Known Unknowns in the Contemporary Management of High-Risk Pulmonary Embolism: What Do the Guidelines Tell Us [0.03%]
高危肺栓塞现代治疗的已知和未知问题——指南怎么说？
Chaitra Janga,Anand Reddy Maligireddy,Vikas Aggarwal et al.
Chaitra Janga et al.
Pulmonary embolism (PE) is a life-threatening condition with increasing hospital admissions. Prompt identification and treatment of PE patients with hemodynamic collapse are essential. Conflicting recommendations and weak evidence hinder ef...
Amine Nasri,Riyaz Bashir,Vladimir Lakhter
Amine Nasri
Since the publication of the first case series reporting the outcomes of patients with chronic thromboembolic pulmonary hypertension who underwent treatment with balloon pulmonary angioplasty more than 30 years ago, significant improvements...
Novel Risk Stratification and Hemodynamic Profiling in Acute Pulmonary Embolism: A Proposed Classification Inspired by Society for Cardiovascular Angiography and Intervention Shock Staging [0.03%]
急性肺栓塞新型风险分层及血流动力学分类的构建——基于SCAI休克分型体系的初步探讨
Sonali Arora,Saraschandra Vallabhajosyula,Vikas Aggarwal et al.
Sonali Arora et al.
Treatment options for patients with acute pulmonary embolism (PE) and right ventricular shock (RVS) have grown exponentially. Therapy options include anticoagulation, systemic thrombolysis, catheter-based thrombolysis/ thrombectomy, and may...
Madathilparambil V Suresh,Vikas Aggarwal,Krishnan Raghavendran
Madathilparambil V Suresh
Hypoxia-inducible factors (HIFs) are a family of nuclear transcription factors that serve as the master regulator of the adaptive response to hypoxia. In the lung, HIFs orchestrate multiple inflammatory pathways and signaling. They have bee...
Muhammad Adil Sheikh,Gabriella VanAken,Syed Nabeel Hyder et al.
Muhammad Adil Sheikh et al.
Many patients discharged after an acute pulmonary embolism (PE) admission have inconsistent outpatient follow-up and insufficient workup for chronic complications of PE. A structured outpatient care program is lacking for the different phen...
Evolving Role and Clinical Evidence in the Global Practice of Balloon Pulmonary Angioplasty [0.03%]
球囊肺动脉成形术的全球实践及其临床证据和角色变迁
Nishant Jain,Sidney Perkins,Anand Reddy Maligireddy et al.
Nishant Jain et al.
Balloon pulmonary angioplasty (BPA) was first described in 2001 and now has evolved into a class I indication for inoperable or residual chronic thromboembolic pulmonary hypertension. This review article aims to describe evidence from studi...
Harshvardhan Zala,Huseyin Emre Arman,Saurav Chatterjee et al.
Harshvardhan Zala et al.
Venous thromboembolism (VTE) usually develops in the deep veins of the extremities. Pulmonary embolism (PE) is a type of VTE that is most commonly (∼90%) caused by a thrombus that originates from the deep veins of the lower extremities. PE...
Scott H Visovatti
Scott H Visovatti
Center of excellence (COE) designations are generally used to identify programs with expertise in a specific area of medicine. Meeting criteria for a COE may result in advantages including improved clinical outcomes, marketing advantages, a...
The Evolution of Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension [0.03%]
肺动脉去神经术治疗肺动脉高压的发展历程
Manasi Tannu,Richard A Krasuski
Manasi Tannu
Pulmonary arterial hypertension (PAH) is a progressive, life-limiting disease. Despite significant medical progress over the last three decades, the prognosis of PAH remains poor. PAH is associated with sympathetic nervous system over-stimu...
Technical Considerations for Performing Safe and Effective Balloon Pulmonary Angioplasty in Patients with Chronic Thromboembolic Pulmonary Hypertension [0.03%]
慢性血栓性肺动脉高压患者球囊肺动脉成形术安全及有效实施的技术要点
Kazuya Hosokawa,Yuzo Yamasaki,Kohtaro Abe
Kazuya Hosokawa
Chronic thromboembolic pulmonary hypertension (CTEPH) is a late complication of acute pulmonary thromboembolism owing to incomplete clot dissolution in pulmonary artery. Pulmonary endarterectomy is the first-line treatment for CTEPH. Howeve...