CD20 antigen imaging with ¹²⁴I-rituximab PET/CT in patients with rheumatoid arthritis [0.03%]
~^{124}I-利妥昔单抗PET/CT显像在类风湿关节炎患者中的应用：靶向CD20抗原
L Tran,A D R Huitema,M H van Rijswijk et al.
L Tran et al.
Introduction: Visualization of the CD20-antigen expression could provide a tool to localize sites of inflammation and could be of additive value in the diagnosis, and subsequently, in the treatment follow-up of patients w...
Generation of novel recombinant antibodies against nitrotyrosine by antibody phage display [0.03%]
利用噬菌体展示技术获得新型抗硝基酪氨酸抗体
Danielle Hof,Seraina Cooksley-Decasper,Sandra Moergeli et al.
Danielle Hof et al.
Nitrotyrosine is a posttranslational protein modification that occurs under oxidative and nitrosative stress, and plays an important role in numerous pathological conditions. To analyse nitrotyrosine formation several commercial monoclonal ...
The pharmacokinetics of ¹²⁴I-rituximab in patients with rheumatoid arthritis [0.03%]
124I-rituximab在类风湿关节炎患者中的药代动力学特征研究
L Tran,W V Vogel,M Sinaasappel et al.
L Tran et al.
Rheumatoid arthritis is a destructive inflammatory joint disorder. Pre- and mature B-cells, characterized by CD20 antigen expression, play an important role in the inflammatory process. Rituximab, a chimeric monoclonal antibody against the ...
Antiphospholipid and other autoantibodies in a cohort of habitual aborters and healthy multiparous women in Jamaica [0.03%]
抗磷脂抗体和其他自身抗体在牙买加习惯性流产者和健康经产妇队列中的研究
K Roye-Green,J Frederick,G Wharfe et al.
K Roye-Green et al.
Blood samples from 50~women who had had recurrent spontaneous abortions and 135 healthy multiparous women were investigated for anticardiolipin (aCL) antibodies and anti-β₂ Glycoprotein 1 (anti-β₂ GP1) dependent aCL antibodies by enzyme...
A fully human monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB) with functional activity in vitro and in vivo [0.03%]
一种完全人类化的金黄色葡萄球菌铁调节表面决定簇B(IsdB)单克隆抗体及其体内外功能活性
Tim Ebert,Sharon Smith,Greg Pancari et al.
Tim Ebert et al.
A fully human monoclonal antibody (CS-D7, IgG1) specific for the iron regulated surface determinant B (IsdB) of Staphylococcus aureus was isolated from the Cambridge Antibody Technology (CAT) scFv antibody library. As compared to previously...
Preparation and in vitro evaluation of 111In-CHX-A"-DTPA-labeled anti-VEGF monoclonal antibody bevacizumab [0.03%]
贝伐单抗(CHX-A-DTPA)-111铟的制备及其体外评价研究报告
Seyed Jalal Hosseinimehr,Anna Orlova,Vladimir Tolmachev
Seyed Jalal Hosseinimehr
Bevacizumab is a humanized monoclonal antibody that binds to vascular endothelial growth factor (VEGF) and prevents tumor angiogenesis. Radionuclide imaging using radiolabeled bevacizumab might be useful for selection of patients for anti-V...
Epitope analysis of peanut allergen Ara h1 with human monoclonal IgM antibody clone #86 [0.03%]
人单克隆IgM抗体克隆86的花生过敏原Ara h1表位分析
Hiroshi Shinmoto,Mio Takeda,Yuji Matsuo et al.
Hiroshi Shinmoto et al.
A human-mouse hybridoma clone #86 secreting IgM-class human monoclonal antibody to peanut allergen protein Ara h1 was newly established. To detect an antibody-binding sequence (epitope) on Ara h1, the monoclonal antibody #86 was reacted wit...
IgG isotype, glycosylation, and EGFR expression determine the induction of antibody-dependent cellular cytotoxicity in vitro by cetuximab [0.03%]
伊鲁西玛布诱导抗体依赖的细胞毒性作用的体外研究及其与表皮生长因子受体表达和免疫球蛋白G亚类及糖基化的关系
Dipa Patel,Xuemei Guo,Stanley Ng et al.
Dipa Patel et al.
Purpose: To evaluate the antibody-dependent cellular cytotoxicity (ADCC) of cetuximab, an anti-epidermal growth factor receptor (EGFR) IgG1 antibody, in vitro. ...
A new radiopharmaceutical compound (131I-PR81) for radioimmunotherapy of breast cancer: labeling of antibody and its quality control [0.03%]
一种新的放射性药物化合物(131I-PR81)用于乳腺癌的免疫治疗：抗体标记及其质量控制研究
J Mohammadnejad,M J Rasaee,M H Babaei et al.
J Mohammadnejad et al.
PR81 is a monoclonal antibody that binds with high affinity to MUC1, which is over expressed on breast and other tumors. The objective of this study was to evaluate the application of this antibody against MUC1 as a radioimmunotherapeutical...
Selection of naturally occurring autoantibodies to interleukin-18 from phage display library [0.03%]
从噬菌体展示文库中筛选天然存在的抗IL-18自身抗体
M A Vikhrova,M V Shveygert,E A Khrapov et al.
M A Vikhrova et al.
Four unique phage single-chain variable fragments (scFvs) to recombinant human interleukin 18 (IL-18) has been selected from a naïve combinatorial library of human scFvs. Binding of unique phage antibodies with IL-18 was tested by ELISA an...