E-selectin, but not CRP, partially mediates the association between metabolic indices and insulin resistance in older adults: a mediation analysis [0.03%]
老年人大血管炎症标志物介导代谢指标与胰岛素抵抗关系的作用研究：中介分析方法
Laith Ashour,Tariq Albweitel,Juana Abu Rahmeh et al.
Laith Ashour et al.
Background: Evidence on the pathophysiology of insulin resistance (IR), particularly the mediating role of inflammatory markers, remains limited. Objectiv...
The association of clinical characteristics and liver stiffness measurement with liver viscosity measured by shear wave elastography in patient with non-alcoholic fatty liver disease [0.03%]
剪切波弹性成像技术评估非酒精性脂肪肝患者肝脏黏弹性的临床意义研究
Anchasa Opasatian,Natthaporn Tanpowpong,Pisit Tangkijvanich
Anchasa Opasatian
Background: Viscosity plane-wave ultrasound (Vi.PLUS) measures tissue viscosity by using shear wave dispersion within tissues. The tissue viscosity is associated with the degree of liver necroinflammation, which is an imp...
Antimicrobial functional ingredients used in hand hygiene products: a cross-sectional survey on regional e-commerce platforms in Wuhan area of China [0.03%]
我国武汉市地区电商平台中手卫生产品中使用的抗菌功能成分的横断面调查研究
Xintong Chen,Jun Wang
Xintong Chen
Background: Hand hygiene products containing antimicrobial functional ingredients have become daily products for many people during the post-pandemic period. However, their current market scenarios have not been well expl...
Anticancer potential of fused heterocycles: structural insights and mechanistic advances [0.03%]
融合杂环的抗肿瘤潜力：结构见解和机制进展
Aaysha Pandey,Shubham Sharma,Kamal Kishore et al.
Aaysha Pandey et al.
β-lactam derivatives, carbazoles, isatin derivatives, pyrrolo-benzodiazepines (PBDs), and pyrido[2,3-d]pyrimidines have demonstrated potential as anticancer agents among organic compounds. They exhibit substantial anticancer efficacy acros...
A beginner's guide to the clinical approach and key concepts of glomerular disease: a mini review [0.03%]
关于肾小球疾病的临床方法和关键概念的入门指南：迷你综述
Suwasin Udomkarnjananun,Talerngsak Kanjanabuch,Dennis A Hesselink
Suwasin Udomkarnjananun
Glomerular disease is a common issue in nephrology, where prompt diagnosis and appropriate treatment are crucial to halting disease progression and preventing the development of chronic kidney disease or end-stage kidney disease. The initia...
Recombinant phospholipase A2 inhibitor of Sinonatrix annularis (ringed water snake) attenuates hemorrhagic action of the venom from Daboia siamensis (Siamese Russell's viper) [0.03%]
环蛇重组型磷脂酶A2抑制剂可缓解学蛇毒的出血作用
Wichit Thaveekarn,Jureeporn Noiphrom,Asada Leelahavanichkul et al.
Wichit Thaveekarn et al.
Background: Phospholipase A2 (PLA2) is a common enzyme in snake venoms from many species that hydrolyzes phospholipids in cell membranes, causing local and systemic adverse effects. Interestingly, PLA2 inhibitors in the s...
Sirisawat Kunanon,Praew Kotruchin,Pairoj Chattranukulchai et al.
Sirisawat Kunanon et al.
The committee of the 2024 Thai Guidelines on the Treatment of Hypertension has reviewed new developments in the body of knowledge, combined with expertise in real-life clinical practice and evidence collected from clinical studies worldwide...
Evaluating plasma and tissue biopsy for DNA methylation markers in early colorectal cancer detection: a systematic review [0.03%]
评估血浆和组织活检样本中的DNA甲基化标志物在早期结直肠癌检测中的应用：系统性回顾
Hans Ezekiel T Olorosisimo,Charlemagne G Sumperos,Aeryll Lesley A Adviento et al.
Hans Ezekiel T Olorosisimo et al.
Background: DNA methylation markers are emerging as promising diagnostic tools for the early detection of colorectal cancer (CRC) that can significantly improve survival rates. ...
Mobile health and hypertension in the digital era: patient perspectives on mHealth adoption and self-management in Saudi Arabia aligned with the digital health objectives of vision 2030 [0.03%]
数字化时代下的移动健康与高血压：沙特阿拉伯患者对mHealth采纳及自我管理的视角与数字健康的2030愿景目标一致
Sultan M Alshahrani
Sultan M Alshahrani
Background: Hypertension remains a prominent public health concern in Saudi Arabia, contributing to cardiovascular morbidity and mortality. With widespread smartphone use and the national push toward digital transformatio...