Adopting extensive intra-operative peritoneal lavage (EIPL) as the standard prophylactic strategy for peritoneal recurrence [0.03%]
采用广泛的术中腹腔冲洗(EIPL)作为预防腹膜复发的标准策略
Shinya Shimada,Masafumi Kuramoto,Takashi Marutsuka et al.
Shinya Shimada et al.
EIPL (extensive intra-operative peritoneal lavage) therapy was developed as a prophylactic strategy for peritoneal recurrence, with the goal of improving the quality of life and survival span for advanced gastric cancer patients with perito...
Neuroinflammation and ageing: current theories and an overview of the data [0.03%]
神经炎症和衰老:当前理论与数据概述
Vincenzo Pizza,Anella Agresta,Cosimo W DAcunto et al.
Vincenzo Pizza et al.
The increase in the average lifespan and the consequent proportional growth of the elderly segment of society has furthered the interest in studying ageing processes. Ageing may be considered a multifactorial process derived from the intera...
The current status of cryotherapy and high-intensity focused ultrasound in the treatment of low-grade prostate cancer [0.03%]
低温治疗和高强度聚焦超声在低危前列腺癌治疗中的应用现状
Vassilis J Siomos,Al Barqawi
Vassilis J Siomos
As a result of widespread serum prostate-specific antigen (PSA) screening and prostate cancer awareness, the detection of low-grade prostate cancer has increased. At the moment, it is unclear how to treat patients in this population. Thus, ...
Treatment options for cystic fibrosis: state of the art and future perspectives [0.03%]
囊性纤维化的治疗选项:现状与未来展望
Edmund H Sears,Eric J Gartman,Brian P Casserly
Edmund H Sears
Cystic fibrosis (CF) is an autosomal recessive disorder characterized by chronic lung and sinus disease, impaired mucociliary clearance (leading to recurrent pulmonary infection), pancreatic insufficiency, elevated sweat chloride levels and...
Is there evidence to support the use of direct Factor Xa inhibitors in coronary artery disease? [0.03%]
冠状动脉疾病患者使用直接Xa因子抑制剂的证据支持吗?
Sheila Anne Doggrell
Sheila Anne Doggrell
As coronary artery disease (CAD) remains a leading cause of death in the world, the development of anti-coagulants to prevent CAD progressing to myocardial infarction and death is a high priority. A number of direct Factor Xa (FXa) inhibito...
Current strategies to achieve further cardiac and renal protection through enhanced renin-angiotensin-aldosterone system inhibition [0.03%]
目前通过增强肾素血管紧张素醛固酮系统抑制进一步实现心脏和肾脏保护的策略
J Alfie,L S Aparicio,G D Waisman
J Alfie
An incomplete inhibition of the renin angiotensin aldosterone system (RAAS) may be responsible for the residual organ damage and event rate that still occur in spite of an apparent blood pressure control in patients with hypertension, diabe...
Design and endpoints of clinical and translational trials in advanced colorectal cancer. a proposal from GROUP Español Multidisciplinar en Cancer Digestivo (GEMCAD) [0.03%]
结直肠癌临床与转化试验的设计及终点指标.GEMCAD建议报告
Gemma Carrera,Xabier Garcia-Albeniz,Juan Ramón Ayuso et al.
Gemma Carrera et al.
Meta-analytic reviews of Randomized Clinical Trials (RCT) have reached contradictory conclusions regarding the benefit of medical interventions in Advanced Colorectal Cancer (ACRC). Surrogate markers of survival benefit, such as response ra...
Recent clinical evidence for the treatment of osteoarthritis: what we have learned [0.03%]
最近的临床证据:我们从骨关节炎治疗中了解了什么?
Nidhi Sofat,Iain Beith,P G Anilkumar et al.
Nidhi Sofat et al.
Osteoarthritis (OA) is a chronic arthritis affecting growing numbers of the ageing population. Patients diagnosed with OA place a large burden on access to healthcare services, including primary care, prescription of analgesic drugs, physio...
The role of lipoprotein-associated phospholipase A2 (Lp-PLA₂) in cardiovascular disease [0.03%]
脂蛋白相关磷脂酶A2(Lp-PLA₂)在心血管疾病中的作用
Ignatios Ikonomidis,Christos A Michalakeas,John Lekakis et al.
Ignatios Ikonomidis et al.
Lipoprotein-associated Phospholipase A2 (Lp-PLA(2)) is an enzyme that belongs to the A2 Phospholipase superfamily and is produced by inflammatory cells that are involved in the process of atherogenesis. Even though there is controversy in c...
Melanoma: the radiotherapeutic point of view; review of the current literature [0.03%]
皮肤黑色素瘤放射治疗综述文献评论文章
A Zygogianni,G Kyrgias,J Kouvaris et al.
A Zygogianni et al.
Surgery remains the mainstay of melanoma therapy at all sites. Melanoma is widely believed to be a radioresistant tumor, a misconception that has historically led to the limited use of RT for its treatment. We searched pubmed from 1978 unti...