Efficacy of Bone-Modifying Agents in Preventing Vertebral Complications of Multiple Myeloma: A Systematic Review and Meta-Analysis [0.03%]
骨改良药物预防多发性骨髓瘤椎体并发症疗效的系统评价和meta分析
Zsombor T Gal,Ethan A Wetzel,Brian V Nahed et al.
Zsombor T Gal et al.
Background context: Bone disease in patients with multiple myeloma (MM) is associated with vertebral complications, which include vertebral fractures and spinal cord compression (SCC). Bone-modifying agents (BMAs), namely...
Electronic and Conventional Cigarette Use and Risk of Spinal Disc Disorders: A Nationwide Cohort Study [0.03%]
电子烟和传统香烟的使用与脊椎间盘疾病的发病风险之间的关系:全国队列研究
Jae Won Shin,Ji-Won Kwon,Sung Youn Chun et al.
Jae Won Shin et al.
Background context: Liquid electronic cigarettes (LECs), heat-not-burn electronic cigarettes (HECs), and combustible cigarettes (CCs) pose varying disc disease risks. ...
THE EFFECTS OF METABOLIC AND BARIATRIC SURGERY ON SPINAL ALIGNMENT, RADIOLOGICAL, AND CLINICAL OUTCOMES IN MORBIDLY OBESE PATIENTS WITH LBP: A SYSTEMATIC REVIEW AND META-ANALYSIS [0.03%]
代谢及减肥手术对重度肥胖伴腰痛患者的脊柱排列、影像学和临床结果的影响:系统回顾和荟萃分析
Khaled Aboushaala,Othman Ibrahim,Namrah Ahmed et al.
Khaled Aboushaala et al.
Background: Metabolic and bariatric surgery (MBS), employing mechanisms like malabsorption, volume restriction, and metabolic changes via the gastrointestinal tract, is the most effective long-term treatment for obesity a...
The Effect of Paraspinal Sarcopenia on Postoperative Sagittal Balance: A Multivariate Analysis Following Multilevel Lumbar Fusion Surgery [0.03%]
多节段腰椎融合术后旁脊髓肌减少对术后轴向平衡影响的多元分析
Tianci Fang,Zhifang Xue,Junxin Zhang et al.
Tianci Fang et al.
Background context: Paraspinal muscles play a crucial role in maintaining lumbar spine stability and sagittal alignment. However, the impact of sarcopenia on long-term sagittal balance and clinical outcomes following mult...
Effect of Casein Kinase 1 epsilon on promoting cartilage degeneration in lumbar facet joint osteoarthritis [0.03%]
酪蛋白激酶1epsilon促进腰椎小关节骨关节炎软骨退变的作用及机制研究
Lixian Tan,Tianwei He,Runmin Tang et al.
Lixian Tan et al.
Background context: Lumbar facet joint osteoarthritis (FJOA) is a major cause of low back pain, yet its molecular mechanisms remain poorly understood. Casein Kinase 1 epsilon (CK1ε) has been implicated in osteoarthritis,...
Anterior Cervical Discectomy and Fusion Provides Better Outcome Compared to Posterior Cervical Foraminotomy When Foramen is Vertically Narrow [0.03%]
与后路颈椎间孔切骨术相比,前路颈椎间盘切除融合术可更有效治疗垂直向狭窄的颈椎间盘突出症
Sehan Park,Dong-Ho Lee,Chang Ju Hwang et al.
Sehan Park et al.
Background context: Posterior cervical foraminotomy (PCF) cannot widen the neural foramen vertically, whereas anterior cervical discectomy and fusion (ACDF) could increase foraminal height (FH) by distracting the disc spa...
Development of an internationally agreed national minimum dataset for low back pain: a modified Delphi study [0.03%]
建立国际认可的国家级最低腰痛数据集:一项改良德尔菲研究
Bayden J McKenzie,Giovanni E Ferreira,Romi Haas et al.
Bayden J McKenzie et al.
Background: Low back pain is the leading cause of disability worldwide and the burden is expected to rise due to increases in ageing and population growth. The 2018 Lancet Low Back Pain Series proposed urgent actions to r...
Trends in utilization of lumbar facet injection and radiofrequency ablation through Veterans Health Administration: 2007-2020 [0.03%]
2007年至2020年退伍军人医疗保健提供者使用腰椎小关节阻滞和射频消融治疗慢性背痛的趋势:回顾性队列研究
W Evan Rivers,Eva Thomas,Jessica Chen et al.
W Evan Rivers et al.
Background context: Previous studies have described utilization trends for lumbar facet pain procedures (LFP) over the past 2 decades in Medicare and commercially-insured populations. No studies have examined LFP utilizat...
Parisa Akhlaghi,Remco Doodkorte,Peter Lafranca et al.
Parisa Akhlaghi et al.
Background context: Degeneration of the intervertebral discs (IVDs) causes significant biomechanical changes and structural defects, often leading to pain or disability. These defects impair both the biomechanics and phys...
The STAT3/S100A6/P53/SLC7A11 axis mediates intervertebral disc degeneration by regulating ferroptosis in nucleus pulposus cells and the metabolism of the extracellular matrix [0.03%]
STAT3/S100A6/P53/SLC7A11轴通过调节髓核细胞铁死亡及细胞外基质代谢介导椎间盘退变
Fengguang Yang,Xuening Liu,Yizhi Zhang et al.
Fengguang Yang et al.
Background context: Intervertebral disc degeneration (IVDD) may be age-related, and is often seen in evaluating patients with low back pain (LBP). However, the specific molecular mechanisms underlying IVDD remain incomple...