Development of nanoparticle adjuvants to potentiate the immune response against diphtheria toxoid [0.03%]
用于增强白喉毒素免疫反应的纳米颗粒佐剂的研发
Fatimah M Alshanqiti,Saad Berki Al-Masaudi,Ahmed M Al-Hejin et al.
Fatimah M Alshanqiti et al.
Background: Over the years, diphtheria was known as contagious fatal infection caused by Corynebacterium diphtheria that affects upper respiratory system. The spread of diphtheria epidemic disease is best prevented by vac...
Shridhar C Ghagane,Sridevi I Puranik,Siew Hua Gan et al.
Shridhar C Ghagane et al.
With the flourishing of innovation in drug discovery into a new era of personalized therapy, the use of monoclonal antibodies (mAbs) in the treatment of various ailments lies at the forefront. Major improvements in genetic sequencing and bi...
Neutralizing activity and safety of human monoclonal antibodies against hepatitis C virus [0.03%]
抗丙型肝炎病毒的人源单克隆抗体的中和活性及安全性研究
Camelia A Abdel Malak,Tawfeek H Abelhafez,Ashraf A Tabll et al.
Camelia A Abdel Malak et al.
Aim: Assessment of the neutralizing activity of human monoclonal antibodies against HCV and also study their safety in experimental small animals (Swiss mice). ...
Role of FSHR rs6165 and ESR2 rs4986938 polymorphisms in ovarian stimulation of Iranian women who underwent assisted reproduction treatment [0.03%]
FSHR基因rs6165和ESR2基因rs4986938多态性在伊朗女性体外受精促排卵中的作用
Maryam Kaviani,Sayyed Mohammad Hossein Ghaderian,Soheila Arefi et al.
Maryam Kaviani et al.
Background: Gonadotropin therapy was used to stimulate the ovary in infertile women who underwent assisted reproduction treatment (ART). Numerous studies indicated that infertile women showed different responses to gonado...
Ecotropic Viral Integration Site 5 (EVI5) expression analysis in multiple sclerosis patients [0.03%]
多发性硬化症患者EVI5表达分析
Mehrdokht Mazdeh,Mahnoosh Rahimi,Mohammad Mahdi Eftekharian et al.
Mehrdokht Mazdeh et al.
Background: Multiple sclerosis (MS) is a complex immune-related disorder of the central nervous system (CNS) in which dysregulation of different classes of T cells are involved. Variants in Ecotropic Viral Integration Sit...
Obtaining and characterization of monoclonal antibodies against recombinant extracellular domain of human epidermal growth factor receptor 2 [0.03%]
人源性表皮生长因子受体2重组型胞外域单克隆抗体的获取及鉴定
Nurgul Sarina,Sailau Abeldenov,Aigerim Turgimbayeva et al.
Nurgul Sarina et al.
Human epidermal growth factor receptor 2 (HER2) is an important biomarker for detection and treatment of different types of cancers such as breast, ovarian, stomach cancer. In this study, we developed a monoclonal antibody against the extra...
Ivan Babic,Elmar Nurmemmedov,Venkata M Yenugonda et al.
Ivan Babic et al.
Immunotherapy is now at the forefront of cancer therapeutic development. Gliomas are a particularly aggressive form of brain cancer for which immunotherapy may hold promise. Pritumumab (also known in the literature as CLNH11, CLN-IgG, and A...
Determining the IgM and IgG antibodies titer against HSV1, HSV2 and CMV in the serum of schizophrenia patients [0.03%]
精神分裂症患者血清HSV1、HSV2和CMV的IgM和IgG抗体滴度检测
Masome Mohagheghi,Mohammad Mahdi Eftekharian,Mohammad Taheri et al.
Masome Mohagheghi et al.
Schizophrenia is a destructive clinical syndrome with diverse mental pathologies. Different mechanisms and factors have a role in this disease. A possible mechanism is that teratogenic viruses cause brain changes and results in the disease ...
Investigating the exon 6 sequence changes of interleukin 7 receptor A (IL7RA) gene in patients with relapsing-remitting multiple sclerosis [0.03%]
复发缓解型多发性硬化患者IL7RA基因外显子6序列改变的研究
Mohammad Taheri,Arezou Sayad
Mohammad Taheri
Background: Interleukin 7 receptor alpha (IL7RA) gene that encodes a subunit of IL7 receptor has been reported to be associated with different immunologic disease. ...
Human Anti-Lipopolysaccharid (LPS) antibodies against Legionella with high species specificity [0.03%]
针对Legionella菌具有高种属特异性的抗脂多糖(LPS)人源单克隆抗体
Philipp Kuhn,Stefanie Thiem,Michael Steinert et al.
Philipp Kuhn et al.
Legionella are Gram-negative bacteria that are ubiquitously present in natural and man-made water reservoirs. When humans inhale aerosolized water contaminated with Legionella, alveolar macrophages can be infected, which may lead to a life-...