Robert P Hoffman
Robert P Hoffman
Feimin in Glucose Homeostasis: Mechanistic Insights, Population Heterogeneity, and Therapeutic Potential [0.03%]
果 flies在血糖稳态中的作用：机制见解、人群异质性和治疗潜力
Sijun Yang
Sijun Yang
The recent discovery of feimin, a feeding-induced myokine modulating glucose homeostasis via the MERTK pathway, offers a novel therapeutic avenue for metabolic disorders. While other studies delineate its acute metabolic effects in Han Chin...
Bhagavathi Sundaram Sivamaruthi,Chaiyavat Chaiyasut,Kaliyappan Illakiya et al.
Bhagavathi Sundaram Sivamaruthi et al.
Diabetes mellitus (DM) is a growing global health concern, placing increasing strain on healthcare systems. Curcumin, the primary bioactive compound in Curcuma longa (turmeric), has been reported to exhibit several therapeutic effects, incl...
Juan Feng,Sien Lai,Dongsheng Tang
Juan Feng
Diabetic wounds constitute a significant global health challenge, affecting millions of individuals worldwide and imposing a substantial burden on healthcare systems. This review explores the complex pathophysiology of diabetic wound healin...
A Review on Diabulimia: Exploring the Intersection of Disordered Eating, Eating Disorders, Insulin Dose Manipulation, and Type 1 Diabetes [0.03%]
糖尿病性进食障碍综述：非典型失衡进食、进食障碍、胰岛素剂量调节和1型糖尿病之间的交叉点探究
Velimir Altabas,Jelena Marinković Radošević,Nika Grubiješić
Velimir Altabas
Background: Although insulin is essential for managing type 1 diabetes and is life-saving for patients with this condition, some individuals may intentionally reduce or omit insulin due to a fear of weight gain or a desir...
Sevket Ercan Tunc,Bulent Tolga Delibasi,Tuncay Delibasi
Sevket Ercan Tunc
Type 2 diabetes mellitus (T2DM) remains one of the most prevalent chronic metabolic disorders globally, presenting an ongoing challenge in terms of prevention and management. The majority of existing therapeutic strategies focus primarily o...
Preclinical Evaluation of Fisetin in the Management of Diabetic Foot Ulcer in Wistar Rats [0.03%]
山奈酚治疗威斯特大鼠糖尿病足溃疡的药效学评估研究
Aniket Gupta,Rishabh Chalotra,Randhir Singh
Aniket Gupta
Aims: Preclinical Evaluation of Fisetin in the Management of Diabetic Foot Ulcer in Wistar Rats. Introduction: Diabetic foot ulcer (DFU...
In Silico Exploration of Ayurvedic Extract for Targeting Diabetes Mellitus and Non-alcoholic Fatty Liver Disease Via GPR120 and GPR40 [0.03%]
基于GPR120和GPR40靶点的糖尿病和非酒精性脂肪肝病的印度草药Ayurvedic提取物的药物设计与虚拟筛选研究
Priyanka Sharma,Kalicharan Sharma,Anoop Kumar et al.
Priyanka Sharma et al.
Introduction: Type 2 Diabetes Mellitus (T2DM) is the most prevalent form of hyperglycemia, often coexisting with Non-Alcoholic Fatty Liver Disease (NAFLD), as both share disrupted glucose and lipid metabolic pathways. The...
Unraveling the Mechanisms of Diabetic Wounds: Insights into Pathogenesis and Advanced Treatment Strategies [0.03%]
糖尿病伤口机制解析：发病机制及先进治疗策略的洞见
Nur Shaid Mondal,Aminul Islam,Manish Kumar Gautam et al.
Nur Shaid Mondal et al.
Diabetic wounds are a class of chronic wounds that exhibit significant healing abnormalities due to dysregulated cytokines, growth factors, and unique cellular expressions, currently affecting an estimated 9.1-26.1 million people per year g...
Emerging Therapeutic Potential of Fisetin for Nephrotoxicity, Kidney Injury, and Nephropathy: A Systematic Review [0.03%]
山柰酚治疗肾毒性和肾脏疾病的潜在疗效：系统性综述
Saeed Mohajeri,Alizamen Salehifard Jouneghani,Saeid Heidari-Soureshjani et al.
Saeed Mohajeri et al.
Introduction/objective: Kidney diseases cause high morbidity and mortality worldwide. This study investigated the mechanistic effects of Fisetin (FIS) on nephrotoxicity, kidney injury, and nephropathy induced by drugs, to...