Dynamic Biomarkers of Response to Antiangiogenic Therapies in Colorectal Cancer: A Review [0.03%]
抗血管生成疗法治疗结直肠癌应答的动态生物标志物：综述
Jesus Rodriguez-Pascual,Antonio Cubillo
Jesus Rodriguez-Pascual
Background: Identification of clinical and molecular biomarkers to predict dynamic response or monitor in real-time the efficacy of antiangiogenic therapy represents a major point in the treatment of patients with advance...
Ethical, Political and Societal Implications of the Open Access Journal Movement in the Era of Economic Crisis, with Emphasis on Public Health Pharmacogenomics [0.03%]
经济危机时代的开放存取期刊运动的伦理、政治和社会影响——重点关注公共健康药物基因组学
Nicola Luigi Bragazzi
Nicola Luigi Bragazzi
Publication of the research outputs is a vital step of the research processes and a gateway between the laboratory and the global society. Open Access is revolutionizing the dissemination of scientific ideas, particularly in the field of pu...
Taking the Kidney Personally: The Quest for Novel Antigens of Idiopathic Membranous Nephropathy through Proteomic Approaches - Per Ardua Ad Astra? [0.03%]
个性化的肾脏：通过蛋白质组学方法寻找特发性膜性肾病的新抗原——艰难困苦，玉汝于成？
Ana Konvalinka,Sanjeeva Srivastava,Mario Masellis
Ana Konvalinka
A Conceptual Model of Psychoneurological Symptom Cluster Variation in Women with Breast Cancer: Bringing Nursing Research to Personalized Medicine [0.03%]
乳腺癌女性患者心理神经症状群变异的概念模型：将护理研究带入精准医学
Angela R Starkweather,Debra E Lyon,R K Elswick Jr et al.
Angela R Starkweather et al.
Personalized medicine applies knowledge about the patient's individual characteristics in relation to health and intervention outcomes, including treatment response and adverse side-effects, to develop a tailored treatment plan. For women w...
Mechanisms of Adipocytokine-Mediated Trastuzumab Resistance in HER2-Positive Breast Cancer Cell Lines [0.03%]
HER2阳性乳腺癌细胞系中由脂肪细胞细胞因子介导的曲妥珠单抗耐药机制研究
Samantha E Griner,Katherine J Wang,Jayashree P Joshi et al.
Samantha E Griner et al.
Acquired resistance to trastuzumab is a clinical problem in the treatment of HER2-over-expressing metastatic breast cancer. Importantly, an earlier report suggested that high body mass index was associated with reduced overall survival and ...
Situating Nutri-Ethics at the Junction of Nutrigenomics and Nutriproteomics in Postgenomics Medicine [0.03%]
后基因组医学中营养伦理学在营养基因组学和蛋白质组学的交叉口的发展定位
Nicola Luigi Bragazzi
Nicola Luigi Bragazzi
Food has societal, economic, medical and ethical implications, being fundamental for life. It plays an important role also in sports medicine, since a healthy diet is an important part of an athlete's training. Nutrigenomics and nutriproteo...
Commercial Opportunities and Ethical Pitfalls in Personalized Medicine: A Myriad of Reasons to Revisit the Myriad Genetics Saga [0.03%]
个性化医疗的商业机遇与伦理困境——兼论Myriad Genetics公司案例再思考
Derek So,Yann Joly
Derek So
In 1996, the US-based biotechnology company Myriad Genetics began offering genetic diagnostic tests for mutations in the genes BRCA1 and BRCA2, which are linked to hereditary breast and ovarian cancer. Since that time, Myriad has been a for...
Public Health Pharmacogenomics and the Design Principles for Global Public Goods - Moving Genomics to Responsible Innovation [0.03%]
公共卫生药理基因组学及全球公共物品的设计原则——推动基因组向负责任的创新方向发展
Vural Ozdemir,Alexander Borda-Rodriguez,Edward S Dove et al.
Vural Ozdemir et al.
Role of Statistical Random-Effects Linear Models in Personalized Medicine [0.03%]
统计随机效应线性模型在精准医疗中的作用
Francisco J Diaz,Hung-Wen Yeh,Jose de Leon
Francisco J Diaz
Some empirical studies and recent developments in pharmacokinetic theory suggest that statistical random-effects linear models are valuable tools that allow describing simultaneously patient populations as a whole and patients as individual...
Epigenetic Regulation in Particulate Matter-Mediated Cardiopulmonary Toxicities: A Systems Biology Perspective [0.03%]
基于系统生物学的颗粒物介导的心肺毒性的表观遗传调控研究
Ting Wang,Joe Gn Garcia,Wei Zhang
Ting Wang
Particulate matter (PM) air pollution exerts significant adverse health effects in global populations, particularly in developing countries with extensive air pollution. Understanding of the mechanisms of PM-induced health effects including...