Optimized protocol for soluble prokaryotic expression, purification and refolding of the human inhibin α subunit, a cysteine rich peptide chain [0.03%]
人抑制素α亚基的一种半胱氨酸丰富的肽链的可溶性原核表达、纯化及复性的最佳方案
Sedighe Kolivand,Mahboobeh Nazari,Mohammad Hossein Modarressi et al.
Sedighe Kolivand et al.
Background: Inhibin A, a member of TGF-β superfamily, consists of α and β subunits. These subunits contain several cysteine residues in amino acid sequence that forms inter- and intra-subunits disulfide bonds. Due to t...
Association between HLA alleles and risk of celiac disease in Iranian patients [0.03%]
人白细胞抗原等位基因与伊朗患者乳糜泻风险之间的关系
Hamid Fallah,Mohammad Taghi Akbari,Sara Mirzajani et al.
Hamid Fallah et al.
Celiac disease (CD) is a common autoimmune disease that is manifested by inflammation of the small intestine and varying extra intestinal symptoms, also considered to be associated with human HLA-DQ genes. In this study, 40 patients of CD a...
Association between tumor necrosis factor-alpha gene rs1800629 (-308G/A) and rs361525 (-238G > A) polymorphisms and prostate cancer risk in an Iranian cohort [0.03%]
肿瘤坏死因子-α基因rs1800629（-308G / A）和rs361525（-238G> A）多态性与伊朗人群中前列腺癌风险之间的关联研究
Saeideh Alidoost,Mohsen Habibi,Zahra Noormohammadi et al.
Saeideh Alidoost et al.
Background: Prostate cancer (PCa) as the first men's common cancer in the world and the third cancer in Iranian men is a heterogeneous disorder which sometimes several biopsies are needed for its diagnosis. ...
The modified vaccination technique designed to prevent and cure acute and chronic disorders [0.03%]
一种用于预防和治疗急慢性疾病的改良型疫苗技术的设计
Arpad Z Barabas,Chad D Cole,Zoltan B Kovacs et al.
Arpad Z Barabas et al.
In spite of enormous efforts there have been no solutions to date for preventing/terminating certain acute and chronic disorders of humans by vaccination or drugs. Yet it is well understood that if the target antigen (ag) could be presented...
Ulrich Storz
Ulrich Storz
Epitope-based antibody claims have emerged to become one of the most important claim species in antibody patents. At the same time, they are heavily disputed. This article strives to give an overview about the as is situation both in Europe...
The relationship between health literacy and quality of life among hemodialysis patients: An integrative review [0.03%]
血液透析患者的健康素养与生活质量之间的关系：整合回顾
Yisak Hagos Alemayehu,Khatereh Seylania,Fatemeh Bahramnezhad
Yisak Hagos Alemayehu
Background: Various studies have highlighted the correlates to health literacy and quality of life among patients receiving hemodialysis therapy. However, evidence of how these two outcomes could influence each other is n...
Assessment of the genes and molecular mechanisms of B cells activation through systems biology approaches [0.03%]
系统生物学方法评估B细胞活化基因和分子机制
Razieh Fatehi
Razieh Fatehi
Two classes of T helper lymphocytes, Th1 and Th2, have different roles in B cell activation based on specific cytokines. To understand the difference of molecular mechanisms of B cell activation, the microarray dataset of B cells co-culture...
Sepideh Dashti,Zahra Taherian-Esfahani
Sepideh Dashti
Background: Cancer-germline genes are a class of genes that are normally expressed in testis, trophoblast and few somatic tissues but abnormally expressed in tumor tissues. Their expression signature indicates that they c...
Former antiplatelet drug administration and consequences of intravenous thrombolysis in acute ischemic stroke [0.03%]
急性缺血性卒中患者静脉溶栓治疗前的抗聚集药物应用及其结局分析
Mojtaba Khazaei,Arezou Davoodian,Mohammad Taheri et al.
Mojtaba Khazaei et al.
Background: One of the concerns in patients with acute ischemic stroke with former history of taking antiplatelet drugs is the risk of intracerebral hemorrhage following venous thrombolysis. The purpose of this study was ...
Nanobodies: The "Magic Bullets" in therapeutics, drug delivery and diagnostics [0.03%]
纳米抗体：治疗、药物输送和诊断中的“魔法子弹”
Manzoor A Mir,Umar Mehraj,Bashir Ahmad Sheikh et al.
Manzoor A Mir et al.
Antibodies represent a well-established class of clinical diagnostics for medical applications as well as essential research and biotechnological tools. Although both polyclonal and monoclonal antibodies are indispensable reagents in basic ...