Background Mucosal Inflammation Affects Colorectal Cancer Prognosis in Ulcerative Colitis: A Nationwide, Multicenter Study [0.03%]
背景黏膜炎症影响溃疡性结肠炎相关结直肠癌的预后：一项全国多中心研究
Akiyoshi Ikebata,Koji Okabayashi,Motoi Uchino et al.
Akiyoshi Ikebata et al.
Background and aims: Chronic background mucosal inflammation contributes to colorectal cancer (CRC) development in ulcerative colitis (UC), but its prognostic impact is unclear. We evaluated whether background mucosal inf...
Cost-effective inflammatory bowel disease flare pathway with nurse-led triage and rapid access intestinal ultrasound reduces hospital resource use with high patient satisfaction [0.03%]
以护士主导的分诊和快速肠道超声检查为核心的结肠炎复发诊疗路径可节省医疗资源且患者满意度高
Richard Gareth Fernandes,Emi Khoo,Heidi Jensen Harris et al.
Richard Gareth Fernandes et al.
Background: Timely treatment of inflammatory bowel disease (IBD) flares improves outcomes, but quick differentiation from other symptom causes is challenging. We implemented a clinical care pathway (CCP) using protocolise...
Efficacy of 5-Aminosalicylic Acid Continuation versus Discontinuation in Patients with Ulcerative Colitis Escalated to Advanced Therapy: A Systematic Review and Meta-Analysis of Adjusted Effect Estimates [0.03%]
溃疡性结肠炎升级至生物制剂或Janus激酶抑制剂治疗后的5氨基水杨酸维持疗法 vs 停止使用5氨基水杨酸：系统评价和荟萃分析调整效应估计值
Hyun Hee Sul,Douglas Mesadri Gewehr,Hara Kang et al.
Hyun Hee Sul et al.
Background and aims: The benefit of continuing 5-aminosalicylates (5-ASA) in patients with ulcerative colitis (UC) escalated to advanced therapies remains uncertain. We conducted a systematic review and meta-analysis to e...
Real-world evaluation of MRI fistula volume as a radiological biomarker of disease activity in perianal fistulising crohn's disease [0.03%]
磁共振成像造瘘体积在肛门括约肌外瘘管型克罗恩病活动度影像生物标记物中的真实世界评价研究
Easan Anand Mr,Sulak Anandabaskaran Dr,Theo Pelly Mr et al.
Easan Anand Mr et al.
Background: The TOpClass classification for perianal fistulising Crohn's disease (pfCD) facilitates tailored treatment to clinical state and patient goals. MRI is central to pfCD assessment, but existing indices are limit...
Apples and Oranges? Comparison of Early Ileocolic Resection and Medical Treatment for Crohn's Disease: A Systematic Review and Meta-analysis [0.03%]
苹果和橘子？早期回肠造口术与克罗恩病的药物治疗比较：系统性回顾及Meta分析
Mads Damsgaard Wewer,Johan Burisch,Pär Myrelid et al.
Mads Damsgaard Wewer et al.
Cumulative Incidence and Risk Factors for Advanced Neoplasia following Inflammatory Bowel Disease-Related Low-Grade Dysplasia: A Danish Nationwide Cohort Study [0.03%]
一项丹麦全国队列研究：炎症性肠病相关低级别上皮内瘤变后高级别肿瘤的发病率及危险因素分析
Jesper Winkler Andersen,Frederikke Schønfeldt Troelsen,David Haldrup et al.
Jesper Winkler Andersen et al.
Background: Individuals with inflammatory bowel disease (IBD) and related low-grade dysplasia (LGD) have an elevated risk of developing high-grade dysplasia (HGD) or colorectal cancer (CRC). The magnitude of this risk and...
Inflammatory Bowel Disease therapies and Demyelinating Diseases: A Practical Guide to Therapeutic Benefit and Risk [0.03%]
炎症性肠病疗法和脱髓鞘疾病：治疗利弊风险实用指南
Sailish Honap,Marc Debouverie,Massimo Filippi et al.
Sailish Honap et al.
Demyelinating diseases, particularly multiple sclerosis (MS), present a unique therapeutic challenge in the management of inflammatory bowel disease (IBD). Although rare, the co-occurrence of IBD and demyelinating disorders is well-document...
Development and validation of a novel multimodal deep learning model integrating histopathology, radiology, and clinical data to predict primary non-response to infliximab in patients with crohn's disease [0.03%]
一种新颖的多模态深度学习模型的发展与验证，该模型整合病理学、放射学和临床数据以预测克罗恩病患者对英夫利昔单抗的一级原发性无反应性
Yu Wang,Haipeng Wang,Xiaomin Wu et al.
Yu Wang et al.
Background and aims: Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. While infliximab (IFX) offers significant benefits, 10-30% of patients remain non-responders initially. This stu...
The Complex Relationship Between Physical Activity and Fatigue with Socioeconomic Status, and Mental Health Factors in Individuals with IBD [0.03%]
炎症性肠病患者中体力活动和疲劳与社会经济状况及心理健康因素之间复杂关系的研究
Casandra Dolovich,Sydney Chochinov,Gia Ly et al.
Casandra Dolovich et al.
Background: We aimed to assess to what extent socioeconomic status (SES) and elevated symptoms of anxiety and depression predict low physical activity (PA), and high fatigue among individuals with IBD. ...