Association between C-reactive protein to lymphocyte ratio and depression: A population-based study [0.03%]
C-反应蛋白与淋巴细胞比值和抑郁症的关联：一项基于人群的研究
Ziyang Zheng,Jiaqi Wu,Qinyang Shi
Ziyang Zheng
Background: Emerging biomarkers like the C-reactive protein to lymphocyte ratio (CLR) have been associated with various diseases and may be useful for evaluating depression risk. This study investigates the association be...
Precision pharmacology of CNS GPCRs: From biased signaling to translational therapeutics [0.03%]
偏向信号传导在中枢神经系统GPCRs精确诊疗中的转化作用
Teja Reddy Gujjula,Ekambaram Bhavya,Reena Gupta et al.
Teja Reddy Gujjula et al.
G protein-coupled receptors (GPCRs) represent one of the most extensively targeted receptor families in central nervous system (CNS) pharmacology. Recent advances in GPCR biology have transformed traditional paradigms by introducing concept...
Integrating multi-omics analysis to identify potential biomarkers and regulatory networks of ischemic stroke [0.03%]
整合多组学分析以识别缺血性卒中的潜在生物标志物和调控网络
Ziyi Hou,Yuanyuan Li,Liyuan Pu et al.
Ziyi Hou et al.
Ischemic stroke (IS) is a leading cause of death and long-term disability worldwide, with a complex and multifactorial pathophysiology that is still incompletely understood. This study performed untargeted metabolomics and Olink proteomics ...
Age of onset of bipolar disorder: Association with lifetime psychiatric disorders and health-related quality of life [0.03%]
双相障碍的发病年龄与其终生精神病患病情况及与健康相关的生活质量的关系
Camille Jamet,Caroline Dubertret,Nicolas Mazer et al.
Camille Jamet et al.
Introduction: Bipolar Disorder (BD) is common in children, adolescents and adults. Early-onset BD has been associated with a more severe clinical course and greater long-term impairment. However, the specific associations...
Advances in schizophrenia research and treatment: exploring neurotransmitter imbalances, genetics, and innovative therapies [0.03%]
精神分裂症研究与治疗新进展：探索神经递质失衡、遗传学及创新疗法
Karolína Škutová,Zdeněk Fišar,Jana Hroudová
Karolína Škutová
Schizophrenia is a severe mental disorder arising from genetic vulnerability, impaired neurodevelopment, neurobiological dysregulation, and environmental factors. Its pathophysiology involves disturbances in dopamine, glutamate, and seroton...
Andrea Herrera-Solís,Alejandro Hernández-Lira,Alejandra E Ruiz-Contreras et al.
Andrea Herrera-Solís et al.
Anxiety is one of the most prevalent psychiatric disorders. Although people may feel anxiety when they suffer from a pathological condition, it is also a disorder in itself. However, under normal conditions, anxiety facilitates adaptation. ...
The intersection of immunity and mental health: Immunotherapy's role in modulating depression and neuropsychiatric disorders [0.03%]
免疫和精神健康之间的交叉点：免疫疗法在调节抑郁和其他神经精神疾病中的作用
Tanvi Premchandani,Mohammad Qutub,Tanu Hatel et al.
Tanvi Premchandani et al.
Depression is increasingly recognized as a heterogeneous disorder, with a substantial subset of cases driven by immune dysregulation. This review synthesizes current evidence on the bidirectional relationship between the immune system and m...
The role of alcohol metabolizing gene in patients with alcohol use disorder and heroin use disorder in the Taiwan Han Chinese population [0.03%]
酒精代谢基因在台湾汉族人群中酒精使用障碍和海洛因使用障碍患者中的作用研究
Yao-Cheng Wu,Chun-Yen Chen,Shin-Chang Kuo et al.
Yao-Cheng Wu et al.
Introduction: Alcohol and heroin are classified as central nervous depressants. Their addiction has a strong genetic component, although the specific genetic variations involved are not fully understood. This study invest...
TMS-biomarkers discovery in children and adolescents with neurological disorders: A systematic review and meta-analysis [0.03%]
儿童和青少年神经障碍相关生物标志物发现的系统综述和荟萃分析
Wen Yurong,Cheng Si,Hasi Bageng et al.
Wen Yurong et al.
This systematic review and meta-analysis examined the application of transcranial magnetic stimulation (TMS) electrophysiological biomarkers in children and adolescents, focusing on their role in assessing neurological disorders. We synthes...
Metabotropic glutamate receptors in the testis: An integrative bioinformatic review of neuroendocrine, reproductive, and Neuropsychopharmacological aspects [0.03%]
睾丸代谢型谷氨酸受体：神经内分泌、生殖和神经药理学方面的综合生物信息学综述
Tommaso Barlattani,Matteo Caridi,Valeria Pellicelli et al.
Tommaso Barlattani et al.
Metabotropic glutamate receptors (mGluRs) are best known for modulating synaptic transmission, yet accumulating evidence shows that they are also widely expressed in peripheral tissues, including the testis. Methodologically, this work inte...