Topical Application of Olive Oil in Preventing Pressure Injuries Among Hospitalized Patients with Mobility Limitations: A Cluster Randomized Trial in the United Arab Emirates [0.03%]
阿拉伯联合酋长国住院患者限mobility limitations动性压力损伤预防中橄榄油外用集群随机试验
Maraim Mohammed Saeed Almesmari,Rose Ekama Ilesanmi,Mona Gamal Mohamed
Maraim Mohammed Saeed Almesmari
Introduction: Pressure injuries (PIs) pose a significant threat to the safety of hospitalized, mobility-compromised patients globally. Olive oil has shown promising results in preventing PIs due to its high concentrations...
The Role of Animal Models in Huntington's Disease Clinical Trials: Decoding Genetic, Non-Genetic, and Molecular Pathways [0.03%]
亨廷顿舞蹈病临床试验中动物模型的作用：解码基因、非基因和分子途径
Aarti A Bhimanwar,Aditi S Kulkarni,Virendra S Gomase
Aarti A Bhimanwar
Background: Huntington's disease (HD) is a neurodegenerative disorder due to a CAG trinucleotide repeat expansion in the HD gene. Animal models have been instrumental in revealing the genetic and molecular bases of HD. Wh...
Inter-rater Reliability and Accuracy of NBI Score for Activity Evaluation in Ulcerative Colitis [0.03%]
内镜下染色评分评估溃疡性结肠炎活动度的评分者间可靠性及准确性
Gianpiero Stefanelli,Marco Valvano,Annalisa Capannolo et al.
Gianpiero Stefanelli et al.
Background: Colonoscopy is a critical tool for the management of Ulcerative Colitis (UC). In this study, we aim to explore the accuracy of Virtual Chromoendoscopy (VCE) using Narrow Banding Imaging (NBI), and magnificatio...
Evaluating the Impact of Lifestyle Interventions on Health Outcomes in Breast Cancer Survivors: A Systematic Review [0.03%]
评估生活方式干预对乳腺癌幸存者健康结果的影响：系统回顾
Gulafshan Fatima,Tuba Razi,Sana Jameel et al.
Gulafshan Fatima et al.
Background: Lifestyle interventions have been increasingly studied for their potential to improve health outcomes in breast cancer survivors. However, the relative effectiveness of these interventions remains unclear. ...
Assessing the Efficacy of Small Molecule Drugs in Hutchinson-Gilford Progeria Syndrome: A Review of Clinical Trials [0.03%]
亨特-吉尔福德早衰综合征中小分子药物疗效的临床试验评估
Drishti Desai,Charmi Jyotishi,Suresh Prajapati et al.
Drishti Desai et al.
Hutchinson-Gilford Progeria Syndrome (HGPS), or progeria, is an exceptionally rare disorder characterized by premature aging. It is primarily caused by a c.1824C>T point mutation in exon 11 of the LMNA gene, though other rare pathogenic var...
ICU Mortality Prediction Using XGBoost-based Scoring Systems: A Study from a Developing Country [0.03%]
基于XGBoost的评分系统在重症监护病房死亡率预测中的应用：一项发展中国家的研究
Reema Karasneh,Sayer Al-Azzam,Karem H Alzoubi et al.
Reema Karasneh et al.
Background: Accurate mortality prediction in intensive care units (ICUs) is essential for enhancing patient outcomes and optimizing healthcare resource allocation. Traditional scoring systems, such as APACHE, APACHE II, a...
John Giridharan Ivr,R Srinivasan
John Giridharan Ivr
Introduction: Brexit has significantly altered the regulatory landscape for pharmaceuticals, with the UK no longer under the European Medicines Agency (EMA). The UK's Medicines and Healthcare products Regulatory Agency (M...
Comparative Review of Clinical Trial Regulations in Different Countries: Current Scenario and Future Prospect [0.03%]
多国临床试验法规比较分析：现状与未来展望
Mansi Sharma,Manan Grover,Navneet Sharma et al.
Mansi Sharma et al.
Introduction/objective: Clinical trial regulations (CTR) are essential for ensuring the safety, efficacy, and ethical conduct of drug development. However, the regulatory frameworks governing these trials vary significant...
A Review of Software in Clinical Trials: FDA Regulatory Frameworks and Addressing Challenges [0.03%]
临床试验中软件的监管框架及挑战应对综述——基于美国食品药品监督管理局视角
Simran Dixit,Deepti Sharma,Navneet Sharma et al.
Simran Dixit et al.
An essential tool for assessing the efficacy and safety of novel therapies and interventions is the clinical trial. They are crucial for understanding disease causes, treatment effectiveness, and patient care processes. However, traditional...
Colorectal Cancer Screening Modalities Among Saudi Population: Significant Predictors [0.03%]
沙特人口中的结直肠癌筛查方式及重要影响因素
Mohammad Bukhetan Alharbi
Mohammad Bukhetan Alharbi
Introduction: Understanding the public perception of colorectal cancer screening is crucial since early diagnosis lowers mortality rates associated with this type of cancer. ...