Effect of co-axially hybridized gene targets on hybridization efficiency of microarrayed DNA probes [0.03%]
共轴杂交基因目标对微阵列DNA探针杂交效率的影响
Kai Ren Jiang,Jie-Len Huang,Chia-Chun Chen et al.
Kai Ren Jiang et al.
The effect of relative size of two co-axially hybridized gene targets on the hybridization efficiency was studied for two DNA probe configurations and various probe concentrations. Each of two sets of microarrayed probes contained a pair of...
Establishment of a screening protocol for identification of aminopeptidase N inhibitors [0.03%]
天冬氨酰胺肽酶N抑制剂的筛选体系建立与应用研究
Miaomiao Niu,Fengzhen Wang,Fang Li et al.
Miaomiao Niu et al.
Inhibitors of aminopeptidase N (APN) have been thought as potential drugs for the treatment of tumor angiogenesis, invasion and metastasis and a considerable number of APN inhibitors have been reported recently. To clarify the essential str...
Structural bioinformatics analysis of free cysteines in protein environments [0.03%]
蛋白质环境中自由半胱氨酸的结构生物信息学分析
Sheau Ling Ho,Andrew H-J Wang
Sheau Ling Ho
Cysteine has been considered as a "hydrophilic" amino acid because of its pK a and its ability to form (weak) hydrogen bonds. However, cysteines are found mostly in hydrophobic environments, either in S-S (disulphide) form or in free cystei...