Unraveling the Ties: Type 2 Diabetes and Parkinson's Disease - A Nano-Based Targeted Drug Delivery Approach [0.03%]
解密联系:第2型糖尿病与帕金森病——一种基于纳米技术的靶向药物输送方法研究
Sourav De,Sabyasachi Banerjee,Pallabita Rakshit et al.
Sourav De et al.
The link between Type 2 Diabetes (T2DM) and Parkinson's Disease (PD) dates back to the early 1960s, and ongoing research is exploring this association. PD is linked to dysregulation of dopaminergic pathways, neuroinflammation, decreased PPA...
Leila Ghassemifard,Masumeh Hasanlu,Negin Parsamanesh et al.
Leila Ghassemifard et al.
The epidemic of diabetes continues to be an increasing problem, and there is a need for new therapeutic strategies. There are several promising drugs and molecules in synthetic medicinal chemistry that are developing for diabetes. In additi...
Bioinformatics to Identify Biomarkers of Diabetic Nephropathy based on Sphingolipid Metabolism and their Molecular Mechanisms [0.03%]
基于鞘脂代谢的糖尿病肾病生物标志物的生物信息学识别及分子机制研究
Yaxian Ning,Xiaochun Zhou,Gouqin Wang et al.
Yaxian Ning et al.
Ackground: Diabetes mellitus (DM) frequently results in Diabetic Nephropathy (DN), which has a significant negative impact on the quality of life of diabetic patients. Sphingolipid metabolism is associated with diabetes, ...
Dharmendra Pradhan,Prafulla Kumar Sahu,Sukumar Purohit et al.
Dharmendra Pradhan et al.
Background: Diabetes Mellitus (DM) is an alarming health concern, affecting approximately 537 million people worldwide. As a leading cause of morbidity and mortality, DM demands a comprehensive understanding of its divers...
Analytical and Bioanalytical Methods for the Determination of Dipeptidyl Peptidase-4 Inhibitors in Various Matrices: A Comprehensive Review [0.03%]
用于各种基质中二肽基肽酶-4抑制剂测定的分析与生物分析方法综述
Sakshi Hadawale,Sanjay Sharma
Sakshi Hadawale
Background: DPP-4 inhibitors, or gliptins, are new oral antidiabetic drugs for type 2 diabetes. They help to regulate insulin and glucagon. These drugs have the advantage of a lower risk of hypoglycemia compared to some o...
Probiotic Supplementation during Pregnancy: Evaluating the Current Clinical Evidence Against Gestational Diabetes Mellitus [0.03%]
孕期补充益生菌:评估目前的临床证据以预防妊娠糖尿病
Eleni Pavlidou,Olga Alexatou,Gerasimos Tsourouflis et al.
Eleni Pavlidou et al.
Background: Gestational diabetes mellitus (GDM) constitutes a common metabolic disorder that could lead to deleterious short- and long-term complications in both the mother and her infant. Probiotic supplementation seems ...
Technology for the Management of Type 1 Diabetes Mellitus in Saudi Arabia and MENA Region: A Systematic Review [0.03%]
沙特阿拉伯和中东及北非地区1型糖尿病管理技术的系统评价
Ayman Al Hayek,Mohamed A Al Dawish
Ayman Al Hayek
Background: Diabetes technology in the form of digital health or medical devices holds a promise for improving the quality of life and glycemic outcomes. A comprehensive insight into diabetes technology and its impact in ...
A Scoping Review of GIS Mapping of Type 1 Diabetes in Children: Identifying Current Gaps and Future Research Directions Using PRISMA-ScR [0.03%]
儿童1型糖尿病GIS制图的综合审查:使用PRISMA-ScR识别当前缺口和未来的研究方向
Demi Miriam,Navendu Chaudhary,Sushil Yewale et al.
Demi Miriam et al.
Background: Type 1 Diabetes poses a significant public health threat, especially in low-and-middle countries, where resources are limited. The use of geographical information systems in diabetes research has shown the pot...
Phloridzin's Diabetic Wound Healing Potential through DPP-4 Enzyme Inhibition: A Review Article [0.03%]
花青素通过DPP-4酶抑制作用促进糖尿病伤口愈合的潜力:综述文章
Khushi Sharma,Vadivelan Ramachandran,Ashutosh Sharma et al.
Khushi Sharma et al.
Diabetic wound healing is a dynamic medical process that takes place in an environment within the body that is complex and contains elevated sugar levels, oxygen deprivation, and cellular oxidative stress. Phloridzin (Phlorizin) is one of t...
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus [0.03%]
与内脏脂肪相关FGF21功能受损引起的胰岛素抵抗是糖尿病的核心缺陷
Unnati Jain,Priyanka Srivastava,Ashwani Sharma et al.
Unnati Jain et al.
The Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid ox...