David Montaigne,Anju Duva Pentiah
David Montaigne
Mitochondrial dysfunction has been shown to be involved in the pathophysiology of arrhythmia, not only in inherited cardiomyopathy due to specific mutations in the mitochondrial DNA but also in acquired cardiomyopathy such as ischemic or di...
Deepak Acharya,Harish Doppalapudi,José A Tallaj
Deepak Acharya
Fabry disease is an X-linked multisystem disorder caused by deficiency of the α-galactosidase A enzyme. Cardiovascular manifestations include hypertension, coronary disease, arrhythmias, valvular abnormalities, heart failure, and sudden de...
A John Baksi,G Sunthar Kanaganayagam,Sanjay K Prasad
A John Baksi
Acute viral myocarditis and acute pericarditis are self-limiting conditions that run a benign course and that may not involve symptoms that lead to medical assessment. However, ventricular arrhythmia is frequent in viral myocarditis. Myocar...
Chris Healy,Juan F Viles-Gonzalez,Luis C Sáenz et al.
Chris Healy et al.
Chagas disease, a chronic parasitosis caused by the protozoa Trypanosoma cruzi, is an increasing worldwide problem because of the number of cases in endemic areas and the migration of infected individuals to more developed regions. Chagas d...
Matthew M Zipse,William H Sauer
Matthew M Zipse
Myocardial involvement in patients with sarcoidosis can be difficult to diagnose, and requires a high index of suspicion and low threshold for screening. The presentation of cardiac sarcoidosis is variable, and can range from asymptomatic e...
Saurabh Kumar,William G Stevenson,Roy M John
Saurabh Kumar
Patients with dilated cardiomyopathies (DCM) face a significant burden of arrhythmias, including conduction defects such as atrioventricular block and interventricular delay in the form of left bundle branch block, resulting in altered elec...
Mohammad Shenasa,Hossein Shenasa,Nabil El-Sherif
Mohammad Shenasa
Left ventricular hypertrophy (LVH) poses an independent risk of increased morbidity and mortality, including atrial arrhythmias, ventricular arrhythmias, and sudden cardiac death. The most common causes of LVH are hypertension and valvular ...
Abhishek C Sawant,Hugh Calkins
Abhishek C Sawant
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associated with life-threatening arrhythmias and increased risk of sudden cardiac death. In addition to mutations in desmosomal genes, environmental f...
The role of cardiovascular magnetic resonance in sudden death risk stratification in hypertrophic cardiomyopathy [0.03%]
心脏磁共振在肥厚型心肌病猝死风险分层中的作用
Martin S Maron
Martin S Maron
Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden death in young patients, but current risk stratification strategies do not identify all patients at risk. Contrast-enhanced cardiovascular magnetic resonance (CMR) with la...
Kartik R Kumar,Swati N Mandleywala,Mark S Link
Kartik R Kumar
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants th...