Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine [0.03%]
肾脏病理生理学与心血管医学交叉领域的三大药物基因组学和个性化医学应用
Murielle Bochud,Michel Burnier,Idris Guessous
Murielle Bochud
Pharmacogenomics is a field with origins in the study of monogenic variations in drug metabolism in the 1950s. Perhaps because of these historical underpinnings, there has been an intensive investigation of 'hepatic pharmacogenes' such as C...
Pharmacogenomics in Primary Care: A Crucial Entry Point for Global Personalized Medicine? [0.03%]
初级保健中的药物基因组学：全球精准医学的重要切入点吗？
Gillian Bartlett,Nathalie Zgheib,Aresha Manamperi et al.
Gillian Bartlett et al.
Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation [0.03%]
南非的药物基因组学研究：彩虹国的经验与未来机遇
Louise Warnich,Britt I Drögemöller,Michael S Pepper et al.
Louise Warnich et al.
South Africa, like many other developing countries, stands to benefit from novel diagnostics and drugs developed by pharmacogenomics guidance due to high prevalence of disease burden in the region. This includes both communicable (e.g., HIV...
End of the Beginning and Public Health Pharmacogenomics: Knowledge in 'Mode 2' and P5 Medicine [0.03%]
结束的开始和公共卫生药理基因组学：“模式2”知识与P5医学
Vural Ozdemir,Erik Fisher,Edward S Dove et al.
Vural Ozdemir et al.
Towards an Ecology of Collective Innovation: Human Variome Project (HVP), Rare Disease Consortium for Autosomal Loci (RaDiCAL) and Data-Enabled Life Sciences Alliance (DELSA) [0.03%]
迈向集体创新的生态学：人类变异体项目（HVP）、常染色体位点罕见疾病联盟（RaDiCAL）和数据驱动生命科学联盟（DELSA）
Vural Ozdemir,David S Rosenblatt,Louise Warnich et al.
Vural Ozdemir et al.
Ethical and Policy Considerations in the Application of Pharmacogenomic Testing for Tardive Dyskinesia: Case Study of the Dopamine D3 Receptor [0.03%]
药物基因组学在迟发性运动障碍中的应用伦理及政策考量：多巴胺D3受体的病例研究
Michel C F Shamy,Clement Zai,Vincenzo S Basile et al.
Michel C F Shamy et al.
Tardive dyskinesia (TD) is a serious adverse effect often associated with the first generation antipsychotic medications used in the management of mental health disorders such as schizophrenia. Pharmacogenomics is the study of human genomic...
Forward Look: Tenth Anniversary of the Human Genome Sequence and 21 Century Postgenomics Global Health - A Close Up on Africa and Women's Health [0.03%]
展望：人类基因组序列第十周年以及二十一世纪后基因组时代的全球卫生——聚焦非洲和妇女健康
Sanaa M Kamal,Louise Warnich,Lynnette R Ferguson et al.
Sanaa M Kamal et al.
Personalized Medicine in the Age of Pharmacoproteomics: A Close up on India and Need for Social Science Engagement for Responsible Innovation in Post-Proteomic Biology [0.03%]
后蛋白质组学时代个性化医药的社会科学参与——以印度为例及负责任创新之必要性
Panga Jaipal Reddy,Rekha Jain,Young-Ki Paik et al.
Panga Jaipal Reddy et al.
Anatasha Crawford,Rita Nahta
Anatasha Crawford
Acquired resistance to Herceptin is a major clinical problem in the treatment of HER2-overexpressing breast cancer. Understanding the molecular mechanisms leading to resistance will allow identification of novel therapeutic targets and pred...
Stem Cell Transplantation for Hematological Malignancies: Prospects for Personalized Medicine and Co-therapy with Mesenchymal Stem Cells [0.03%]
造血系统恶性肿瘤的干细胞移植：个性化医疗及间充质干细胞联合治疗的发展前景
Shyam A Patel,Pranela Rameshwar
Shyam A Patel
Bone marrow transplantation is a form of cell therapy that has been in practice for decades for the treatment of hematological disorders and solid tumors. Immunosuppressive therapy has been a mainstay for treatment, but the severity of the ...