Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes [0.03%]
瘦素和瘦素受体缺陷啮齿类动物模型与人类2型糖尿病的相关性研究
Bingxuan Wang,P Charukeshi Chandrasekera,John J Pippin
Bingxuan Wang
Among the most widely used animal models in obesity-induced type 2 diabetes mellitus (T2DM) research are the congenital leptin- and leptin receptor-deficient rodent models. These include the leptin-deficient ob/ob mice and the leptin recept...
Neurotrophic factors for retinal ganglion cell neuropathy - with a special reference to diabetic neuropathy in the retina [0.03%]
视网膜神经节细胞神经病变的神经营养因素-尤其是糖尿病性视网膜神经病变
Guzel Bikbova,Toshiyuki Oshitari,Takayuki Baba et al.
Guzel Bikbova et al.
Diabetes mellitus is a disease with a devastating impact on population. Recent data revealed that early retinal neuropathy in patients with diabetic retinopathy involved a reduced expression of brain-derived neurotrophic factor. Retinal gan...
Diabetic foot and exercise therapy: step by step the role of rigid posture and biomechanics treatment [0.03%]
糖尿病足与运动疗法：循序渐进探讨固定姿势和生物力学治疗的作用
Piergiorgio Francia,Massimo Gulisano,Roberto Anichini et al.
Piergiorgio Francia et al.
Lower extremity ulcers represent a serious and costly complication of diabetes mellitus. Many factors contribute to the development of diabetic foot. Peripheral neuropathy and peripheral vascular disease are the main causes of foot ulcerati...
Type 2 diabetes and memory: using neuroimaging to understand the mechanisms [0.03%]
2型糖尿病与记忆：利用神经影像学了解其机制
Nicola Jones,Leigh M Riby,Rachel L C Mitchell et al.
Nicola Jones et al.
The most robust and frequently reported cognitive deficits in type 2 diabetes (DM2) are those that relate to memory. Behavioural research has identified a number of potential contributory physiological factors, including abnormalities in gl...
Stephen Fava
Stephen Fava
The prevalence of diabetes is increasing world-wide. Tight glycaemic control has been shown to reduce diabetes complications in a number of landmark trials. Apart from increasing the risk of microvascular and macrovascular disease, poor gly...
Norman E Cameron
Norman E Cameron
Association of serum uric acid and metabolic syndrome in type 2 diabetes [0.03%]
尿酸与2型糖尿病患者代谢综合征的相关性分析
Shokoufeh Bonakdaran,Banafsheh Kharaqani
Shokoufeh Bonakdaran
Aim: The relationship between elevated serum uric acid level and metabolic syndrome (MS) has been debated. There is no data concerning this relation in Iranian population-based studies. The aim of this study was to determ...
Rita Angélica Gómez-Díaz,Nayely Garibay-Nieto,Niels Wacher-Rodarte et al.
Rita Angélica Gómez-Díaz et al.
Latin America is among the regions with the highest diabetes-related burden. Research and treatment programs have increased in number and complexity in recent years, but they are focused in type 2 diabetes, because this condition explains a...
Role of endogenous GLP-1 and its agonists in osteopenia and osteoporosis: but we little know until tried [0.03%]
内源性GLP-1及其类似物在骨量减少及骨质疏松症中作用的研究：知之甚少，试之而后知
Athanasia Papazafiropoulou,Nikolaos Papanas,Stavros Pappas et al.
Athanasia Papazafiropoulou et al.
The present brief review looks at the evidence on the role of GLP-1 and its agonists in osteopenia and osteoporosis in type 2 diabetes (T2DM). There is accumulating data to suggest a favourable effect of GLP-1 on bone metabolism. However, m...
Assessment of pancreatic β-cell function: review of methods and clinical applications [0.03%]
胰腺β细胞功能评估：方法与临床应用的回顾
Eugenio Cersosimo,Carolina Solis-Herrera,Michael E Trautmann et al.
Eugenio Cersosimo et al.
Type 2 diabetes mellitus (T2DM) is characterized by a progressive failure of pancreatic β-cell function (BCF) with insulin resistance. Once insulin over-secretion can no longer compensate for the degree of insulin resistance, hyperglycemia...