Mohammad Taheri,Shirin Nemati,Abolfazl Movafagh et al.
Mohammad Taheri et al.
Background: Multiple sclerosis (MS) as an autoimmune disorder in which the insulating covers of neurons in the Central Nervous System are destructed. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an i...
Investigation of the correlation between some immune system and biochemical indicators in patients with type 2 diabetes [0.03%]
2型糖尿病患者某些免疫系统和生化指标的相关性调查分析
Mohammad Mahdi Eftekharian,Jamshid Karimi,Mojgansadat Safe et al.
Mohammad Mahdi Eftekharian et al.
Aims/introduction: Since changes in some immune system indicators such as leukocyte count and neutrophil to lymphocyte ratio in the blood and Inflammation is directly in relation with the pathogenesis of type 2 diabetes, ...
Frequency of viral infections and environmental factors in multiple sclerosis [0.03%]
病毒感染频率及环境因素在多发性硬化病中的作用
Mohammad Mahdi Eftekharian,Masoud Sabouri Ghannad,Mohammad Taheri et al.
Mohammad Mahdi Eftekharian et al.
Objectives: Multiple sclerosis (MS) is a complicated disease which occurs due to relationship between genes and environmental factors that causes tissue damage by autoimmune mechanisms.We investigated and illustrated the ...
High-resolution analysis of the B cell repertoire before and after polyethylene glycol fusion reveals preferential fusion of rare antigen-specific B cells [0.03%]
高分辨率B细胞受体分析揭示低频抗原特异性B细胞的聚乙二醇诱导融合率较高
Axel R S X Dubois,Jean-Philippe Buerckert,Regina Sinner et al.
Axel R S X Dubois et al.
Objective: The hybridoma technology is one of the most important advances in clinical immunology. Little is known about the differences between the antibodies produced during the in vivo immune response and those recovere...
Design and construction of immune phage antibody library against Tetanus neurotoxin: Production of single chain antibody fragments [0.03%]
破伤风神经毒素免疫噬菌体抗体库的构建及单链抗体片段的产生
Sanam Sadreddini,Mehrnosh Seifi-Najmi,Babollah Ghasemi et al.
Sanam Sadreddini et al.
Background: Tetanus neurotoxin (TeNT) is composed of a light (LC) and heavy chain (HC) polypeptides, released by anaerobic bacterium Clostridium tetani and can cause fatal life-threatening infectious disease. Toxin HC and...
Amjad Hayat Khan,Esmaeil Sadroddiny
Amjad Hayat Khan
Monoclonal antibodies (mAbs) are the leading class of targeted therapeutics and remarkably effective in addressing autoimmune diseases, inflammations, infections, and various types of cancer. Several mAbs approved by US food and drug admini...
Prevalence of Hepatitis B surface antigen among biomedical students of African descent in Usmanu Danfodiyo University, Sokoto, Nigeria [0.03%]
尼日利亚苏科托州乌斯曼·丹福迪约大学非洲裔生物医学专业学生乙型肝炎表面抗原患病率调查
A N Okwesili,F U Onuigwe,K Ibrahim et al.
A N Okwesili et al.
Background: Hepatitis B (HB) is a serious global public health problem that put health professionals particularly at risk. Objective: T...
Andrew Hiatt,Michael Pauly,Kevin Whaley et al.
Andrew Hiatt et al.
This review describes the history of Ebola monoclonal antibody (mAb) development leading up to the recent severe Ebola outbreak in West Africa. The Ebola virus has presented numerous perplexing challenges in the long effort to develop thera...
Somanath Kallolimath,Herta Steinkellner
Somanath Kallolimath
Human immunoglobulins circulate as highly heterogeneously glycosylated mixture of otherwise homogeneous protein backbones. A series of studies, mainly on IgG, have unequivocally proven that antibodies modulate their effector function throug...