Rémy L M Mostard,Vivienne Kahlmann,Viresh A Jagesar et al.
Rémy L M Mostard et al.
The clinical presentation and both the nature and severity of organ involvement are highly heterogeneous and are influenced by ethnic, genetic, and geographic factors. Establishing the diagnosis can be challenging due to the wide spectrum o...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Apr 22:170:D8845. DOI: 2026
Charlotte S van den Aardwegh,Willemieke S F J Tummers,C E J Sloots
Charlotte S van den Aardwegh
Prenatal ultrasound showed an abdominal mass in a female foetus. During clinical examination of the neonate after birth, a bulging mass was visible at the introitus. The urethra and anus were patent, confirming the diagnosis of an imperfora...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Apr 22:170:D8730. DOI: 2026
Nynke L Rauwerda,Mette H Bakker
Nynke L Rauwerda
Chronic insomnia is a common condition that significantly burdens patients and increases the risk of various comorbidities. Cognitive Behavioral Therapy for Insomnia (CBT-I) is the recommended first-line treatment and has shown strong, long...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Apr 14:170:D8708. DOI: 2026
Ilja van Lingen,Stefanie Slot,Marije M G Krul et al.
Ilja van Lingen et al.
A patent foramen ovale (PFO) is present in approximately 25-30% of adults and is usually asymptomatic. However, under conditions of elevated right heart pressure, a PFO can enable right-to-left shunting, allowing venous thrombi to enter the...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Apr 15:170:D8798. DOI: 2026
Madelon M E Riem,Lisa Loheide-Niesmann,Roseriet Beijers et al.
Madelon M E Riem et al.
Objective: We examined whether intranasal oxytocin affects maternal caregiving, mood, and stress physiology in mothers with postpartum depression (PPD). D...
Randomized Controlled Trial
Nederlands tijdschrift voor geneeskunde. 2026 Apr 16:170:D8852. DOI: 2026
Michelle W J Heijman,Calin Popa,Bart J F van den Bemt
Michelle W J Heijman
Drug repurposing is often presented as a cost-effective strategy to accelerate the development of new therapies. The underlying rationale is that the safety, pharmacokinetics and pharmacodynamics, and mechanism of action of these drugs are ...
Elodie F Holwerda,Eefje A Hamminga
Elodie F Holwerda
A three-year-old boy presented with asymptomatic facial papules. Biopsy revealed dermal histiocyte proliferation. Based on clinical and histological findings, benign cephalic histiocytosis - a rare, self-limiting condition of infancy - was ...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Apr 8:170:D8755. DOI: 2026
Maria E T C van den Muijsenbergh,Charles C Obihara,Bahar Golchehr
Maria E T C van den Muijsenbergh
In comparison with others, migrants more often suffer from chronic illnesses and conditions that are less familiar to physicians trained in the Netherlands. At the same time access to care can be hampered by language barriers and care that ...
[Two patients with CC9 intoxication: unexpected symptoms of a novel synthetic cannabinoid] [0.03%]
两例CC9中毒患者：新型合成大麻素的意外症状
Denne A Scharink,Hugo C Hoogeveen,Daan Vlot et al.
Denne A Scharink et al.
Background: Hexahydrocannabinol-C9 (CC9) is a novel synthetic cannabinoid with largely unknown toxicity and clinical effects. Case description: ...
Case Reports
Nederlands tijdschrift voor geneeskunde. 2026 Mar 31:170:D8810. DOI: 2026
Karin M Burgerhout,Nienke Hoekstra,Leontien M van Ravesteyn et al.
Karin M Burgerhout et al.
The diagnosis of ADHD remains shrouded in controversy, resulting in alarming reports in (social) media. Danger of underdiagnosis, risk of overdiagnosis, and medicalization of social problems are all mentioned. The diagnostic uncertainty is ...