protospacer-adjacent motifs (PAMs). Recent engineering and discovery of PAM-flexible Cas proteins have substantially broadened the targetable DNA sequence...
Gene transfer agents: structural and functional properties of domesticated viruses [0.03%]
基因转移代理：驯化病毒的结构和功能属性
Matthew W Craske,Jason S Wilson,Paul C M Fogg
Matthew W Craske
Horizontal exchange of DNA between bacteria and archaea is prevalent and has major potential implications for genome evolution, plasticity, and population fitness. Several transfer mechanisms have been identified, including gene transfer ag...
Kirsty J Marsh,Stuart Bearhop,Xavier A Harrison
Kirsty J Marsh
Ignoring the dynamic nature of microbial communities risks underestimating the power of microbes to impact the health of their hosts. Microbiomes are thought to be important for host fitness, yet the coarse temporal scale and population-lev...
Influence of antimicrobial peptides on the bacterial membrane curvature and vice versa [0.03%]
抗菌肽对细菌膜曲率的影响以及反之
Marlon H Cardoso,Cesar de la Fuente-Nunez,Nuno C Santos et al.
Marlon H Cardoso et al.
Many factors contribute to bacterial membrane stabilization, including steric effects between lipids, membrane spontaneous curvature, and the difference in the number of neighboring molecules. This forum provides an overview of the physicoc...