Discovering New Challenges in the Pharmacological and Non-Pharmacological Management of Insulin Resistance [0.03%]
发现胰岛素抵抗的药理学和非药理学管理中的新挑战
Rina Amelia,Chandra Pranata,Tasia Dewi et al.
Rina Amelia et al.
Introduction: Insulin resistance has become a serious health problem over time. As people age, the incidence of insulin resistance increases. Genetic factors in families with a history of type 2 diabetes are also key risk...
The Beneficial Effects of Combination Therapy With SGLT-2 Inhibitors and GLP-1 Receptor Agonists in Type 2 Diabetes Mellitus [0.03%]
钠-葡萄糖协同转运蛋白2抑制剂与胰高血糖素样肽1受体激动剂联合治疗2型糖尿病的益处
Aimilianos Kalogeris,Ignatios Ikonomidis,Konstantinos G Kyriakoulis et al.
Aimilianos Kalogeris et al.
Type 2 diabetes mellitus is a chronic metabolic disorder associated with microvascular and macrovascular complications. Hyperglycemia and insulin resistance are core pathophysiological components of diabetes, linked to subclinical inflammat...
Chain Mediating Role of Illness Perception and Fear of Hypoglycemia in Impaired Hypoglycemic Awareness and Mild Cognitive Impairment in Patients with Type 2 Diabetes Mellitus [0.03%]
2型糖尿病患者低血糖感知受损和轻度认知障碍中恐惧低血糖的介导作用链式模型研究
Mengyao Han,Xiangning Li,Yuying He et al.
Mengyao Han et al.
Introduction: Impaired hypoglycemic awareness (IAH) in type 2 diabetes mellitus (T2DM) is linked to mild cognitive impairment (MCI), but the underlying mechanisms are unclear. This study aimed to explore the chain mediati...
Targeting the Gut Microbiota in the Treatment of Type 2 Diabetes: Dietary Interventions, Microbial Preparations, and Fecal Transplantation [0.03%]
肠道菌群在2型糖尿病治疗中的作用：饮食干预、微生物制剂和粪便移植
Lingling Ding,Zhiyuan Xi,Yuxi Zou et al.
Lingling Ding et al.
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disease worldwide, characterized by hyperglycemia and insulin resistance (IR). Its escalating global prevalence and the associated morbidity and mortality render it a major pub...
Insulin Resistance as an Underlying Cause of Type 2 Diabetes in Adults Born with Low Birth Weight: A Narrative Review [0.03%]
低出生体重成人2型糖尿病的潜在原因——叙述性综述胰岛素抵抗
Sana Ahmed,Eram S Rao,Renuka Pathak et al.
Sana Ahmed et al.
Insulin, secreted by pancreatic β-cells, regulates blood glucose levels. Insulin resistance (IR), characterized by diminished cellular responsiveness, increases insulin demand, imposing stress on β-cells. This leads to β-cell decompensat...
Hybrid Deep Learning Framework for Continuous Blood Glucose Monitoring and Gestational Diabetes Risk Prediction [0.03%]
连续血糖监测和妊娠糖尿病风险预测的混合深度学习框架
Kiran Kumar Chanumolu,Muni Nagamani G,Muni Hemalatha G
Kiran Kumar Chanumolu
Background: Gestational diabetes mellitus (GDM) affects almost 10%-12% of pregnancies worldwide, threatening maternal and fetal life. Continuous glucose monitoring (CGM) forms the backbone of managing GDM, and the current...
Advances in Wound Healing Strategies for Diabetic Foot Ulcers: From Conventional to Regenerative Therapies [0.03%]
糖尿病足溃疡伤口愈合策略的进展：从传统治疗到再生医学疗法
Abdullah Alwahbi
Abdullah Alwahbi
Diabetic Foot Ulcer (DFU) is a serious and chronic complication of uncontrolled diabetes, significantly increasing the risk of amputation and mortality in diabetic patients. Conventional wound healing techniques often fail to manage chronic...
Chemical Interactions Involved in Insulin Receptor Activation: Scoping Review [0.03%]
胰岛素受体激活相关的化学相互作用：系统综述
Sofia Fernandes Coriolano Araujo,Stuart Handerson Rodrigues Costa,Antonio Souza Araujo
Sofia Fernandes Coriolano Araujo
This work overviews some complex molecular interactions and phosphorylation events in the insulin receptor (IR) signaling pathway and explains its central role in metabolic control, which starts from the synthesis and secretion of insulin b...
The Impact of Sarcopenia on Glucose and Insulin Dynamics: A Mathematical Model [0.03%]
sarcopenia对葡萄糖和胰岛素动态的影响：一种数学模型
Abdesslam Boutayeb,Mohamed Lamlili E N,Wiam Boutayeb
Abdesslam Boutayeb
Introduction: Diabetes and sarcopenia are major age-related health issues in the world. Due to their bidirectional relationship, they significantly impact the quality of life of elderly men and women, especially those ove...
From Diabetes to Dermatology: The Role of Teneligliptin in Bullous Pemphigoid Development [0.03%]
从糖尿病到皮肤病：Teneligliptin在大疱性类天疱疮发病中的作用
Md Sadique Hussain,Gurusha Bahl,Yumna Khan et al.
Md Sadique Hussain et al.
Bullous pemphigoid (BP) is an autoimmune blistering disease that especially presents in elderly patients, but recently, its incidence has increased in patients treated with inhibitors of dipeptidyl peptidase-4 (DPP-4), among which teneligli...