Kassem Farhat,Sunny S Po,Stavros Stavrakis
Kassem Farhat
The autonomic nervous system plays a central role in the pathogenesis of arrhythmias. Preclinical and clinical studies have demonstrated the therapeutic effect of neuromodulation at multiple anatomic targets across the neurocardiac axis for...
Asad Khan,Henry D Huang,Tolga Aksu
Asad Khan
Catheter-based neuromodulation of intrinsic cardiac autonomic nervous system is increasingly being used to improve outcomes in patients with vasovagal syncope and bradyarrhythmias caused by vagal overactivity. However, there is still no con...
Mohamed Zuhair,Daniel Keene,Prapa Kanagaratnam et al.
Mohamed Zuhair et al.
Percutaneous neuromodulation is emerging as a promising therapeutic approach for atrial fibrillation (AF). This article explores techniques such as ganglionated plexi (GP) ablation, and vagus nerve stimulation, pinpointing their potential i...
The Role of the Autonomic Nervous System as Both "Trigger and "Substrate" in Atrial Fibrillation [0.03%]
自主神经系统的双重角色：“触发因素”和“基础病变”在房颤中的作用
Varun Malik,Dominik Linz,Prashanthan Sanders
Varun Malik
Several complex mechanisms, working alone, or together, initiate and maintain atrial fibrillation (AF). At disease onset, pulmonary vein-atrial triggers, producing ectopy, predominate. Then, as AF progresses, a shift toward substrate occurs...
Pathophysiologic Mechanisms in Cardiac Autonomic Nervous System and Arrhythmias [0.03%]
心脏自主神经系统的病理生理机制及心律失常
Abdullah Sarkar,Olujimi A Ajijola
Abdullah Sarkar
The autonomic nervous system, including the central nervous system and the cardiac plexus, maintains cardiac physiology. In diseased states, autonomic changes through neuronal remodeling generate electrical mechanisms of arrhythmia such as ...
Liane A Arcinas,Carlos A Morillo,Robert S Sheldon et al.
Liane A Arcinas et al.
The mechanism of vasovagal syncope (VVS) is multifaceted and involves a delicate balance within the autonomic nervous system (ANS). This review delves into the complex interplay between the ANS and VVS, elucidating the pivotal role that aut...
Jacquie R Baker,Rashmin Hira,Jaiden Uppal et al.
Jacquie R Baker et al.
This review explores standardized clinical assessments for evaluating autonomic nervous system function. Here, we emphasize components of the autonomic medical history as the first pivotal test of the autonomic assessment. We further focus ...
Peter Hanna,Jeffrey L Ardell
Peter Hanna
Cardiac control is mediated via nested-feedback reflex control networks involving the intrinsic cardiac ganglia, intra-thoracic extra-cardiac ganglia, spinal cord, brainstem, and higher centers. This control system is optimized to respond t...
Robert Lemery
Robert Lemery
The contemporary history of the cardiac autonomic nervous system includes early descriptions of neuroanatomy in the 19th century, followed by an understanding of the physiologic determinants of neurocardiology in the 20th century. Neurology...
Luigi Di Biase,Emily P Zeitler
Luigi Di Biase