A Prospective Study on the Role of Strain Echocardiography in Detecting Early Radiation-induced Cardiotoxicity in Left-sided Breast Cancer Patients [0.03%]
应变超声心动图在左侧乳腺癌患者早期放疗心脏毒性的检测中的作用的前瞻性研究
Areti Gkantaifi,Christodoulos Papadopoulos,Maria Toumpourleka et al.
Areti Gkantaifi et al.
Introduction: Breast cancer radiotherapy has a clear benefit for both long-term survival and local control rate. However, healthy surrounding normal tissues, including the heart and lungs, can negatively impact a patient'...
Transformative Paths: Preclinical Drug Formulation and Delivery Approaches in Development [0.03%]
转型之路：开发中的药物制剂与输送方法
Deepshi Arora,Anjali Sharma,Prabhjot Kaur et al.
Deepshi Arora et al.
This comprehensive review explores the multifaceted landscape of preclinical drug development, encompassing crucial stages, regulatory intricacies, Investigational New Drug (IND) submissions, and innovative formulation strategies. Delving i...
Sexual Dysfunctions in Chronic Liver Diseases: A Narrative Review on Prevalence and Putative Pathophysiologic Mechanisms [0.03%]
慢性肝病性功能障碍：患病率及潜在病理生理机制的叙述性综述
Kateryna Priadko,Felice Crocetto,Carmine Sciorio et al.
Kateryna Priadko et al.
Background: Chronic liver diseases are associated with impaired sex hormone metabolism and downregulation of the hypothalamic-pituitary-gonadal axis. Clinically, this may manifest as a variety of sexual disorders, such as...
Cybersecurity and Compliance in Clinical Trials: The Role of Artificial Intelligence in Secure Healthcare Management [0.03%]
临床试验中的网络安全与合规性：人工智能在安全医疗管理中的作用
Virendra S Gomase,Arjun P Ghatule,Rupali Sharma et al.
Virendra S Gomase et al.
Rapid healthcare digitization has created both previously unheard-of potential and serious data management weaknesses, especially in clinical trials. Artificial Intelligence (AI) offers innovative approaches to enhancing cybersecurity and e...
The Importance of Vaccines in Preventing Impending Alzheimer's Epidemic [0.03%]
疫苗在预防迫在眉睫的阿尔茨海默病流行中的重要性
Siddhant Tripathi,Yashika Sharma,Dileep Kumar
Siddhant Tripathi
The use of antibodies to neutralize cytotoxic soluble amyloid-β aggregates rather than remove plaque has raised cautious hope since the monoclonal antibody BAN2401 seems to halt the course of prodromal Alzheimer's Disease (AD). By immobili...
Wound Healing Complications after Neoadjuvant Radiotherapy Combined with Targeted Therapies in Soft Tissue Sarcoma Patients [0.03%]
新辅助放疗联合靶向治疗后软组织肉瘤患者的伤口并发症
Nikolaos S Georgopoulos,Maria Tolia,Annita Boulouta et al.
Nikolaos S Georgopoulos et al.
Introduction/objective: Significant advancements have been achieved with the use of targeted molecular therapies for the treatment of Soft Tissue Sarcomas (STS). However, data remains scarce about the potential benefits a...
The Effect of Foot Reflexology on the Sexual Function of Lactating Women: A Randomized Clinical Trial [0.03%]
足部反射区按摩对哺乳期女性性功能影响的随机临床试验
Zahra Ghanbari,Mahboubeh Valiani,Shahnaz Kohan
Zahra Ghanbari
Background: Sexual health is an essential part of women's lives at different ages. Pregnancy, childbirth, and breastfeeding can affect women's sexual function by inducing biological, psychological, and social changes. Due...
Iram Shabir,Christina Foster
Iram Shabir
Immune checkpoint inhibitor therapy has become the established method of treatment for various types of cancers, consequently introducing a spectrum of side effects referred to as immune- mediated adverse events, affecting almost every orga...
Fully Covered Self-Expandable Metal Stents for the Treatment of Leak after Oncologic Gastroesophageal Surgery: A Cohort Study [0.03%]
用于治疗食管胃癌术后漏的全覆膜自扩式金属支架：一项队列研究
Carmelo Luigiano,Milena Di Leo,Marco Magistroni et al.
Carmelo Luigiano et al.
Background: Anastomotic leakages are one of the most frequent complications of gastroesophageal surgery with a high mortality. Objective: ...
Critical Analysis of Non-profit Clinical Trials: Three Years of Activity at the Clinical Trials Office [0.03%]
临床试验办公室三年活动的批判分析：来自临床试验办公室的观点
Diego Alejandro Dri,Marta De Cata,Maria Carafa et al.
Diego Alejandro Dri et al.
Introduction: Non-profit clinical trials submitted for authorization over three years to the Clinical Trials Office of the Italian Medicines Agency were reviewed and critically analyzed. ...