Mahwash Jamy,Pierre Ramond,David Bass et al.
Mahwash Jamy et al.
Protists comprise the vast majority of eukaryotic genetic and functional diversity. While they have traditionally been difficult to study due to their small size and varied phenotypes, environmental sequencing studies have revealed the stun...
Strengthening cGMP capabilities for microbiology and immunology clinical research in South America [0.03%]
南美微生物学和免疫学生物制剂现行良好制造规范能力的提升
Susan M Bueno,Pablo A González,Alexis M Kalergis
Susan M Bueno
In South America, few countries can produce vaccines and biologics for clinical research under current good manufacturing practices (cGMP), which is a significant barrier to translating applied microbiology and immunology research into clin...
Jingdi Li
Jingdi Li
Katherine M Klier,Karthik Anantharaman
Katherine M Klier
From the human gut to the deep ocean, diverse microbial communities underpin essential ecosystem processes. Limited understanding of the dynamics and interactions that shape these communities, however, constrains efforts to culture, investi...
Bacillus velezensis [0.03%]
解糖孤菌
Marta Torres,Inmaculada Sampedro,Inmaculada Llamas et al.
Marta Torres et al.
Anouk Gremion,Madhav P Thakur
Anouk Gremion
Microbial-assisted restoration (MaR) is gaining traction, yet its outcomes under recurring and extreme drought remain uncertain. We propose that ecological debt - functional erosion from trade-offs between stress tolerance and performance -...
Jasmin Hatami,Anja C M de Bruin,Zoltán Bánki et al.
Jasmin Hatami et al.
Alphaviruses are mosquito-borne pathogens causing rheumatological disease and encephalomyelitis. Their spread, enhanced by climate change, presents a growing global health threat. To date, no specific treatments and, except for chikungunya ...
Jiaqi Fu,Zhao-Qing Luo,Jiazhang Qiu
Jiaqi Fu
Protein post-translational modifications (PTMs) serve as essential molecular switches that dynamically modulate cell signaling in response to developmental or external cues. Effective interference with host signaling is critical for success...
Pathobiont immune tuning: the untold consequences of Staphylococcus aureus exposure on host immunity [0.03%]
病原菌对免疫的调节作用——金黄色葡萄球菌接触对宿主免疫的未被充分认知的影响
Seán C Cahill,Elisabetta Soldaini,Rachel M McLoughlin
Seán C Cahill
Staphylococcus aureus is a formidable pathogen and major challenge to human health. However, the bacterium is dichotomous and also acts as an asymptomatic coloniser. Given its ubiquity, every individual has been exposed to the bacterium, wh...
Xia Shu,Yunpeng Liu
Xia Shu
Stable SynCom design remains challenging due to unpredictable microbial interactions. Contrary to the traditional focus on broad-spectrum strains, Wang et al. revealed that narrow-spectrum bacteria act as metabolic hubs, promoting cooperati...