Fluoxetine-associated adverse event signals with a focus on seizure: A study based on the FAERS database, network pharmacology, and molecular docking [0.03%]
基于FAERS数据库、网络药理学及分子对接的氟西丁不良事件信号研究（重点为惊厥）
Cui Cheng,Jun Li,Huihui Zhang et al.
Cui Cheng et al.
Objective: To evaluate fluoxetine-associated adverse event reporting signals in the FDA Adverse Event Reporting System (FAERS), focusing on seizure, and to explore potential biological plausibility using network pharmacol...
Source-level EEG dysconnectivity in drug-naïve patients with major depressive disorder: Bridging neural oscillations with potential neuroelectrophysiological markers [0.03%]
无药物治疗的抑郁症患者源级EEG功能连接异常：神经振荡与潜在的神经电生理标志物之间的关系
Ciqing Bao,Haowen Zou,Yi Xia et al.
Ciqing Bao et al.
Background: Electroencephalogram (EEG)-based source localization offers a new perspective for investigating the neurophysiological origins of functional connectivity (FC) disruptions in major depressive disorder (MDD). Th...
Deciphering the molecular mechanisms of fluoxetine-induced sexual dysfunction: Evidence from pharmacovigilance, network toxicology, and molecular docking [0.03%]
解读氟西丁引起的性功能障碍的分子机制：来自药物警戒、网络毒理学和分子对接的证据
Jun Li,Xing Wang,Yunfeng Zhang et al.
Jun Li et al.
Objective: To evaluate the association between fluoxetine and sexual dysfunction using real-world pharmacovigilance data and to explore its potential molecular mechanisms through network toxicology and molecular docking. ...
Chronic cocaine exposure modulates decision-making in mice in a sex-dependent manner [0.03%]
慢性可卡因暴露以性别依赖的方式调节小鼠的决策行为
Abhishek Shankar Balakrishnan,Cesar Ramon Romero-Leguizamón,Zuzanna Mincikiewicz et al.
Abhishek Shankar Balakrishnan et al.
Women progress from initial cocaine use to cocaine use disorder more rapidly than men, possibly reflecting cocaine-induced impairments in decision-making. Human gambling task (GT) studies investigating the effects of cocaine use have shown ...
FAM26F is a novel regulator of depression-related behaviors by modulating hippocampal glutamatergic neuron activity [0.03%]
FAM26F通过调节海马区谷氨酸能神经元活性调控与抑郁相关行为的新机制研究
Yifan Cao,Lin Du,Shasha Zhang et al.
Yifan Cao et al.
Major depressive disorder is a leading cause of disability that significantly exacerbates the disease burden worldwide. FAM26F is a calcium homeostasis regulatory protein, and no studies have reported on its expression and function in brain...
State anxiety may mediate the association between striato-cortical circuitry and anxiety symptom severity in generalized anxiety disorder: A resting-state fMRI study and support vector machine analysis [0.03%]
状态焦虑可能介导了壳核-皮层环路与广泛性焦虑障碍症状严重程度之间的关系：一项静息态功能磁共振成像研究及支持向量机分析
Guanmao Chen,Feng Chen,Ying Zhang et al.
Guanmao Chen et al.
Background: Patients with generalized anxiety disorder (GAD) show structural and functional striatal abnormalities. While state and trait anxiety are known to modulate neural circuits influencing anxiety progression, the ...
Psychometric validation of the French version of the five-dimensional altered states of consciousness questionnaire (5D-ASC) and associated 11 OAV subscales [0.03%]
五维意识状态问卷（5D-ASC）和相关11个OAV子量表的法文版的心理测量验证研究
Ewen Kervadec,Pauline Mathieu,Baptiste Fauvel et al.
Ewen Kervadec et al.
Introduction: The renewal of psychedelic medicine has garnered significant scientific interest, with large efforts dedicated to the understanding of the complex subjective experiences induced by these substances. The Alte...
Subregion-specific insular dysconnectivity in internet gaming disorder: From macroscale network abnormalities to transcriptomic and cellular substrates [0.03%]
互联网游戏障碍的岛叶亚区连接异常：从宏观网络异常到转录组和细胞基底
Qinxuan Li,Haichao Zhao,Ofir Turel et al.
Qinxuan Li et al.
The insular cortex is a pivotal hub for interoception and salience processing, yet subregion-specific circuit abnormalities in Internet Gaming Disorder (IGD) and their molecular correlates remain unclear. Using resting-state fMRI data from ...
Synergistic-redundant dysfunction in autism spectrum disorder: Heterogeneity and molecular mechanisms [0.03%]
自闭症谱系障碍中的协同冗余功能障碍：异质性和分子机制
Wei Li,Shuhua He,Jin Chen et al.
Wei Li et al.
Delineating the systematic functional integration and regional functional robustness in shared and individual-specific subspaces is critical to elucidating the neural basis underlying social and cognitive deficits in autism spectrum disorde...
Association of Esketamine use with mortality and clinical outcomes in patients with cancer-related depression: A target trial emulation [0.03%]
氯胺酮衍生物艾司氯胺酮在癌症相关抑郁患者中使用与死亡率和临床结局的关系：目标试验模拟研究
Jen-Ping Chen,Chih-Wei Hsu,Yi-Ya Fang et al.
Jen-Ping Chen et al.
Although esketamine shows efficacy for treatment-resistant depression, its potential effectiveness in cancer-related depression (CRD) has not been well-established. We therefore evaluated the real-world effectiveness and safety of esketamin...